日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lentivector-mediated SMN replacement in a mouse model of spinal muscular atrophy

在脊髓性肌萎缩症小鼠模型中,慢病毒载体介导的SMN替代疗法

Azzouz, Mimoun; Le, Thanh; Ralph, G Scott; Walmsley, Lucy; Monani, Umrao R; Lee, Debbie C P; Wilkes, Fraser; Mitrophanous, Kyriacos A; Kingsman, Susan M; Burghes, Arthur H M; Mazarakis, Nicholas D

Efficient production of germline transgenic chickens using lentiviral vectors

利用慢病毒载体高效生产种系转基因鸡

McGrew, Michael J; Sherman, Adrian; Ellard, Fiona M; Lillico, Simon G; Gilhooley, Hazel J; Kingsman, Alan J; Mitrophanous, Kyriacos A; Sang, Helen

Multicistronic lentiviral vector-mediated striatal gene transfer of aromatic L-amino acid decarboxylase, tyrosine hydroxylase, and GTP cyclohydrolase I induces sustained transgene expression, dopamine production, and functional improvement in a rat model of Parkinson's disease

利用多顺反子慢病毒载体介导的纹状体基因转移,将芳香族L-氨基酸脱羧酶、酪氨酸羟化酶和GTP环化水解酶I导入帕金森病大鼠模型,可诱导转基因的持续表达、多巴胺的产生以及功能改善。

Azzouz, Mimoun; Martin-Rendon, Enca; Barber, Robert D; Mitrophanous, Kyriacos A; Carter, Emma E; Rohll, Jonathan B; Kingsman, Susan M; Kingsman, Alan J; Mazarakis, Nicholas D

A Rev-independent human immunodeficiency virus type 1 (HIV-1)-based vector that exploits a codon-optimized HIV-1 gag-pol gene.

一种不依赖于 Rev 的人类免疫缺陷病毒 1 型 (HIV-1) 载体,利用密码子优化的 HIV-1 gag-pol 基因

Kotsopoulou E, Kim V N, Kingsman A J, Kingsman S M, Mitrophanous K A

Mutagenesis analysis of the murine leukemia virus matrix protein: identification of regions important for membrane localization and intracellular transport

鼠白血病病毒基质蛋白的诱变分析:鉴定对膜定位和细胞内转运至关重要的区域

Soneoka, Y; Kingsman, S M; Kingsman, A J

Cryo-electron microscopy structure of yeast Ty retrotransposon virus-like particles

酵母Ty逆转录转座子病毒样颗粒的冷冻电镜结构

Palmer, K J; Tichelaar, W; Myers, N; Burns, N R; Butcher, S J; Kingsman, A J; Fuller, S D; Saibil, H R

Structure-function studies of the human immunodeficiency virus type 1 matrix protein, p17

人类免疫缺陷病毒1型基质蛋白p17的结构-功能研究

Cannon, P M; Matthews, S; Clark, N; Byles, E D; Iourin, O; Hockley, D J; Kingsman, S M; Kingsman, A J

Induction of single and dual cytotoxic T-lymphocyte responses to viral proteins in mice using recombinant hybrid Ty-virus-like particles

利用重组杂交Ty病毒样颗粒在小鼠体内诱导针对病毒蛋白的单重和双重细胞毒性T淋巴细胞反应。

Layton, G T; Harris, S J; Myhan, J; West, D; Gotch, F; Hill-Perkins, M; Cole, J S; Meyers, N; Woodrow, S; French, T J; Adams, S E; Kingsman, A J

Murine leukemia virus-based Tat-inducible long terminal repeat replacement vectors: a new system for anti-human immunodeficiency virus gene therapy

基于鼠白血病病毒的Tat诱导型长末端重复序列替换载体:一种新型抗人类免疫缺陷病毒基因治疗系统

Cannon, P M; Kim, N; Kingsman, S M; Kingsman, A J

A transient three-plasmid expression system for the production of high titer retroviral vectors

用于生产高滴度逆转录病毒载体的瞬时三质粒表达系统

Soneoka, Y; Cannon, P M; Ramsdale, E E; Griffiths, J C; Romano, G; Kingsman, S M; Kingsman, A J