日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Editorial Expression of Concern: The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice

编辑关注声明：黄酮类化合物原花青素C1具有延缓衰老活性，并能延长小鼠寿命。

期刊:Nature Metabolism
影响因子:20.8
doi:10.1038/s42255-026-01487-y
Xu, Qixia; Fu, Qiang; Li, Zi; Liu, Hanxin; Wang, Ying; Lin, Xu; He, Ruikun; Zhang, Xuguang; Ju, Zhenyu; Campisi, Judith; Kirkland, James L; Sun, Yu
衰老
发表日期：2026
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Senolytics, dasatanib plus quercetin, reduce kidney inflammation, senescent cell abundance, and injury while restoring geroprotective factors in murine diabetic kidney disease.

衰老细胞清除剂达沙替尼加槲皮素可减少小鼠糖尿病肾病中的肾脏炎症、衰老细胞数量和损伤，同时恢复抗衰老因子。

期刊:EBioMedicine
影响因子:10.8
doi:10.1016/j.ebiom.2026.106124
Bian Xiaohui, Snow Zachary K, Zinn Caroline J, Bratulin Anastasia L, Elhusseiny Khaled M, Tchkonia Tamar, Kirkland James L, Zhu Yi, Khosla Sundeep, Kim Seo Rin, Lerman Lilach O, Hickson LaTonya J
糖尿病
衰老
糖尿病肾病
细胞生物学
Immunology/Inflammation
炎症
发表日期：2026
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Senotherapeutics for metabolic disease and diabetic complications

用于代谢性疾病和糖尿病并发症的敏感疗法

期刊:Journal of Internal Medicine
影响因子:9.2
doi:10.1111/joim.70039
Palmer, Allyson K; Spinelli, Rosa; Prata, Larissa G Langhi; Chaib, Selim; Suda, Masayoshi; Tchkonia, Tamar; Smith, Ulf; Kirkland, James L
糖尿病
代谢
发表日期：2026
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Spatial Reorganization of Chromatin Architecture Shapes the Expression Phenotype of Therapy-Induced Senescent Cells

染色质结构的空间重组塑造了治疗诱导衰老细胞的表达表型

期刊:Aging Cell
影响因子:7.1
doi:10.1111/acel.70366
Zhang, Ge; Zhang, Wei; Wang, Changxu; Jiang, Zhirui; Xu, Qixia; Li, Haipeng; Kirkland, James L; Wei, Gang; Sun, Yu
细胞生物学
衰老
发表日期：2026
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Senolytic-Resistant Senescent Cells Have a Distinct SASP Profile and Functional Impact: The Path to Developing Senosensitizers.

抗衰老细胞具有独特的 SASP 特征和功能影响：开发衰老增敏剂的途径。

期刊:Aging Cell
影响因子:7.1
doi:10.1111/acel.70358
Tripathi Utkarsh, Suda Masayoshi, Kulshreshtha Vagisha, Piatkowski Bryan T, Palmer Allyson K, Giorgadze Nino, Inman Christina, Gasek Nathan, Xu Ming, Johnson Kurt O, Pirtskhalava Tamar, Chaib Selim, Langhi Prata Larissa P G, Zhu Yi, Kandhaya-Pillai Renuka, Tullius Stefan G, Wyles Saranya P, Majji Rambabu, Yalamanchili Hari Krishna, Allison David B, Tchkonia Tamar, Kirkland James L
衰老
细胞生物学
发表日期：2026
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Rare heterozygous de novo variants in RAPGEF2 are associated with a neurodevelopmental disorder

RAPGEF2基因中罕见的杂合新生变异与神经发育障碍相关。

期刊:Genetics in Medicine
影响因子:6.2
doi:10.1016/j.gim.2026.101685
Bereshneh, Ali H; Wilson, Kirkland A; Pan, Xueyang; Hannan, Shabab B; Cooper, Megan A; Diaz, Jullianne; Leon, Eyby; Moses, Tiana M; Azamian, Mahshid S; Scott, Daryl A; Billie Au, Ping Yee; Appendino, Juan Pablo; Scheffer, Ingrid E; Kaspi, Antony; Bahlo, Melanie; Hildebrand, Michael S; Morgan, Angela T; Ekure, Ekanem; Shulman, Joshua M; Hildebrandt, Friedhelm; Posey, Jennifer E; Kruszka, Paul; Vilain, Eric; Yamamoto, Shinya; Kanca, Oguz; Berger, Seth; Bellen, Hugo J
发育与干细胞
神经科学
发表日期：2026
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Fisetin-Mediated Topical Modulation of Senescent Cells in Skin Improves Wound Healing Dynamics in Diabetic Mice.

非瑟酮介导的皮肤衰老细胞局部调节可改善糖尿病小鼠的伤口愈合动力学。

期刊:Advances in Wound Care
影响因子:5.6
doi:10.1177/21621918261426580
Numani Asfia, Carrasco-Jeldres Margarita, Hernandez-Rovira Barbara, Purushothaman K-Raman, Melin Matthew M, Kirkland James L, Wyles Saranya
糖尿病
衰老
细胞生物学
发表日期：2026
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Engineering Stem Cells for Islet Replacement Therapy: Recent Advances and Barriers for Clinical Translation

工程化干细胞用于胰岛替代疗法：最新进展及临床转化障碍

期刊:Cells
影响因子:5.2
doi:10.3390/cells15060532
Kuncha, Jayachandra; Veeraswamy, Sharmila Devi; Darden, Carly M; Kirkland, Jeffrey; Lawrence, Michael C; Danobeitia, Juan S; Naziruddin, Bashoo
细胞生物学
发育与干细胞
干细胞
发表日期：2026
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Frequency and Predictors of Adolescent Worry for School Gun Violence in the United States: Findings From a Nationally Representative Study

美国青少年对校园枪支暴力担忧的频率和预测因素：一项具有全国代表性的研究结果

期刊:Journal of Adolescent Health
影响因子:4.5
doi:10.1016/j.jadohealth.2025.09.007
Kirkland, Danielle; Fu, Tsung-Chieh; Herbenick, Debby; Hensel, Devon J
发表日期：2026
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A phase II randomized placebo-controlled study of fisetin to improve physical function in breast cancer survivors: the TROFFi study rationale and trial design

一项评估非瑟酮改善乳腺癌幸存者身体功能的II期随机安慰剂对照研究：TROFFi研究的理论依据和试验设计

期刊:Therapeutic Advances in Medical Oncology
影响因子:4.2
doi:10.1177/17588359261424668
Ji, Jingran; Crespi, Catherine M; Yee, Lisa; Zekster, Yuliya A; Al-Saleem, Ali; Petersen, Laura; Lee, Catherine; Son, Nala; Smith, Claire; Evans, Tamara; Tchkonia, Tamar; Kirkland, James L; Kuchel, George A; Cohen, Harvey Jay; Sedrak, Mina S
肿瘤
肿瘤免疫
乳腺癌
发表日期：2026
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