日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Author Correction: Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity

作者更正:缺氧诱导中性粒细胞祖细胞组蛋白剪切和H3K4me3丢失,导致中性粒细胞免疫功能长期受损。

Sanchez-Garcia, Manuel A; Sadiku, Pranvera; Ortmann, Brian M; Wit, Niek; Negishi, Yutaka; Coelho, Patricia; Zhang, Ailiang; Pednekar, Chinmayi; Howden, Andrew J M; Griffith, David M; Seear, Rachel; Kindrick, Jessica D; Mengede, Janine; Cooper, George; Morrison, Tyler; Watts, Emily R; Shimeld, Benjamin T; Reyes, Leila; Mirchandani, Ananda S; Arienti, Simone; Xu, Xiang; Thomson, Alexander; Brenes, Alejandro J; Turton, Helena A; Dowey, Rebecca; Hull, Rebecca C; Davidson-Smith, Hazel; McLaren, Amy; Deans, Andrew; Choudhury, Gourab; Doverman, Katherine; Hope, David; Vick, Oliver; Woodhead, Alastair; Petrie, Isla; Green, Suzanne; Rzechorzek, Nina M; Turtle, Lance; Openshaw, Peter J M; Semple, Malcolm G; Sproul, Duncan; Baillie, J Kenneth; Thompson, Alfred A R; Mole, David R; von Kriegsheim, Alex; Whyte, Moira K B; Mhlanga, Musa M; Nathan, James A; Walmsley, Sarah R

Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity

缺氧诱导中性粒细胞祖细胞中组蛋白剪切和H3K4me3丢失,导致中性粒细胞免疫功能长期受损。

Manuel A Sanchez-Garcia ,Pranvera Sadiku # ,Brian M Ortmann # ,Niek Wit # ,Yutaka Negishi # ,Patricia Coelho ,Ailiang Zhang ,Chinmayi Pednekar ,Andrew J M Howden ,David M Griffith ,Rachel Seear ,Jessica D Kindrick ,Janine Mengede ,George Cooper ,Tyler Morrison ,Emily R Watts ,Benjamin T Shimeld ,Leila Reyes ,Ananda S Mirchandani ,Simone Arienti ,Xiang Xu ,Alexander Thomson ,Alejandro J Brenes ,Helena A Turton ,Rebecca Dowey ,Rebecca C Hull ,Hazel Davidson-Smith ,Amy McLaren ,Andrew Deans ,Gourab Choudhury ,Katherine Doverman ,David Hope ,Oliver Vick ,Alastair Woodhead ,Isla Petrie ,Suzanne Green ,Nina M Rzechorzek ,Lance Turtle ,Peter J M Openshaw ,Malcolm G Semple ,J Kenneth Baillie ,Alfred A R Thompson ,David R Mole ,Alex von Kriegsheim ,Moira K B Whyte ,Musa M Mhlanga ,James A Nathan ,Sarah R Walmsley

Direct Co-Targeting of Bcl-xL and Mcl-1 Exhibits Synergistic Effects in AR-V7-Expressing CRPC Models.

Bcl-xL 和 Mcl-1 的直接共同靶向在 AR-V7 表达的 CRPC 模型中表现出协同效应

Brim Benjamin C, Leon Andres F, Beatson Erica L, Kindrick Jessica D, Bhadresha Kinjal, Zhang Xiaohu, Napoli Giulia C, Risdon Emily N, Schmidt Keith T, Wilson Kelli M, McKnight Crystal, Beck Erin, Klumpp-Thomas Carleen, Ceribelli Michele, Yin JuanJuan, Sowalsky Adam G, Price Douglas K, Chau Cindy H, Thomas Craig J, Figg William D

Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress

针对 ATR 的治疗可使具有高复制压力的小细胞肺癌产生持久的消退效果。

Anish Thomas ,Nobuyuki Takahashi ,Vinodh N Rajapakse ,Xiaohu Zhang ,Yilun Sun ,Michele Ceribelli ,Kelli M Wilson ,Yang Zhang ,Erin Beck ,Linda Sciuto ,Samantha Nichols ,Brian Elenbaas ,Janusz Puc ,Heike Dahmen ,Astrid Zimmermann ,Jillian Varonin ,Christopher W Schultz ,Sehyun Kim ,Hirity Shimellis ,Parth Desai ,Carleen Klumpp-Thomas ,Lu Chen ,Jameson Travers ,Crystal McKnight ,Sam Michael ,Zina Itkin ,Sunmin Lee ,Akira Yuno ,Min-Jung Lee ,Christophe E Redon ,Jessica D Kindrick ,Cody J Peer ,Jun S Wei ,Mirit I Aladjem ,William Douglas Figg ,Seth M Steinberg ,Jane B Trepel ,Frank T Zenke ,Yves Pommier ,Javed Khan ,Craig J Thomas

Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress

针对 ATR 的治疗可使具有高复制压力的小细胞肺癌产生持久的消退效果。

Anish Thomas,Nobuyuki Takahashi,Vinodh N Rajapakse,Xiaohu Zhang,Yilun Sun,Michele Ceribelli,Kelli M Wilson,Yang Zhang,Erin Beck,Linda Sciuto,Samantha Nichols,Brian Elenbaas,Janusz Puc,Heike Dahmen,Astrid Zimmermann,Jillian Varonin,Christopher W Schultz,Sehyun Kim,Hirity Shimellis,Parth Desai,Carleen Klumpp-Thomas,Lu Chen,Jameson Travers,Crystal McKnight,Sam Michael,Zina Itkin,Sunmin Lee,Akira Yuno,Min-Jung Lee,Christophe E Redon,Jessica D Kindrick,Cody J Peer,Jun S Wei,Mirit I Aladjem,William Douglas Figg,Seth M Steinberg,Jane B Trepel,Frank T Zenke,Yves Pommier,Javed Khan,Craig J Thomas  0

Adenosine A2A Receptor Activation Enhances Blood-Tumor Barrier Permeability in a Rodent Glioma Model

腺苷 A2A 受体激活可增强啮齿动物胶质瘤模型中的血肿瘤屏障通透性

Amélie Vézina, Monica Manglani, DreeAnna Morris, Brandon Foster, Matthew McCord, Hua Song, Meili Zhang, Dionne Davis, Wei Zhang, Jessica Bills, Kunio Nagashima, Priya Shankarappa, Jessica Kindrick, Stuart Walbridge, Cody J Peer, William D Figg, Mark R Gilbert, Dorian B McGavern, Leslie L Muldoon, Sa

Phase I/II Study of the Mesothelin-targeted Immunotoxin LMB-100 with Nab-Paclitaxel for Patients with Advanced Pancreatic Adenocarcinoma

间皮素靶向免疫毒素LMB-100联合白蛋白紫杉醇治疗晚期胰腺腺癌患者的I/II期研究

Alewine, Christine; Ahmad, Mehwish; Peer, Cody J; Hu, Zishuo I; Lee, Min-Jung; Yuno, Akira; Kindrick, Jessica D; Thomas, Anish; Steinberg, Seth M; Trepel, Jane B; Figg, William D; Hassan, Raffit; Pastan, Ira

Hypoxic Regulation of Gene Transcription and Chromatin: Cause and Effect

缺氧对基因转录和染色质的调控:原因和影响

Kindrick, Jessica D; Mole, David R

Metastasis-Specific Gene Expression in Autochthonous and Allograft Mouse Mammary Tumor Models: Stratification and Identification of Targetable Signatures

自体和同种异体移植小鼠乳腺肿瘤模型中转移特异性基因表达:分层和可靶向特征的鉴定

Ross, Christina; Szczepanek, Karol; Lee, Maxwell; Yang, Howard; Peer, Cody J; Kindrick, Jessica; Shankarappa, Priya; Lin, Zhi-Wei; Sanford, Jack D; Figg, William D; Hunter, Kent W

Local and Systemic Antitumor Effects of Photo-activatable Paclitaxel Prodrug on Rat Breast Tumor Models

光激活紫杉醇前药对大鼠乳腺肿瘤模型的局部和全身抗肿瘤作用

Bharathiraja Subramaniyan # ,Pallavi Rajaputra # ,Luong Nguyen ,Mengjie Li ,Cody J Peer ,Jessica Kindrick ,William D Figg ,Sukyung Woo ,Youngjae You