Modulation of SETDB1 activity by APQ ameliorates heterochromatin condensation, motor function, and neuropathology in a Huntington's disease mouse model
APQ 调节 SETDB1 活性可改善亨廷顿氏病小鼠模型中的异染色质凝聚、运动功能和神经病理学
期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.6
doi:10.1080/14756366.2021.1900160
Yu Jin Hwang, Seung Jae Hyeon, Younghee Kim, Sungsu Lim, Min Young Lee, Jieun Kim, Ashwini M Londhe, Lizaveta Gotina, Yunha Kim, Ae Nim Pae, Yong Seo Cho, Jihye Seong, Hyemyung Seo, Yun Kyung Kim, Hyunah Choo, Hoon Ryu, Sun-Joon Min