日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural pathway for PI3-kinase regulation by VPS15 in autophagy

VPS15在自噬中调控PI3激酶的结构通路

Cook, Annan S I; Chen, Minghao; Nguyen, Thanh N; Cabezudo, Ainara Claveras; Khuu, Grace; Rao, Shanlin; Garcia, Samantha N; Yang, Mingxuan; Iavarone, Anthony T; Ren, Xuefeng; Lazarou, Michael; Hummer, Gerhard; Hurley, James H

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex.

人类自噬起始 ULK1C:PI3KC3-C1 超复合物的结构和激活。

Chen Minghao, Nguyen Thanh N, Ren Xuefeng, Khuu Grace, Cook Annan S I, Zhao Yuanchang, Yildiz Ahmet, Lazarou Michael, Hurley James H

The TECPR1:ATG5-ATG12 complex conjugates LC3/ATG8 to damaged lysosomes that expose luminal glycans in response to osmotic imbalance.

TECPR1:ATG5-ATG12 复合物将 LC3/ATG8 连接到受损的溶酶体上,从而在渗透压失衡时暴露腔内聚糖

Wang Yingxue, Jefferson Matthew, Ramos Maria, Whelband Matthew, Kreuzer Kristin, Khuu Grace, Lazarou Michael, Mccoll James, Lazenby James, Whitchurch Cynthia B, Verkade Paul, Mayer Ulrike, Wileman Thomas