日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Measuring single-cell density with high throughput enables dynamic profiling of immune cell and drug response from patient samples

高通量测量单细胞密度可以动态分析患者样本的免疫细胞和药物反应

Weida Wu, Sarah H Ishamuddin, Thomas W Quinn, Smitha Yerrum, Ye Zhang, Lydie L Debaize, Pei-Lun Kao, Sarah Marie Duquette, Mark A Murakami, Morvarid Mohseni, Kin-Hoe Chow, Teemu P Miettinen, Keith L Ligon, Scott R Manalis

Dynamic BH3 profiling identifies pro-apoptotic drug combinations for the treatment of malignant pleural mesothelioma

动态BH3谱分析可识别用于治疗恶性胸膜间皮瘤的促凋亡药物组合

Danielle S Potter ,Ruochen Du ,Stephan R Bohl ,Kin-Hoe Chow ,Keith L Ligon ,Raphael Bueno ,Anthony Letai

Cancer-associated fibroblasts are the main contributors to epithelial-to-mesenchymal signatures in the tumor microenvironment

癌症相关成纤维细胞是肿瘤微环境中上皮-间质特征的主要贡献者

Peter M Szabo, Amir Vajdi, Namit Kumar, Michael Y Tolstorukov, Benjamin J Chen, Robin Edwards, Keith L Ligon, Scott D Chasalow, Kin-Hoe Chow, Aniket Shetty, Mohan Bolisetty, James L Holloway, Ryan Golhar, Brian A Kidd, Philip Ansumana Hull, Jeff Houser, Logan Vlach, Nathan O Siemers, Saurabh Saha

VRK1 as a synthetic lethal target in VRK2 promoter-methylated cancers of the nervous system

VRK1 作为 VRK2 启动子甲基化神经系统癌症的合成致死靶点

Jonathan So, Nathaniel W Mabe, Bernhard Englinger, Kin-Hoe Chow, Sydney M Moyer, Smitha Yerrum, Maria C Trissal, Joana G Marques, Jason J Kwon, Brian Shim, Sangita Pal, Eshini Panditharatna, Thomas Quinn, Daniel A Schaefer, Daeun Jeong, David L Mayhew, Justin Hwang, Rameen Beroukhim, Keith L Ligon, 

Enhanced Efficacy of Aurora Kinase Inhibitors in G2/M Checkpoint Deficient TP53 Mutant Uterine Carcinomas Is Linked to the Summation of LKB1-AKT-p53 Interactions

Aurora 激酶抑制剂在 G2/M 检查点缺陷型 TP53 突变型子宫癌中的疗效增强与 LKB1-AKT-p53 相互作用的总和有关

Katherine N Lynch, Joyce F Liu, Nikolas Kesten, Kin-Hoe Chow, Aniket Shetty, Ruiyang He, Mosammat Faria Afreen, Liping Yuan, Ursula A Matulonis, Whitfield B Growdon, Michael G Muto, Neil S Horowitz, Colleen M Feltmate, Michael J Worley Jr, Ross S Berkowitz, Christopher P Crum, Bo R Rueda, Sarah J Hi

miR-147b-mediated TCA cycle dysfunction and pseudohypoxia initiate drug tolerance to EGFR inhibitors in lung adenocarcinoma

miR-147b 介导的 TCA 循环功能障碍和假性缺氧引发肺腺癌对 EGFR 抑制剂的耐药性

Wen Cai Zhang, Julie M Wells, Kin-Hoe Chow, He Huang, Min Yuan, Tanvi Saxena, Mary Ann Melnick, Katerina Politi, John M Asara, Daniel B Costa, Carol J Bult, Frank J Slack

Enhancing the efficacy of glycolytic blockade in cancer cells via RAD51 inhibition

通过抑制 RAD51 增强癌细胞中糖酵解阻断的功效

John J Wilson, Kin-Hoe Chow, Nathan J Labrie, Jane A Branca, Thomas J Sproule, Bryant R A Perkins, Elise E Wolf, Mauro Costa, Grace Stafford, Christine Rosales, Kevin D Mills, Derry C Roopenian, Muneer G Hasham

Expression and function of ABCG2 and XIAP in glioblastomas

ABCG2和XIAP在胶质母细胞瘤中的表达和功能

Ivette F Emery ,Archana Gopalan ,Stephanie Wood ,Kin-Hoe Chow ,Chiara Battelli ,Joshy George ,Hagen Blaszyk ,Jeffrey Florman ,Kyuson Yun

The SUMO proteases SENP1 and SENP2 play a critical role in nucleoporin homeostasis and nuclear pore complex function

SUMO 蛋白酶 SENP1 和 SENP2 在核孔蛋白稳态和核孔复合体功能中起关键作用

Kin-Hoe Chow, Suzanne Elgort, Mary Dasso, Maureen A Powers, Katharine S Ullman

Two distinct sites in Nup153 mediate interaction with the SUMO proteases SENP1 and SENP2

Nup153 中有两个不同的位点介导与 SUMO 蛋白酶 SENP1 和 SENP2 的相互作用

Kin-Hoe Chow, Suzanne Elgort, Mary Dasso, Katharine S Ullman