HIT101308137 and HIT104293658 nominate dual target chemotypes for PTPN1 and PTPN2 with preliminary selectivity in colorectal cancer cells
HIT101308137 和 HIT104293658 是针对 PTPN1 和 PTPN2 的双靶点化学类型，在结直肠癌细胞中具有初步选择性。
期刊:Acta Crystallographica Section D-Structural Biology
影响因子:3.8
doi:10.1107/S2059798326002688
Koulas, Symeon; Bui, Soi; Kirkegaard, Julius B; Bourenkov, Gleb; Steiner, Roberto A; Chen, Ke; Xia, Mengdi; Li, Changhong; Ren, Zhenhua; Li, Xiaohui; Wu, Weiwei; Wang, Hui; Zhang, Luyao; Li, Danqing; Chen, Yuxiang; Lin, Bolin; Jiang, Huiqin; Meng, Ting; Zhu, Zheao; He, Lijun; Zhang, Hui; Liu, Hu; Zhang, Ruijie; Huang, Chaojie; Chen, Jingyun; Chen, Rui; Cao, Liping
