Immunization of Rhesus monkeys with a SialylTn-mAb17-1A conjugate vaccine co-formulated with QS-21 induces a temporary systemic cytokine release and NK cytotoxicity against tumor cells
用与QS-21共同配制的SialylTn-mAb17-1A结合疫苗免疫恒河猴,可诱导暂时性的全身性细胞因子释放和NK细胞对肿瘤细胞的细胞毒性。
期刊:Cancer Immunology Immunotherapy
影响因子:5.1
doi:10.1007/s00262-006-0231-x
Kircheis, Ralf; Siegl, Petra; Grunt, Susanne; Halanek, Nicole; Loibner, Hans; Mudde, Geert C; Nechansky, Andreas
肿瘤
肿瘤免疫
Rhesus
细胞生物学
肿瘤细胞
毒理研究
免疫/内分泌