Tebentafusp, a T cell engager, promotes macrophage reprogramming and in combination with IL-2 overcomes macrophage immunosuppression in cancer
Tebentafusp 是一种 T 细胞衔接剂，可促进巨噬细胞重编程，并与 IL-2 联合使用可克服癌症中的巨噬细胞免疫抑制。
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-57470-w
Güç, Esra; Treveil, Agatha; Leach, Emma; Broomfield, Anna; Camera, Antonio; Clubley, James; Nieto Garcia, Paula; Kazachenka, Anastasiya; Khanolkar, Rahul; Del Carpio, Luis; Heyn, Holger; Hassel, Jessica C; Sacco, Joseph J; Stanhope, Sarah; Collins, Laura; Piulats, Josep M; Ranade, Koustubh; Benlahrech, Adel
巨噬细胞
肿瘤
T细胞
肿瘤免疫
细胞生物学
巨噬细胞
IL-2
发育与干细胞
免疫/内分泌
