日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Synergistic enhancement of PARP inhibition via small molecule UNI66-mediated suppression of BRD4-dependent transcription of RAD51 and CtIP.

通过小分子 UNI66 介导抑制 BRD4 依赖的 RAD51 和 CtIP 转录,协同增强 PARP 抑制作用

Amarsanaa Enkhzul, Wie Minwoo, Shin Unbeom, Bilal Nabeela, Hwang Jungme, Lee Eun A, Lee Seon Young, Kim Byung-Gyu, Kim Shinseog, Lee Yoonsung, Myung Kyungjae

ATAD5 functions as a regulatory platform for Ub-PCNA deubiquitination

ATAD5 作为 Ub-PCNA 去泛素化的调控平台发挥作用

Ryu, Eunjin; Yoo, Juyeong; Kang, Mi-Sun; Ha, Na Young; Jang, Yewon; Kim, Jinwoo; Kim, Yeongjae; Kim, Byung-Gyu; Kim, Shinseog; Myung, Kyungjae; Kang, Sukhyun

Ewing sarcoma protein promotes dissociation of poly(ADP-ribose) polymerase 1 from chromatin

尤文氏肉瘤蛋白促进聚(ADP-核糖)聚合酶1与染色质分离

Seon-Gyeong Lee, Namwoo Kim, Su-Min Kim, In Bae Park, Hyejin Kim, Shinseog Kim, Byung-Gyu Kim, Jung Me Hwang, In-Joon Baek, Anton Gartner, Jun Hong Park, Kyungjae Myung

PRMT5 protects genomic integrity during global DNA demethylation in primordial germ cells and preimplantation embryos

PRMT5 在原始生殖细胞和植入前胚胎的整体 DNA 去甲基化过程中保护基因组完整性

Kim, Shinseog; Günesdogan, Ufuk; Zylicz, Jan J; Hackett, Jamie A; Cougot, Delphine; Bao, Siqin; Lee, Caroline; Dietmann, Sabine; Allen, George E; Sengupta, Roopsha; Surani, M Azim

Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation.

Prdm14 通过抑制 FGF 信号传导和 DNA 甲基化来促进生殖细胞命运和原始多能性

Grabole Nils, Tischler Julia, Hackett Jamie A, Kim Shinseog, Tang Fuchou, Leitch Harry G, Magnúsdóttir Erna, Surani M Azim

The germ cell determinant Blimp1 is not required for derivation of pluripotent stem cells

生殖细胞决定因子Blimp1并非多能干细胞分化所必需。

Bao, Siqin; Leitch, Harry G; Gillich, Astrid; Nichols, Jennifer; Tang, Fuchou; Kim, Shinseog; Lee, Caroline; Zwaka, Thomas; Li, Xihe; Surani, M Azim