日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Single-cell analysis identifies Ifi27l2a as a gene regulator of microglial inflammation in the context of aging and stroke in mice.

单细胞分析发现 Ifi27l2a 是小鼠衰老和中风背景下小胶质细胞炎症的基因调节因子

Kim Gab Seok, Harmon Elisabeth, Gutierrez Manuel C, Kim Sodam, Vance Lauren, Burrous Haven, Stephenson Jessica M, Chauhan Anjali, Banerjee Anik, Wise Zachary, Doan Andrea, Ahn John, Wu Ting, Bautista-Garrido Jesus, Lee Juneyoung, Tan Chunfeng, Jung Joo Eun, McCullough Louise D, Wythe Joshua D, Marrelli Sean P

Astrocytic mitochondria modulate poststroke splenic immune responses, promote interleukin 10 production, and mediate neuroprotection after intracerebral hemorrhage.

星形胶质细胞线粒体调节中风后脾脏免疫反应,促进白细胞介素 10 的产生,并在脑出血后介导神经保护作用

Tashiro Ryosuke, Kitamura Yuki, Bautista-Garrido Jesus, Sun Guanghua, Kim Gab Seok, Aronowski Jaroslaw, Jung Joo Eun

Ifi27l2a acts as a cytokine that promotes a pro-inflammatory phenotype in microglia and enhances neuroinflammation.

Ifi27l2a 作为一种细胞因子,可促进小胶质细胞的促炎表型,并增强神经炎症。

Kim Sodam, Burrous Haven, Harmon Elisabeth, Vance Lauren, Wu Ting, Andersohn Alexander, Doan Andrea, Wolocko Darby, Wise Zachary, Kitamura Yuki, Jung Joo Eun, Colpo Gabriela, Couture Lucy, Blixt Frank, McCullough Louise, Marrelli Sean, Kim Gab Seok

Single-cell analysis identifies Ifi27l2a as a novel gene regulator of microglial inflammation in the context of aging and stroke.

单细胞分析发现 Ifi27l2a 是衰老和中风背景下小胶质细胞炎症的新型基因调节因子

Kim Gab Seok, Harmon Elisabeth, Gutierrez Manuel, Stephenson Jessica, Chauhan Anjali, Banerjee Anik, Wise Zachary, Doan Andrea, Wu Ting, Lee Juneyoung, Jung Joo Eun, McCullough Louise, Wythe Joshua, Marrelli Sean

Increased Expression of Interferon-Induced Transmembrane 3 (IFITM3) in Stroke and Other Inflammatory Conditions in the Brain

脑卒中及其他炎症性疾病中脑内干扰素诱导跨膜蛋白3 (IFITM3) 表达增加

Harmon, Elisabeth; Doan, Andrea; Bautista-Garrido, Jesus; Jung, Joo Eun; Marrelli, Sean P; Kim, Gab Seok

Critical role of sphingosine-1-phosphate receptor 2 (S1PR2) in acute vascular inflammation

鞘氨醇-1-磷酸受体2 (S1PR2) 在急性血管炎症中的关键作用

Zhang, Guoqi; Yang, Li; Kim, Gab Seok; Ryan, Kieran; Lu, Shulin; O'Donnell, Rebekah K; Spokes, Katherine; Shapiro, Nathan; Aird, William C; Kluk, Michael J; Yano, Kiichiro; Sanchez, Teresa

Induction of thioredoxin-interacting protein is mediated by oxidative stress, calcium, and glucose after brain injury in mice

小鼠脑损伤后,氧化应激、钙和葡萄糖介导硫氧还蛋白相互作用蛋白的诱导表达。

Kim, Gab Seok; Jung, Joo Eun; Narasimhan, Purnima; Sakata, Hiroyuki; Chan, Pak H

Oxidative stress in ischemic brain damage: mechanisms of cell death and potential molecular targets for neuroprotection

缺血性脑损伤中的氧化应激:细胞死亡机制和神经保护的潜在分子靶点

Chen, Hai; Yoshioka, Hideyuki; Kim, Gab Seok; Jung, Joo Eun; Okami, Nobuya; Sakata, Hiroyuki; Maier, Carolina M; Narasimhan, Purnima; Goeders, Christina E; Chan, Pak H

NADPH oxidase is involved in post-ischemic brain inflammation

NADPH氧化酶参与缺血后脑炎症反应。

Chen, Hai; Kim, Gab Seok; Okami, Nobuya; Narasimhan, Purnima; Chan, Pak H

Mitochondrial and apoptotic neuronal death signaling pathways in cerebral ischemia

脑缺血中的线粒体和凋亡神经元死亡信号通路

Niizuma, Kuniyasu; Yoshioka, Hideyuki; Chen, Hai; Kim, Gab Seok; Jung, Joo Eun; Katsu, Masataka; Okami, Nobuya; Chan, Pak H