Intranasally Administered EVs from hiPSC-derived NSCs Alter the Transcriptomic Profile of Activated Microglia and Conserve Brain Function in an Alzheimer's Model
鼻内给药的源自hiPSC的神经干细胞来源的细胞外囊泡可改变活化小胶质细胞的转录组谱，并在阿尔茨海默病模型中维持脑功能。
期刊:
影响因子:
doi:10.1101/2024.01.18.576313
Madhu, Leelavathi N; Kodali, Maheedhar; Upadhya, Raghavendra; Rao, Shama; Shuai, Bing; Somayaji, Yogish; Attaluri, Sahithi; Kirmani, Maha; Gupta, Shreyan; Maness, Nathaniel; Rao, Xiaolan; Cai, James; Shetty, Ashok K
细胞生物学
发育与干细胞
神经科学
胶质细胞
阿尔茨海默症
囊泡
干细胞
