Multiomics identifies a cholesterol-TFEB-PLD3-TLR9 axis driving immunosuppressive tumor-associated macrophage polarization in esophageal squamous cell carcinoma
多组学分析发现，胆固醇-TFEB-PLD3-TLR9轴驱动食管鳞状细胞癌中免疫抑制性肿瘤相关巨噬细胞的极化。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2520427123
Tan, Licheng; Zhou, Hongyu; Zhang, Baifeng; Kwong, Dora Lai Wan; Jia, Yongxu; Huang, Jiayi; Siu, Kin To Hugo; Zhang, Shuang; Huang, Jiao; Luo, Jie; Yang, Yuma; Liu, Qin; Lyu, Yingchen; Ban, Liuxian; Qi, Ziyang; Yu, Nanzhou; He, Chaohui; Zhang, Weiguang; Qin, Yanru; Liu, Beilei; Guan, Xinyuan
代谢
免疫/内分泌
细胞生物学
TLR9
巨噬细胞
巨噬细胞
TFEB
肿瘤
肿瘤免疫
