Kirchhoff Paul D相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Discovery of ARD-2585 as an Exceptionally Potent and Orally Active PROTAC Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer.

发现 ARD-2585 是一种效力极强且口服有效的 PROTAC 雄激素受体降解剂，可用于治疗晚期前列腺癌

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.1c00900

Xiang Weiguo, Zhao Lijie, Han Xin, Qin Chong, Miao Bukeyan, McEachern Donna, Wang Yu, Metwally Hoda, Kirchhoff Paul D, Wang Lu, Matvekas Aleksas, He Miao, Wen Bo, Sun Duxin, Wang Shaomeng

发表日期：2021

文献求助收藏

Optimization of dipeptidic inhibitors of cathepsin L for improved Toxoplasma gondii selectivity and CNS permeability

优化组织蛋白酶L二肽抑制剂以提高弓形虫选择性和中枢神经系统渗透性

期刊:Bioorganic & Medicinal Chemistry Letters

影响因子:2.2

doi:10.1016/j.bmcl.2018.03.020

Zwicker, Jeffery D; Diaz, Nicolas A; Guerra, Alfredo J; Kirchhoff, Paul D; Wen, Bo; Sun, Duxin; Carruthers, Vern B; Larsen, Scott D

发表日期：2018

文献求助收藏

Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors

基于结构的G蛋白偶联受体激酶2抑制剂的设计、合成和生物学评价

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.5b02000

Waldschmidt, Helen V; Homan, Kristoff T; Cruz-Rodríguez, Osvaldo; Cato, Marilyn C; Waninger-Saroni, Jessica; Larimore, Kelly M; Cannavo, Alessandro; Song, Jianliang; Cheung, Joseph Y; Kirchhoff, Paul D; Koch, Walter J; Tesmer, John J G; Larsen, Scott D

发表日期：2016

文献求助收藏

Optimization of novel nipecotic bis(amide) inhibitors of the Rho/MKL1/SRF transcriptional pathway as potential anti-metastasis agents

优化新型尼泊酮类双(酰胺)抑制剂，以期通过Rho/MKL1/SRF转录通路发挥潜在的抗转移作用

期刊:Bioorganic & Medicinal Chemistry Letters

影响因子:2.2

doi:10.1016/j.bmcl.2013.04.080

Bell, Jessica L; Haak, Andrew J; Wade, Susan M; Kirchhoff, Paul D; Neubig, Richard R; Larsen, Scott D

发表日期：2013

文献求助收藏

Erratum: “Model for the fast estimation of basis set superposition error in biomolecular systems” [J. Chem. Phys. 135, 144110 (2011)]

勘误：“生物分子系统中基组叠加误差快速估计模型”[J. Chem. Phys. 135, 144110 (2011)]

期刊:Journal of Virology

影响因子:3.8

doi:10.1128/JVI.01671-14

Delekta, Phillip C; Dobry, Craig J; Sindac, Janice A; Barraza, Scott J; Blakely, Pennelope K; Xiang, Jianming; Kirchhoff, Paul D; Keep, Richard F; Irani, David N; Larsen, Scott D; Miller, David J; Kim, Jaegil; Straub, John E; Faver, John C; Zheng, Zheng; Merz, Kenneth M Jr

发表日期：2012

文献求助收藏

MScreen: an integrated compound management and high-throughput screening data storage and analysis system

MScreen：一个集成的化合物管理和高通量筛选数据存储与分析系统

doi:10.1177/1087057112450186

Jacob, Renju T; Larsen, Martha J; Larsen, Scott D; Kirchhoff, Paul D; Sherman, David H; Neubig, Richard R

多发性硬化症

发表日期：2012

文献求助收藏

Identification of thieno[3,2-b]pyrrole derivatives as novel small molecule inhibitors of neurotropic alphaviruses

噻吩并[3,2-b]吡咯衍生物作为新型嗜神经性甲病毒小分子抑制剂的鉴定

期刊:Journal of Infectious Diseases

影响因子:4.5

doi:10.1086/597275

Peng, Weiping; Peltier, Daniel C; Larsen, Martha J; Kirchhoff, Paul D; Larsen, Scott D; Neubig, Richard R; Miller, David J

发表日期：2009

文献求助收藏

Differences between high- and low-affinity complexes of enzymes and nonenzymes

酶和非酶的高亲和力复合物与低亲和力复合物之间的差异

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/jm8006504

Carlson, Heather A; Smith, Richard D; Khazanov, Nickolay A; Kirchhoff, Paul D; Dunbar, James B Jr; Benson, Mark L

发表日期：2008

文献求助收藏