日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

NR1D1 downregulation in astrocytes induces a phenotype that is detrimental to cocultured motor neurons

星形胶质细胞中的 NR1D1 下调会诱导对共培养运动神经元有害的表型

Kelby M Killoy, Benjamin A Harlan, Mariana Pehar, Marcelo R Vargas

Altered expression of clock and clock-controlled genes in a hSOD1-linked amyotrophic lateral sclerosis mouse model

hSOD1 关联的肌萎缩侧索硬化症小鼠模型中时钟和时钟控制基因的表达改变

Kelby M Killoy, Mariana Pehar, Benjamin A Harlan, Marcelo R Vargas

FABP7 upregulation induces a neurotoxic phenotype in astrocytes

FABP7 上调会诱发星形胶质细胞的神经毒性表型

Kelby M Killoy, Benjamin A Harlan, Mariana Pehar, Marcelo R Vargas

Evaluation of the NAD+ biosynthetic pathway in ALS patients and effect of modulating NAD+ levels in hSOD1-linked ALS mouse models

评估 ALS 患者的 NAD+ 生物合成途径以及调节 hSOD1 相关 ALS 小鼠模型中的 NAD+ 水平的影响

Benjamin A Harlan, Kelby M Killoy, Mariana Pehar, Liping Liu, Johan Auwerx, Marcelo R Vargas

Effects of RAGE inhibition on the progression of the disease in hSOD1G93A ALS mice

RAGE 抑制对 hSOD1G93A ALS 小鼠病情进展的影响

Liping Liu, Kelby M Killoy, Marcelo R Vargas, Yasuhiko Yamamoto, Mariana Pehar

Enhanced SIRT6 activity abrogates the neurotoxic phenotype of astrocytes expressing ALS-linked mutant SOD1

增强的 SIRT6 活性可消除表达 ALS 关联突变 SOD1 的星形胶质细胞的神经毒性表型

Benjamin A Harlan, Mariana Pehar, Kelby M Killoy, Marcelo R Vargas

Nitration and Glycation Turn Mature NGF into a Toxic Factor for Motor Neurons: A Role for p75NTR and RAGE Signaling in ALS

硝化和糖化将成熟的 NGF 转变为运动神经元的毒性因子:p75NTR 和 RAGE 信号在 ALS 中的作用

Mi Jin Kim, Marcelo R Vargas, Benjamin A Harlan, Kelby M Killoy, Lauren E Ball, Susana Comte-Walters, Monika Gooz, Yasuhiko Yamamoto, Joseph S Beckman, Luis Barbeito, Mariana Pehar

Decreased glutathione levels cause overt motor neuron degeneration in hSOD1WT over-expressing mice

谷胱甘肽水平降低导致 hSOD1WT 过表达小鼠出现明显的运动神经元退化

Kelby M Killoy, Benjamin A Harlan, Mariana Pehar, Kristi L Helke, Jeffrey A Johnson, Marcelo R Vargas

Role and Therapeutic Potential of Astrocytes in Amyotrophic Lateral Sclerosis

星形胶质细胞在肌萎缩侧索硬化症中的作用和治疗潜力

Pehar, Mariana; Harlan, Benjamin A; Killoy, Kelby M; Vargas, Marcelo R