日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Barriers to the Pharmacologic Rescue of W1282X CFTR

W1282X CFTR 药物治疗的障碍

Manfredi, Candela; Rab, Andras; Joshi, Disha; Winters, Ashlyn G; Jackson, JaNise J; Molina, Sam; Koval, Michael; Khazanov, Netaly; Jacobson, Madison; Oliver, Kathryn; Senderowitz, Hanoch; Sorscher, Eric J; Hong, Jeong S

Multimodal Inhibition of Pectobacterium brasiliense Virulence by the Citrus Flavanone Naringenin

柑橘黄酮柚皮苷对巴西果胶杆菌毒力的多模式抑制作用

Pun, Manoj; Galsurker, Ortal; Khazanov, Netaly; Charkowski, Amy; Yelin, Shani; Kerem, Zohar; Weitman, Michal; Senderowitz, Hanoch; Yedidia, Iris

RETRACTED: Naamneh et al. Structure-Activity Relationship of Synthetic Linear KTS-Peptides Containing Meta-Aminobenzoic Acid as Antagonists of α1β1 Integrin with Anti-Angiogenic and Melanoma Anti-Tumor Activities. Pharmaceuticals 2024, 17, 549

撤稿:Naamneh 等人,《含间氨基苯甲酸的合成线性 KTS 肽作为 α1β1 整合素拮抗剂的构效关系及其抗血管生成和抗黑色素瘤活性》,Pharmaceuticals 2024, 17, 549

Naamneh, Majdi Saleem; Momic, Tatjana; Klazas, Michal; Grosche, Julius; Eble, Johannes A; Marcinkiewicz, Cezary; Khazanov, Netaly; Senderowitz, Hanoch; Hoffman, Amnon; Gilon, Chaim; Katzhendler, Jehoshua; Lazarovici, Philip

Inhibition of AcrAB-TolC enhances antimicrobial activity of phytochemicals in Pectobacterium brasiliense

抑制 AcrAB-TolC 可增强巴西果胶杆菌中植物化学物质的抗菌活性

Pun, Manoj; Khazanov, Netaly; Galsurker, Ortal; Kerem, Zohar; Senderowitz, Hanoch; Yedidia, Iris

Hsp104 facilitates the endoplasmic-reticulum-associated degradation of disease-associated and aggregation-prone substrates

Hsp104促进内质网相关降解与疾病相关的和易聚集的底物。

Doonan, Lynley M; Guerriero, Christopher J; Preston, G Michael; Buck, Teresa M; Khazanov, Netaly; Fisher, Edward A; Senderowitz, Hanoch; Brodsky, Jeffrey L

Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator.

配体与远端位点的结合,从热力学角度纠正了人类囊性纤维化跨膜传导调节因子中的 F508del 突变

Wang Chi, Aleksandrov Andrei A, Yang Zhengrong, Forouhar Farhad, Proctor Elizabeth A, Kota Pradeep, An Jianli, Kaplan Anna, Khazanov Netaly, Boël Grégory, Stockwell Brent R, Senderowitz Hanoch, Dokholyan Nikolay V, Riordan John R, Brouillette Christie G, Hunt John F

Structural stability of purified human CFTR is systematically improved by mutations in nucleotide binding domain 1.

通过核苷酸结合域 1 的突变,可以系统地提高纯化的人类 CFTR 的结构稳定性

Yang Zhengrong, Hildebrandt Ellen, Jiang Fan, Aleksandrov Andrei A, Khazanov Netaly, Zhou Qingxian, An Jianli, Mezzell Andrew T, Xavier Bala M, Ding Haitao, Riordan John R, Senderowitz Hanoch, Kappes John C, Brouillette Christie G, Urbatsch Ina L

A novel image-based high-throughput screening assay discovers therapeutic candidates for adult polyglucosan body disease

一种新型的基于图像的高通量筛选方法发现了成人多聚葡萄糖体疾病的治疗候选药物。

Solmesky, Leonardo J; Khazanov, Netaly; Senderowitz, Hanoch; Wang, Peixiang; Minassian, Berge A; Ferreira, Igor M; Yue, Wyatt W; Lossos, Alexander; Weil, Miguel; Kakhlon, Or

Potentiators exert distinct effects on human, murine, and Xenopus CFTR

增强剂对人、小鼠和非洲爪蟾的CFTR蛋白具有不同的作用。

Cui, Guiying; Khazanov, Netaly; Stauffer, Brandon B; Infield, Daniel T; Imhoff, Barry R; Senderowitz, Hanoch; McCarty, Nael A

Challenging a paradigm: theoretical calculations of the protonation state of the Cys25-His159 catalytic diad in free papain

挑战传统范式:游离木瓜蛋白酶中Cys25-His159催化二元体质子化状态的理论计算

Shokhen, Michael; Khazanov, Netaly; Albeck, Amnon