日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

LYST deficiency impairs autophagic lysosome reformation in neurons and alters lysosome number and size

LYST 缺乏会损害神经元中的自噬溶酶体重组,并改变溶酶体的数量和大小

Jenny Serra-Vinardell, Maxwell B Sandler, Raffaella De Pace, Javier Manzella-Lapeira, Antony Cougnoux, Keyvan Keyvanfar, Wendy J Introne, Joseph A Brzostowski, Michael E Ward, William A Gahl, Prashant Sharma, May Christine V Malicdan

BTK inhibitors, irrespective of ITK inhibition, increase efficacy of a CD19/CD3-bispecific antibody in CLL

BTK 抑制剂(无论 ITK 抑制与否)可增强 CD19/CD3 双特异性抗体在 CLL 中的疗效

Maissa Mhibik, Erika M Gaglione, David Eik, Ellen K Kendall, Amy Blackburn, Keyvan Keyvanfar, Maria Joao Baptista, Inhye E Ahn, Clare Sun, Junpeng Qi, Christoph Rader, Adrian Wiestner

Select Antitumor Cytotoxic CD8+ T Clonotypes Expand in Patients with Chronic Lymphocytic Leukemia Treated with Ibrutinib

接受伊布替尼治疗的慢性淋巴细胞白血病患者中选择性抗肿瘤细胞毒性 CD8+ T 细胞克隆型扩增

Maria Joao Baptista, Sivasubramanian Baskar, Erika M Gaglione, Keyvan Keyvanfar, Inhye E Ahn, Adrian Wiestner, Clare Sun

Eltrombopag Improves Erythroid Differentiation in a Human Induced Pluripotent Stem Cell Model of Diamond Blackfan Anemia

艾曲波帕可改善人类诱导性多能干细胞 Diamond Blackfan 贫血模型中的红细胞分化

Husam Qanash, Yongqin Li, Richard H Smith, Kaari Linask, Sara Young-Baird, Waleed Hakami, Keyvan Keyvanfar, John S Choy, Jizhong Zou, Andre Larochelle

Definitive hematopoietic stem/progenitor cells from human embryonic stem cells through serum/feeder-free organoid-induced differentiation

通过无血清/无饲养细胞类器官诱导分化,从人类胚胎干细胞中产生确定性造血干细胞/祖细胞

Selami Demirci, Juan J Haro-Mora, Alexis Leonard, Claire Drysdale, Daniela Malide, Keyvan Keyvanfar, Khaled Essawi, Raul Vizcardo, Naritaka Tamaoki, Nicholas P Restifo, John F Tisdale, Naoya Uchida

Interleukin-18 plays a dispensable role in murine and likely also human bone marrow failure

白细胞介素-18 在小鼠和人类骨髓衰竭中起着可有可无的作用

Zhijie Wu, Valentina Giudice, Jichun Chen, Wanling Sun, Zenghua Lin, Keyvan Keyvanfar, Nidhi Talasani, Sachiko Kajigaya, Xingmin Feng, Neal S Young

Robust generation of erythroid and multilineage hematopoietic progenitors from human iPSCs using a scalable monolayer culture system

利用可扩展的单层培养系统,从人类诱导多能干细胞(iPSCs)中高效生成红系和多系造血祖细胞

Juan Pablo Ruiz ,Guibin Chen ,Juan Jesus Haro Mora ,Keyvan Keyvanfar ,Chengyu Liu ,Jizhong Zou ,Jeanette Beers ,Hanan Bloomer ,Husam Qanash ,Naoya Uchida ,John F Tisdale ,Manfred Boehm ,Andre Larochelle

CRISPR/Cas9-mediated ASXL1 mutations in U937 cells disrupt myeloid differentiation

U937细胞中CRISPR/Cas9介导的ASXL1突变会破坏髓系分化。

Zhi-Jie Wu ,Xin Zhao ,Lauren G Banaszak ,Fernanda Gutierrez-Rodrigues ,Keyvan Keyvanfar ,Shou-Guo Gao ,Diego Quinones Raffo ,Sachiko Kajigaya ,Neal S Young

Single-cell RNA-seq reveals a distinct transcriptome signature of aneuploid hematopoietic cells

单细胞 RNA 测序揭示非整倍体造血细胞的独特转录组特征

Xin Zhao, Shouguo Gao, Zhijie Wu, Sachiko Kajigaya, Xingmin Feng, Qingguo Liu, Danielle M Townsley, James Cooper, Jinguo Chen, Keyvan Keyvanfar, Maria Del Pilar Fernandez Ibanez, Xujing Wang, Neal S Young

T Cell Transcriptomes from Paroxysmal Nocturnal Hemoglobinuria Patients Reveal Novel Signaling Pathways

阵发性睡眠性血红蛋白尿症患者的 T 细胞转录组揭示了新的信号通路

Kohei Hosokawa, Sachiko Kajigaya, Keyvan Keyvanfar, Wangmin Qiao, Yanling Xie, Danielle M Townsley, Xingmin Feng, Neal S Young