日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Metabolites from South African Medicinal Plants as Dual-Function Inhibitors of the SARS-CoV-2 Papain-like Protease (PL(pro))

南非药用植物代谢物作为SARS-CoV-2木瓜蛋白酶样蛋白酶（PL(pro)）的双功能抑制剂

期刊:Life-Basel
影响因子:3.4
doi:10.3390/life16030373
Makhafola, Mmamudi Anna; Naidoo, Clarissa Marcelle; Obi, Chikwelu Lawrence; Iweriebor, Benson Chuks; Olaokun, Oyinlola Oluwunmi; Prinsloo, Earl; Kikuchi, Haruhisa; Zubair, Muhammad Sulaiman; Mkolo, Nqobile Monate
SARS-CoV-2
代谢
发表日期：2026
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Ester derivatives of Dictyostelium differentiation-inducing factors exhibit antibacterial activity, possibly via a prodrug-like function

盘基网柄菌分化诱导因子的酯类衍生物具有抗菌活性，这可能是通过类似前药的功能实现的。

期刊:BMC Research Notes
影响因子:1.7
doi:10.1186/s13104-025-07122-5
Takahashi, Katsunori; Kikuchi, Haruhisa; Nishimura, Takehiro; Ishigaki, Hirotaka; Miura, Yusuke; Takahashi, Ayuko; Kubohara, Yuzuru
发表日期：2025
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Dictyostelium Differentiation-Inducing Factor 1 Promotes Glucose Uptake via Direct Inhibition of Mitochondrial Malate Dehydrogenase in Mouse 3T3-L1 Cells

盘基网柄菌分化诱导因子1通过直接抑制小鼠3T3-L1细胞线粒体苹果酸脱氢酶促进葡萄糖摄取

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms25031889
Kubohara, Yuzuru; Fukunaga, Yuko; Shigenaga, Ayako; Kikuchi, Haruhisa
线粒体
细胞生物学
Mouse
发表日期：2024
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Pharmacological Evidence That Dictyostelium Differentiation-Inducing Factor 1 Promotes Glucose Uptake Partly via an Increase in Intracellular cAMP Content in Mouse 3T3-L1 Cells

药理学证据表明，盘基网柄菌分化诱导因子 1 通过增加小鼠 3T3-L1 细胞内 cAMP 含量来促进葡萄糖摄取

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules28237926
Kubohara, Yuzuru; Fukunaga, Yuko; Kikuchi, Haruhisa; Kuwayama, Hidekazu
Mouse
发表日期：2023
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Derivatives of Differentiation-Inducing Factor 1 Differentially Control Chemotaxis and Stalk Cell Differentiation in Dictyostelium discoideum

分化诱导因子1的衍生物对盘基网柄菌的趋化性和柄细胞分化具有差异性调控作用

期刊:Biology-Basel
影响因子:3.5
doi:10.3390/biology12060873
Kuwayama, Hidekazu; Kikuchi, Haruhisa; Kubohara, Yuzuru
信号转导
细胞生物学
发表日期：2023
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Development of Indole Alkaloid-Type Dual Immune Checkpoint Inhibitors Against CTLA-4 and PD-L1 Based on Diversity-Enhanced Extracts

基于多样性增强提取物的抗CTLA-4和PD-L1吲哚生物碱型双重免疫检查点抑制剂的开发

期刊:Frontiers in Chemistry
影响因子:4.2
doi:10.3389/fchem.2021.766107
Suzuki, Yoshihide; Ichinohe, Keisuke; Sugawara, Akihiro; Kida, Shinya; Murase, Shinya; Zhang, Jing; Yamada, Osamu; Hattori, Toshio; Oshima, Yoshiteru; Kikuchi, Haruhisa
Checkpoint
发表日期：2021
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Mg, K-containing microparticle: A possible active principle of a culture extract produced by a microbial consortium

含镁、钾微粒：微生物群落产生的培养提取物的一种可能活性成分

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0259297
Higashinakagawa, Toru; Kikuchi, Haruhisa; Kuwayama, Hidekazu
微生物学
发表日期：2021
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Conformational heterogeneity in apo and drug-bound structures of Toxoplasma gondii prolyl-tRNA synthetase

弓形虫脯氨酰tRNA合成酶的apo结构和药物结合结构的构象异质性

期刊:Acta Crystallographica Section F-Structural Biology Communications
影响因子:1.1
doi:10.1107/S2053230X19014808
Mishra, Siddhartha; Malhotra, Nipun; Kumari, Shreya; Sato, Mizuki; Kikuchi, Haruhisa; Yogavel, Manickam; Sharma, Amit
发表日期：2019
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Dictyostelium: An Important Source of Structural and Functional Diversity in Drug Discovery

盘基网柄菌：药物发现中结构和功能多样性的重要来源

期刊:Cells
影响因子:5.2
doi:10.3390/cells8010006
Kubohara, Yuzuru; Kikuchi, Haruhisa
发表日期：2018
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Evidence that differentiation-inducing factor-1 controls chemotaxis and cell differentiation, at least in part, via mitochondria in D. discoideum

证据表明，分化诱导因子-1至少部分通过线粒体控制盘基网柄菌的趋化性和细胞分化。

期刊:Biology Open
影响因子:1.7
doi:10.1242/bio.021345
Kubohara, Yuzuru; Kikuchi, Haruhisa; Nguyen, Van Hai; Kuwayama, Hidekazu; Oshima, Yoshiteru
细胞生物学
线粒体
发表日期：2017
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