日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Design, synthesis, and molecular modeling of novel pyrido[2,3-d]pyrimidine analogues as antifolates; application of Buchwald-Hartwig aminations of heterocycles

新型吡啶并[2,3-d]嘧啶类似物作为抗叶酸剂的设计、合成和分子建模；杂环化合物的Buchwald-Hartwig胺化反应的应用

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm400086g
Gangjee, Aleem; Namjoshi, Ojas A; Raghavan, Sudhir; Queener, Sherry F; Kisliuk, Roy L; Cody, Vivian
发表日期：2013
文献求助 收藏

Design, synthesis, and X-ray crystal structure of classical and nonclassical 2-amino-4-oxo-5-substituted-6-ethylthieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agents.

设计、合成经典和非经典 2-氨基-4-氧代-5-取代-6-乙基噻吩并[2,3-d]嘧啶类化合物，并研究其作为双重胸苷酸合成酶和二氢叶酸还原酶抑制剂及潜在抗肿瘤药物的 X 射线晶体结构

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm900490a
Gangjee Aleem, Li Wei, Kisliuk Roy L, Cody Vivian, Pace Jim, Piraino Jennifer, Makin Jennifer
肿瘤
发表日期：2009
文献求助 收藏

Dual inhibitors of thymidylate synthase and dihydrofolate reductase as antitumor agents: design, synthesis, and biological evaluation of classical and nonclassical pyrrolo[2,3-d]pyrimidine antifolates(1).

胸苷酸合成酶和二氢叶酸还原酶的双重抑制剂作为抗肿瘤药物：经典和非经典吡咯并[2,3-d]嘧啶抗叶酸的设计、合成和生物学评价(1)

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm058276a
Gangjee Aleem, Jain Hiteshkumar D, Phan Jaclyn, Lin Xin, Song Xiaohong, McGuire John J, Kisliuk Roy L
肿瘤
发表日期：2006
文献求助 收藏

Synthesis of classical, four-carbon bridged 5-substituted furo[2,3-d]pyrimidine and 6-substituted pyrrolo[2,3-d]pyrimidine analogues as antifolates

经典四碳桥联5-取代呋喃并[2,3-d]嘧啶和6-取代吡咯并[2,3-d]嘧啶类似物作为抗叶酸的合成

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm058213s
Gangjee, Aleem; Zeng, Yibin; McGuire, John J; Kisliuk, Roy L
发表日期：2005
文献求助 收藏