日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective, and anti-inflammatory properties following status epilepticus in mice.

一种能穿过血脑屏障的肽-神经降压素缀合物,在小鼠癫痫持续状态后可诱导药理性低温,并具有抗惊厥、神经保护和抗炎特性

Ferhat Lotfi, Soussi Rabia, Masse Maxime, Kyriatzis Grigorios, Girard Stéphane, Gassiot Fanny, Gaudin Nicolas, Laurencin Mathieu, Bernard Anne, Bôle Angélique, Ferracci Géraldine, Smirnova Maria, Roman François, Dive Vincent, Cisternino Salvatore, Temsamani Jamal, David Marion, Lécorché Pascaline, Jacquot Guillaume, Khrestchatisky Michel

Neurotensin and Neurotensin Receptors in Stress-related Disorders: Pathophysiology & Novel Drug Targets

神经降压素及其受体在应激相关疾病中的作用:病理生理学及新型药物靶点

Kyriatzis, Grigorios; Khrestchatisky, Michel; Ferhat, Lotfi; Chatzaki, Ekaterini Alexiou

LDLR-Mediated Targeting and Productive Uptake of siRNA-Peptide Ligand Conjugates In Vitro and In Vivo

LDLR 介导的 siRNA-肽配体结合物的体内和体外靶向和有效摄取

Baptiste Broc, Karine Varini, Rose Sonnette, Belinda Pecqueux, Florian Benoist, Maxime Masse, Yasmine Mechioukhi, Géraldine Ferracci, Jamal Temsamani, Michel Khrestchatisky, Guillaume Jacquot, Pascaline Lécorché

Suppression of MT5-MMP Reveals Early Modulation of Alzheimer's Pathogenic Events in Primary Neuronal Cultures of 5xFAD Mice.

MT5-MMP 的抑制揭示了 5xFAD 小鼠原代神经元培养物中阿尔茨海默病致病事件的早期调控

Pilat Dominika, Paumier Jean-Michel, Louis Laurence, Manrique Christine, García-González Laura, Stephan Delphine, Bernard Anne, Pardossi-Piquard Raphaëlle, Checler Frédéric, Khrestchatisky Michel, Di Pasquale Eric, Baranger Kévin, Rivera Santiago

In the Rat Hippocampus, Pilocarpine-Induced Status Epilepticus Is Associated with Reactive Glia and Concomitant Increased Expression of CD31, PDGFRβ, and Collagen IV in Endothelial Cells and Pericytes of the Blood-Brain Barrier

在大鼠海马中,毛果芸香碱诱发的癫痫持续状态与反应性胶质细胞有关,同时血脑屏障内皮细胞和周细胞中 CD31、PDGFRβ 和胶原蛋白 IV 的表达增加

Grigorios Kyriatzis, Anne Bernard, Angélique Bôle, Michel Khrestchatisky, Lotfi Ferhat

MT5-MMP promotes neuroinflammation, neuronal excitability and Aβ production in primary neuron/astrocyte cultures from the 5xFAD mouse model of Alzheimer's disease

MT5-MMP 促进阿尔茨海默病 5xFAD 小鼠模型中的原代神经元/星形胶质细胞培养物中的神经炎症、神经元兴奋性和 Aβ 产生

Dominika Pilat #, Jean-Michel Paumier #, Laura García-González, Laurence Louis, Delphine Stephan, Christine Manrique, Michel Khrestchatisky, Eric Di Pasquale, Kévin Baranger, Santiago Rivera

LDL receptor-peptide conjugate as in vivo tool for specific targeting of pancreatic ductal adenocarcinoma

LDL 受体肽结合物作为胰腺导管腺癌的体内特异性靶向工具

Angélina Acier, Magali Godard #, Fanny Gassiot #, Pascal Finetti, Marion Rubis, Jonathan Nowak, François Bertucci, Juan L Iovanna, Richard Tomasini, Pascaline Lécorché, Guillaume Jacquot, Michel Khrestchatisky, Jamal Temsamani, Cédric Malicet, Sophie Vasseur, Fabienne Guillaumond

High levels of serum soluble TWEAK are associated with neuroinflammation during multiple sclerosis

血清可溶性TWEAK水平升高与多发性硬化症期间的神经炎症有关

Maarouf, Adil; Stephan, Delphine; Ranjeva, Marie-Pierre; Ranjeva, Jean-Philippe; Pelletier, Jean; Audoin, Bertrand; Khrestchatisky, Michel; Desplat-Jégo, Sophie

Long-Term Pantethine Treatment Counteracts Pathologic Gene Dysregulation and Decreases Alzheimer's Disease Pathogenesis in a Transgenic Mouse Model

长期泛硫乙胺治疗可对抗病理性基因失调,并降低转基因小鼠模型中阿尔茨海默病的发病率

Baranger, Kevin; van Gijsel-Bonnello, Manuel; Stephan, Delphine; Carpentier, Wassila; Rivera, Santiago; Khrestchatisky, Michel; Gharib, Bouchra; De Reggi, Max; Benech, Philippe

Metalloproteinases and their tissue inhibitors in Alzheimer's disease and other neurodegenerative disorders

金属蛋白酶及其组织抑制剂在阿尔茨海默病和其他神经退行性疾病中的作用

Rivera, Santiago; García-González, Laura; Khrestchatisky, Michel; Baranger, Kévin