日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Quantitative systems toxicology approach that integrates PBPK and core hepatic metabolism: a case study with valproic acid

整合生理药代动力学和核心肝脏代谢的定量系统毒理学方法：以丙戊酸为例

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2026.1768190
Gupta, Vipul; Jo, Heeseung; Fisher, Ciarán P; Kierzek, Andrzej M
代谢
发表日期：2026
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RNA Folding Nearest Neighbor Parameters Including the Modification 1-Methyl-Pseudouridine

RNA折叠最近邻参数，包括1-甲基假尿苷修饰

期刊:
影响因子:
doi:10.64898/2026.04.09.717343
Kierzek, Elzbieta; Shabangu, Thandolwethu S; Hiltke, Olivia M; Miaro, Megan; Arteaga, Sebastian; Znosko, Brent M; Jolley, Elizabeth A; Bevilacqua, Philip C; SantaLucia, John; SantaLucia, Holly A; Lin, Haining; Metkar, Mihir; Aviran, Sharon; Soszynska-Jozwiak, Marta; Kierzek, Ryszard; Mathews, David H
发表日期：2026
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Experimental and computational investigations of RNA duplexes containing N7-regioisomers of adenosine and LNA-adenosine

对含有腺苷N7-区域异构体和LNA-腺苷的RNA双链进行实验和计算研究

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkae1222
Yildirim, Ilyas; Andralojc, Witold; Taghavi, Amirhossein; Baranowski, Daniel; Gdaniec, Zofia; Kierzek, Ryszard; Kierzek, Elzbieta
发表日期：2025
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Delivery strategies for RNA-targeting therapeutic nucleic acids and RNA-based vaccines against respiratory RNA viruses: IAV, SARS-CoV-2, RSV

针对呼吸道RNA病毒（如IAV、SARS-CoV-2和RSV）的RNA靶向治疗性核酸和RNA疫苗的递送策略

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.1
doi:10.1016/j.omtn.2025.102572
Maziec, Kinga; Baliga-Gil, Agnieszka; Kierzek, Elzbieta
微生物学
SARS-CoV-2
发表日期：2025
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Towards new approach methodologies for biological therapeutics: a novel model-informed metric to assess immunogenicity risk

迈向生物治疗新方法：一种基于模型的新型免疫原性风险评估指标

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1677925
Rose, Rachel H; Shuaib, Aban; Wigbers, Manon; Khalifa, Maryam; Kierzek, Andrzej M; van der Graaf, Piet H
免疫/内分泌
发表日期：2025
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Accurate in silico predictions of modified RNA interactions to a prototypical RNA-binding protein with λ-dynamics

利用计算机模拟准确预测修饰RNA与具有λ动力学的典型RNA结合蛋白的相互作用

期刊:RNA
影响因子:5
doi:10.1261/rna.080367.124
Angelo, Murphy; Bhargava, Yash; Kierzek, Elzbieta; Kierzek, Ryszard; Hayes, Ryan L; Zhang, Wen; Vilseck, Jonah Z; Aoki, Scott Takeo
发表日期：2025
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Structural architecture of the human long non-coding RNA-PAAN as a potential target for anti-influenza drug development

人类长链非编码RNA-PAAN的结构架构作为抗流感药物研发的潜在靶点

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2025.110755
Ulanowska, Izabela; Kierzek, Ryszard; Kierzek, Elzbieta; Soszynska-Jozwiak, Marta
微生物学
流感
发表日期：2025
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The interaction of RNA G-quadruplexes from the influenza A virus vRNA with TMPyP4 and BRACO-19 ligands

甲型流感病毒vRNA的RNA G-四链体与TMPyP4和BRACO-19配体的相互作用

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0335975
Nalewaj, Maria; Sliwiak, Joanna; Zielinska, Karolina; Zmora, Pawel; Niedziałek, Dorota; Wieczorek, Grzegorz; Kierzek, Elzbieta; Szabat, Marta
微生物学
流感
发表日期：2025
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Membrane potential and feedback dynamics regulate CatSper-mediated progesterone signaling in human sperm

膜电位和反馈动力学调节人类精子中CatSper介导的孕酮信号传导

期刊:
影响因子:
doi:10.1101/2025.09.14.675619
Kierzek, Michelina; Fridman, Dmitry; Biagioni, Cristina; Miller, Evan W; Kaupp, U Benjamin; Brenker, Christoph; Strünker, Timo
信号转导
发表日期：2025
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Human fertilization in vivo and in vitro requires the CatSper channel to initiate sperm hyperactivation

人类体内和体外受精需要 CatSper 通道来启动精子过度活跃

期刊:Journal of Clinical Investigation
影响因子:13.3
doi:10.1172/JCI173564
Samuel Young, Christian Schiffer, Alice Wagner, Jannika Patz, Anton Potapenko, Leonie Herrmann, Verena Nordhoff, Tim Pock, Claudia Krallmann, Birgit Stallmeyer, Albrecht Röpke, Michelina Kierzek, Cristina Biagioni, Tao Wang, Lars Haalck, Dirk Deuster, Jan N Hansen, Dagmar Wachten, Benjamin Risse, He
Human
发表日期：2024
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