日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Phase II Trial of Vemurafenib and Sorafenib Combination in Advanced KRAS-Mutated Metastatic Pancreatic Cancer

维莫非尼联合索拉非尼治疗KRAS突变晚期转移性胰腺癌的II期临床试验

期刊:Journal of Immunotherapy and Precision Oncology
影响因子:3.2
doi:10.36401/JIPO-25-20
Khawaja, Muhammad Rizwan; Jameson, Gayle; Cridebring, Derek; Shannon, Patricia; Han, Haiyong; Moore, Jaeger; Von Hoff, Daniel; Posner, Richard G; Hlavacek, William S; Kolch, Walter; Kholodenko, Boris N; Rukhlenko, Oleksii S; Roe, Denise J; Wertheim, Betsy C; Borazanci, Erkut
胰腺癌
肿瘤
RAS
肿瘤免疫
发表日期：2026
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VEGF counteracts shear stress-determined arterial fate specification during capillary remodeling

VEGF在毛细血管重塑过程中拮抗剪切应力决定的动脉命运。

期刊:
影响因子:
doi:10.1101/2024.01.23.576920
Chen, Dongying; Rukhlenko, Oleksii S; Joshi, Divyesh; Rudnicki, Martina; Coon, Brian G; Chakraborty, Raja; Tuliakova, Anna; Ioannou, Elena; Martin, Kathleen A; Ruhrberg, Christiana; Kholodenko, Boris N; Schwartz, Martin A; Simons, Michael
EGF
VEGF
发表日期：2025
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A structure-based modelling approach identifies effective drug combinations for RAS-mutant acute myeloid leukemia.

基于结构的建模方法可确定 RAS 突变型急性髓系白血病的有效药物组合

期刊:
影响因子:
doi:10.1101/2025.04.29.651188
Jones Luke, Rukhlenko Oleksii, Dias Tânia, Imoto Hiroaki, Carmody Ciardha, Wynne Kieran, Kholodenko Boris N, Bond Jonathan
肿瘤
白血病
药物研究
发表日期：2025
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Cell State Transition Models Stratify Breast Cancer Cell Phenotypes and Reveal New Therapeutic Targets

细胞状态转变模型对乳腺癌细胞表型进行分层，并揭示新的治疗靶点

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers16132354
Rukhlenko, Oleksii S; Imoto, Hiroaki; Tambde, Ayush; McGillycuddy, Amy; Junk, Philipp; Tuliakova, Anna; Kolch, Walter; Kholodenko, Boris N
细胞生物学
肿瘤
肿瘤免疫
乳腺癌
发表日期：2024
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Reversing pathological cell states: the road less travelled can extend the therapeutic horizon

逆转病理细胞状态：另辟蹊径或可拓展治疗前景

期刊:Trends in Cell Biology
影响因子:18.1
doi:10.1016/j.tcb.2023.04.004
Kholodenko, Boris N; Kolch, Walter; Rukhlenko, Oleksii S
细胞生物学
发表日期：2023
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From pandemic to endemic pedagogy: Being CLEAR in our teaching

从疫情到地方性教学法：清晰教学

期刊:Bio-protocol
影响因子:1.1
doi:10.21769/BioProtoc.4089
Rukhlenko, Oleksii S; Kholodenko, Boris N; Felten, Peter
发表日期：2022
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Relationship Between Dimensionality and Convergence of Optimization Algorithms: A Comparison Between Data-Driven Normalization and Scaling Factor-Based Methods Using PEPSSBI

维度与优化算法收敛性的关系：基于PEPSSBI的数据驱动归一化方法与基于缩放因子方法的比较

期刊:Methods in Molecular Biology
影响因子:
doi:10.1007/978-1-0716-1767-0_5
Degasperi, Andrea; Nguyen, Lan K; Fey, Dirk; Kholodenko, Boris N
发表日期：2022
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Systems biology approaches to macromolecules: the role of dynamic protein assemblies in information processing

系统生物学方法在生物大分子研究中的应用：动态蛋白质组装体在信息处理中的作用

期刊:Current Opinion in Structural Biology
影响因子:7
doi:10.1016/j.sbi.2020.09.007
Rukhlenko, Oleksii; Kholodenko, Boris N; Kolch, Walter
发表日期：2021
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Can Systems Biology Advance Clinical Precision Oncology?

系统生物学能否推动临床精准肿瘤学的发展？

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers13246312
Rocca, Andrea; Kholodenko, Boris N
肿瘤
肿瘤免疫
发表日期：2021
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New insights into RAS biology reinvigorate interest in mathematical modeling of RAS signaling

对 RAS 生物学的新见解重新激发了人们对 RAS 信号传导数学建模的兴趣。

期刊:Seminars in Cancer Biology
影响因子:15.7
doi:10.1016/j.semcancer.2018.02.008
Erickson, Keesha E; Rukhlenko, Oleksii S; Posner, Richard G; Hlavacek, William S; Kholodenko, Boris N
信号转导
RAS
发表日期：2019
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