日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Safety and Tolerability of Berzosertib, an Ataxia-Telangiectasia-Related Inhibitor, and Veliparib, an Oral Poly (ADP-ribose) Polymerase Inhibitor, in Combination With Cisplatin in Patients With Refractory Solid Tumors

Berzosertib（一种共济失调毛细血管扩张症相关抑制剂）和 Veliparib（一种口服聚（ADP-核糖）聚合酶抑制剂）联合顺铂治疗难治性实体瘤患者的安全性和耐受性

期刊:Jco Precision Oncology
影响因子:5.6
doi:10.1200/PO-25-00055
O'Sullivan Coyne, Geraldine; Do, Khanh T; Kummar, Shivaani; Piha-Paul, Sarina; Rubinstein, Lawrence; Kinders, Robert; Parchment, Ralph E; Wilsker, Deborah; Ferry-Galow, Katherine; Miller, Brandon; Takebe, Naoko; Juwara, Lamin; Ong, Mary Jane; Bruns, Ashley; Hogu, Murielle; Naqash, Abdul Rafeh; Mittra, Arjun; Voth, Andrea Regier; Doroshow, James H; Chen, Alice P
发表日期：2025
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A phase 1 study of orally administered 5-fluoro-2'-deoxycytidine with tetrahydrouridine in patients with refractory solid tumors

一项针对难治性实体瘤患者的口服5-氟-2'-脱氧胞苷联合四氢尿苷的I期研究

期刊:Cancer Chemotherapy and Pharmacology
影响因子:2.3
doi:10.1007/s00280-025-04844-y
Chen, Alice P; Kummar, Shivaani; Rubinstein, Larry; Zlott, Jennifer; Coyne, Geraldine O'Sullivan; Chung, Vincent; Newman, Edward M; Lenz, Heinz-Josef; Kelly, Karen; Villaruz, Liza C; Konaté, Mariam M; Ferry-Galow, Katherine V; Wang, Lihua; Kinders, Robert J; Parchment, Ralph E; Covey, Joseph M; Holleran, Julianne L; Piekarz, Richard L; Miller, Sarah B; Juwara, Lamin; Beumer, Jan H; Doroshow, James H
发表日期：2025
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Adjuvant COX inhibition augments STING signaling and cytolytic T cell infiltration in irradiated 4T1 tumors

辅助性COX抑制剂可增强STING信号传导和细胞毒性T细胞在受照射的4T1肿瘤中的浸润

期刊:JCI Insight
影响因子:6.3
doi:10.1172/jci.insight.165356
Lisa A Ridnour ，Robert Ys Cheng ，Noemi Kedei ，Veena Somasundaram ，Dibyangana D Bhattacharyya ，Debashree Basudhar ，Adelaide L Wink ，Abigail J Walke ，Caleb Kim ，William F Heinz ，Elijah F Edmondson ，Donna O Butcher ，Andrew C Warner ，Tiffany H Dorsey ，Milind Pore ，Robert J Kinders ，Stanley Lipkowitz ，Richard J Bryant ，Jens Rittscher ，Stephen Tc Wong ，Stephen M Hewitt ，Jenny C Chang ，Aliaa Shalaby ，Grace M Callagy ，Sharon A Glynn ，Stefan Ambs ，Stephen K Anderson ，Daniel W McVicar ，Stephen J Lockett ，David A Wink
细胞生物学
毒理研究
信号转导
肿瘤
STING
T细胞
免疫/内分泌
肿瘤免疫
T细胞
发表日期：2024
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Tumor NOS2 and COX2 Spatial Juxtaposition with CD8+ T Cells Promote Metastatic and Cancer Stem Cell Niches that Lead to Poor Outcome in ER- Breast Cancer

肿瘤 NOS2 和 COX2 与 CD8+ T 细胞的空间并置促进转移性和癌症干细胞微环境，导致 ER- 乳腺癌预后不良

期刊:Cancer Research Communications
影响因子:2
doi:10.1158/2767-9764.CRC-24-0235
Lisa A Ridnour #, William F Heinz #, Robert Y S Cheng #, Adelaide L Wink #, Noemi Kedei, Milind Pore, Fatima Imtiaz, Elise L Femino, Ana L Gonzalez, Leandro L Coutinho, Rebecca L Moffat, Donna Butcher, Elijah F Edmondson, Xiaoxian Li, Maria Cristina Rangel, Robert J Kinders, Jens Rittscher, Stanley
肿瘤
乳腺癌
干细胞
Mouse
iNOS
发表日期：2024
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Interferon-gamma is quintessential for NOS2 and COX2 expression in ER- breast tumors that lead to poor outcome

