日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Fatty acid transport protein 2 inhibition enhances glucose tolerance through α cell-mediated GLP-1 secretion

脂肪酸转运蛋白2抑制通过α细胞介导的GLP-1分泌增强葡萄糖耐量

Khan, Shenaz; Gaivin, Robert J; Liu, Zhiyu; Li, Vincent; Samuels, Ivy; Son, Jinsook; Osei-Owusu, Patrick; Garvin, Jeffrey L; Accili, Domenico; Schelling, Jeffrey R

Fatty acids and albumin are transported by distinct mechanisms in the proximal tubule

脂肪酸和白蛋白在近端小管中通过不同的机制进行运输。

Garcia, Nestor H; Gaivin, Robert J; Khan, Shenaz; Li, Vincent; Rbaibi, Youssef; Weisz, Ora A; Garvin, Jeffrey L; Schelling, Jeffrey R

Fatty Acid Transport Protein-2 (FATP2) Inhibition Enhances Glucose Tolerance through α-Cell-mediated GLP-1 Secretion

脂肪酸转运蛋白-2 (FATP2) 抑制通过α细胞介导的GLP-1分泌增强葡萄糖耐量

Khan, Shenaz; Gaivin, Robert J; Liu, Zhiyu; Li, Vincent; Samuels, Ivy; Son, Jinsook; Osei-Owusu, Patrick; Garvin, Jeffrey L; Accili, Domenico; Schelling, Jeffrey R

Definition of fatty acid transport protein-2 (FATP2) structure facilitates identification of small molecule inhibitors for the treatment of diabetic complications

脂肪酸转运蛋白-2 (FATP2) 结构的明确定义有助于鉴定用于治疗糖尿病并发症的小分子抑制剂。

Kumar, Mukesh; Gaivin, Robert J; Khan, Shenaz; Fedorov, Yuriy; Adams, Drew J; Zhao, Weiyang; Lee, Hsueh-Yun; Dai, Xinghong; Dealwis, Chris G; Schelling, Jeffrey R

Ventricular arrhythmias in mouse models of diabetic kidney disease

糖尿病肾病小鼠模型中的室性心律失常

Laurita, Kenneth R; Khan, Shenaz; McMahon, Tracy; Dennis, Adrienne T; Li, Vincent; Gaivin, Robert; Sapa, Hima; Fu, Ji-Dong; Schelling, Jeffrey R

Kidney Proximal Tubule Lipoapoptosis Is Regulated by Fatty Acid Transporter-2 (FATP2)

肾近端小管脂质凋亡受脂肪酸转运蛋白-2 (FATP2) 调控

Khan, Shenaz; Cabral, Pablo D; Schilling, William P; Schmidt, Zachary W; Uddin, Asif N; Gingras, Amelia; Madhavan, Sethu M; Garvin, Jeffrey L; Schelling, Jeffrey R

Mesangial cell integrin αvβ8 provides glomerular endothelial cell cytoprotection by sequestering TGF-β and regulating PECAM-1.

系膜细胞整合素αvβ8通过隔离TGF-β和调节PECAM-1来提供肾小球内皮细胞的细胞保护作用

Khan Shenaz, Lakhe-Reddy Sujata, McCarty Joseph H, Sorenson Christine M, Sheibani Nader, Reichardt Louis F, Kim Jane H, Wang Bingcheng, Sedor John R, Schelling Jeffrey R

Beta8 integrin binds Rho GDP dissociation inhibitor-1 and activates Rac1 to inhibit mesangial cell myofibroblast differentiation

β8整合素结合Rho GDP解离抑制因子-1,激活Rac1,从而抑制系膜细胞向肌成纤维细胞分化。

Lakhe-Reddy, Sujata; Khan, Shenaz; Konieczkowski, Martha; Jarad, George; Wu, Karen L; Reichardt, Louis F; Takai, Yoshimi; Bruggeman, Leslie A; Wang, Bingcheng; Sedor, John R; Schelling, Jeffrey R