Delivery of AAV-IGF-1 to the CNS extends survival in ALS mice through modification of aberrant glial cell activity
将AAV-IGF-1递送至中枢神经系统可通过调节异常的神经胶质细胞活性延长ALS小鼠的生存期。
期刊:Molecular Therapy
影响因子:12
doi:10.1038/mt.2008.60
Dodge, James C; Haidet, Amanda M; Yang, Wendy; Passini, Marco A; Hester, Mark; Clarke, Jennifer; Roskelley, Eric M; Treleaven, Christopher M; Rizo, Liza; Martin, Heather; Kim, Soo H; Kaspar, Rita; Taksir, Tatyana V; Griffiths, Denise A; Cheng, Seng H; Shihabuddin, Lamya S; Kaspar, Brian K
