日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Monoclonal antibodies against nitrated nerve growth factor reveal an oxidation-dependent pathogenic hallmark in ALS

针对硝化神经生长因子的单克隆抗体揭示了肌萎缩侧索硬化症中一种氧化依赖性致病特征。

Varela, Valentina; Garcimartín, Santiago; Trias, Emiliano; Zeida, Ari; Richter, Monique; de León, Andrés; Miquel, Ernesto; King, Peter H; Vulliez-Le Normand, Brigitte; Martinez, Mariano; Alzari, Pedro M; Bartesaghi, Silvina; Radi, Rafael; Barbeito, Luis

Late-Stage Skeletal Muscle Transcriptome in Duchenne Muscular Dystrophy Shows a BMP4-Induced Molecular Signature

杜氏肌营养不良症晚期骨骼肌转录组显示出BMP4诱导的分子特征

Sothers, Hanna; Hu, Xianzhen; Crossman, David K; Si, Ying; Alexander, Matthew S; McDonald, Merry-Lynn N; King, Peter H; Lopez, Michael A

Myeloid-specific tristetraprolin mitigates postsurgical incisional pain by suppressing proinflammatory responses.

髓系特异性三四脯氨酸通过抑制促炎反应来减轻术后切口疼痛。

Guha Abhishek, Sorge Robert E, Si Ying, Smith Reed, Baig Sohail M, Husain Mohammed Amir, Totsch Stacie K, Piper Ava M, Blackshear Perry J, King Peter H

Inhibition of the RNA Regulator HuR Mitigates Spinal Cord Injury by Potently Suppressing Post-Injury Neuroinflammation.

抑制 RNA 调节因子 HuR 可有效抑制损伤后神经炎症,从而减轻脊髓损伤

Husain Mohammed Amir, Smith Reed, Sorge Robert E, Kaimari Abdulraheem, Si Ying, Hassan Ali Z, Guha Abhishek, Smith Katherine A, Cardozo Christopher P, DeBerry Jennifer J, Andrabi Shaida A, Nabors L Burt, Filippova Natalia, Webb Caroline K, King Peter H

The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity

肌细胞因子FGF21与ALS患者的生存率提高有关,并能减轻应激诱导的细胞毒性。

Guha, Abhishek; Si, Ying; Smith, Reed; Singh, Brijesh K; Zogu, Benisa; Yadav, Angad; Smith, Katherine A; Kazamel, Mohamed; Jiang, Nan; Ho, Ritchie; Thalacker-Mercer, Anna; Andrabi, Shaida A; Da Silva Pereira, Joao D Tavares; Salgado, Juliana S; Agrawal, Manasi; Velic, Emina Horvat; King, Peter H

Pilot Screening of TREM1 Inhibitors in Cell-Based Reporter Assays Reflecting TREM1/DAP12 Receptor Assembly and Functionality

在反映TREM1/DAP12受体组装和功能的基于细胞的报告基因检测中对TREM1抑制剂进行初步筛选

Filippova, Natalia; Hromov, Roman; Shi, James; King, Peter H; Nabors, Louis B

Quantitative effects of mechanical cardiopulmonary resuscitation devices in rural American emergency medical services: a retrospective cohort study

美国农村急救医疗服务中机械式心肺复苏装置的定量效应:一项回顾性队列研究

King, Peter H; Bahalkeh, Esmaeil

Myeloid-specific Tristetraprolin mitigates postsurgical incisional pain by suppressing proinflammatory responses.

髓系特异性Tristetraprolin通过抑制促炎反应来减轻术后切口疼痛。

Guha Abhishek, Sorge Robert E, Si Ying, Smith Reed, Baig Sohail M, Husain Mohammed Amir, Totsch Stacie K, Piper Ava M, Blackshear Perry J, King Peter H

The versatile role of HuR in Glioblastoma and its potential as a therapeutic target for a multi-pronged attack

HuR在胶质母细胞瘤中发挥着多重作用,并有望成为多管齐下攻击的治疗靶点。

Guha, Abhishek; Waris, Saboora; Nabors, Louis B; Filippova, Natalia; Gorospe, Myriam; Kwan, Thaddaeus; King, Peter H

SRI-42127, a novel small molecule inhibitor of the RNA regulator HuR, potently attenuates glial activation in a model of lipopolysaccharide-induced neuroinflammation

SRI-42127 是一种新型小分子 RNA 调节因子 HuR 抑制剂,可有效减弱脂多糖诱导的神经炎症模型中的胶质细胞活化。

Chellappan, Rajeshwari; Guha, Abhishek; Si, Ying; Kwan, Thaddaeus; Nabors, Louis B; Filippova, Natalia; Yang, Xiuhua; Myneni, Anish S; Meesala, Shriya; Harms, Ashley S; King, Peter H