日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

High-throughput single-cell density measurements enable dynamic profiling of immune cell and drug response from patient samples

高通量单细胞密度测量能够对患者样本中的免疫细胞和药物反应进行动态分析

Wu, Weida; Ishamuddin, Sarah H; Quinn, Thomas W; Yerrum, Smitha; Zhang, Ye; Debaize, Lydie L; Kao, Pei-Lun; Duquette, Sarah Marie; Murakami, Mark A; Mohseni, Morvarid; Chow, Kin-Hoe; Miettinen, Teemu P; Ligon, Keith L; Manalis, Scott R

Measuring single-cell density with high throughput enables dynamic profiling of immune cell and drug response from patient samples

高通量测量单细胞密度可以动态分析患者样本的免疫细胞和药物反应

Weida Wu, Sarah H Ishamuddin, Thomas W Quinn, Smitha Yerrum, Ye Zhang, Lydie L Debaize, Pei-Lun Kao, Sarah Marie Duquette, Mark A Murakami, Morvarid Mohseni, Kin-Hoe Chow, Teemu P Miettinen, Keith L Ligon, Scott R Manalis

Dynamic BH3 profiling identifies pro-apoptotic drug combinations for the treatment of malignant pleural mesothelioma

动态BH3谱分析可识别用于治疗恶性胸膜间皮瘤的促凋亡药物组合

Danielle S Potter ,Ruochen Du ,Stephan R Bohl ,Kin-Hoe Chow ,Keith L Ligon ,Raphael Bueno ,Anthony Letai

Cancer-associated fibroblasts are the main contributors to epithelial-to-mesenchymal signatures in the tumor microenvironment

癌症相关成纤维细胞是肿瘤微环境中上皮-间质特征的主要贡献者

Peter M Szabo, Amir Vajdi, Namit Kumar, Michael Y Tolstorukov, Benjamin J Chen, Robin Edwards, Keith L Ligon, Scott D Chasalow, Kin-Hoe Chow, Aniket Shetty, Mohan Bolisetty, James L Holloway, Ryan Golhar, Brian A Kidd, Philip Ansumana Hull, Jeff Houser, Logan Vlach, Nathan O Siemers, Saurabh Saha

VRK1 as a synthetic lethal target in VRK2 promoter-methylated cancers of the nervous system

VRK1 作为 VRK2 启动子甲基化神经系统癌症的合成致死靶点

Jonathan So, Nathaniel W Mabe, Bernhard Englinger, Kin-Hoe Chow, Sydney M Moyer, Smitha Yerrum, Maria C Trissal, Joana G Marques, Jason J Kwon, Brian Shim, Sangita Pal, Eshini Panditharatna, Thomas Quinn, Daniel A Schaefer, Daeun Jeong, David L Mayhew, Justin Hwang, Rameen Beroukhim, Keith L Ligon, 

LGG-48. The influence of different FGFR1 alterations on pediatric low-grade glioma tumor biology and targeted therapy response

LGG-48。不同FGFR1改变对儿童低级别胶质瘤肿瘤生物学和靶向治疗反应的影响

Naz-McLean, Sarah; Kim, Andy; Zimmer, Andrew; Laibinis, Hannah; Lapan, Jen; Tyman, Paul; Hung, Jessica; Kelly, Christina; Nagireddy, Himaja; Narayanan-Pandit, Surya; McCarthy, Margaret; Ratnaparkhi, Saee; Rutherford, Henry; Patel, Rajesh; Dryden-Peterson, Scott; Hung, Deborah T; Woolley, Ann E; Cosimi, Lisa A; Morin, Eric; DiGiacomo, Jeromy; Novikov, Dana; Malinowski, Seth; Chow, Kin-Hoe; Jones, David; Alexandrescu, Sanda; Ligon, Keith; Bandopadhayay, Pratiti

Enhanced Efficacy of Aurora Kinase Inhibitors in G2/M Checkpoint Deficient TP53 Mutant Uterine Carcinomas Is Linked to the Summation of LKB1-AKT-p53 Interactions

Aurora 激酶抑制剂在 G2/M 检查点缺陷型 TP53 突变型子宫癌中的疗效增强与 LKB1-AKT-p53 相互作用的总和有关

Katherine N Lynch, Joyce F Liu, Nikolas Kesten, Kin-Hoe Chow, Aniket Shetty, Ruiyang He, Mosammat Faria Afreen, Liping Yuan, Ursula A Matulonis, Whitfield B Growdon, Michael G Muto, Neil S Horowitz, Colleen M Feltmate, Michael J Worley Jr, Ross S Berkowitz, Christopher P Crum, Bo R Rueda, Sarah J Hi

Correction: Selective colonization ability of human fecal microbes in different mouse gut environments

更正:人类粪便微生物在不同小鼠肠道环境中的选择性定植能力

Zhou, Wei; Chow, Kin-Hoe; Fleming, Elizabeth; Oh, Julia

TMOD-34. PATIENT-DERIVED XENOGRAFT AND CELL LINE MODELS FACILITATE NOVEL TREATMENT DISCOVERY IN CENTRAL NERVOUS SYSTEM LYMPHOMAS

TMOD-34. 患者来源的异种移植和细胞系模型有助于发现中枢神经系统淋巴瘤的新疗法

Bushel, Pierre R; Meredith, David; Chow, Kin Hoe; Kao, Pei-Lun; Zeng, Yu; Sinha, Rileen; Shetty, Aniket; Tolstorukov, Michael; Tran, Tony; Yerrum, Smitha; Chukwueke, Ugonma; Bi, Wenya Linda; Arnaout, Omar; Smith, Timothy; Ligon, Keith; Nayak, Lakshmi

miR-147b-mediated TCA cycle dysfunction and pseudohypoxia initiate drug tolerance to EGFR inhibitors in lung adenocarcinoma

miR-147b 介导的 TCA 循环功能障碍和假性缺氧引发肺腺癌对 EGFR 抑制剂的耐药性

Wen Cai Zhang, Julie M Wells, Kin-Hoe Chow, He Huang, Min Yuan, Tanvi Saxena, Mary Ann Melnick, Katerina Politi, John M Asara, Daniel B Costa, Carol J Bult, Frank J Slack