干扰素-γ 是内质网型乳腺肿瘤中 NOS2 和 COX2 表达的典型特征，会导致不良预后

期刊:Cell Death & Disease
影响因子:8.1
doi:10.1038/s41419-023-05834-9
Robert Y S Cheng #, Lisa A Ridnour #, Adelaide L Wink, Ana L Gonzalez, Elise L Femino, Helene Rittscher, Veena Somasundaram, William F Heinz, Leandro Coutinho, M Cristina Rangel, Elijah F Edmondson, Donna Butcher, Robert J Kinders, Xiaoxian Li, Stephen T C Wong, Daniel W McVicar, Stephen K Anderson,
肿瘤
乳腺癌
发表日期：2023
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NOS2 and COX2 Provide Key Spatial Targets that Determine Outcome in ER- Breast Cancer

NOS2 和 COX2 提供决定 ER-乳腺癌结果的关键空间靶点

期刊:
影响因子:
doi:10.1101/2023.12.21.572859
Lisa A Ridnour, William F Heinz, Robert Ys Cheng, Adelaide L Wink, Noemi Kedei, Milind Pore, Fatima Imtiaz, Elise L Femino, Ana L Gonzalez, Leandro Coutinho, Donna Butcher, Elijah F Edmondson, M Cristina Rangel, Robert J Kinders, Stanley Lipkowitz, Stephen Tc Wong, Stephen K Anderson, Danial W McVic
肿瘤
乳腺癌
发表日期：2023
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Systemic Nos2 Depletion and Cox inhibition limits TNBC disease progression and alters lymphoid cell spatial orientation and density

系统性NOS2耗竭和COX抑制可限制三阴性乳腺癌的疾病进展，并改变淋巴细胞的空间排列和密度。

期刊:Redox Biology
影响因子:10.7
doi:10.1016/j.redox.2022.102529
Veena Somasundaram ，Lisa A Ridnour ，Robert Ys Cheng ，Abigail J Walke ，Noemi Kedei ，Dibyangana D Bhattacharyya ，Adelaide L Wink ，Elijah F Edmondson ，Donna Butcher ，Andrew C Warner ，Tiffany H Dorsey ，David A Scheiblin ，William Heinz ，Richard J Bryant ，Robert J Kinders ，Stanley Lipkowitz ，Stephen Tc Wong ，Milind Pore ，Stephen M Hewitt ，Daniel W McVicar ，Stephen K Anderson ，Jenny Chang ，Sharon A Glynn ，Stefan Ambs ，Stephen J Lockett ，David A Wink
细胞生物学
乳腺癌
肿瘤
肿瘤免疫
发表日期：2022
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A Selective Copper Based Oxygen Reduction Catalyst for the Electrochemical Synthesis of H(2)O(2) at Neutral pH

一种用于中性pH条件下电化学合成H₂O₂的选择性铜基氧还原催化剂

期刊:ChemElectroChem
影响因子:3.5
doi:10.1002/celc.202101692
van Dijk, Bas; Kinders, Rick; Ferber, Thimo H; Hofmann, Jan P; Hetterscheid, Dennis G H
发表日期：2022
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Profiling DNA damage in 3D Histology Samples

三维组织学样本中DNA损伤的分析

期刊:
影响因子:
doi:10.1007/978-3-031-16961-8_9
Peñas, Kristofer E Delas; Haeusler, Ralf; Feng, Sally; Magidson, Valentin; Dmitrieva, Mariia; Wink, David; Lockett, Stephen; Kinders, Robert; Rittscher, Jens
毒理研究
发表日期：2022
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TET2 and DNMT3A mutations and exceptional response to 4'-thio-2'-deoxycytidine in human solid tumor models

TET2 和 DNMT3A 突变以及人类实体瘤模型中对 4'-硫代-2'-脱氧胞苷的特殊反应

期刊:Journal of Hematology & Oncology
影响因子:29.5
doi:10.1186/s13045-021-01091-5
Sherry X Yang, Melinda Hollingshead, Larry Rubinstein, Dat Nguyen, Angelo B A Larenjeira, Robert J Kinders, Michael Difilippantonio, James H Doroshow
肿瘤
Human
发表日期：2021
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