日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Decision-Making Criteria and Methods for Initiating Late-Stage Clinical Trials in Drug Development From a Multi-Stakeholder Perspective: A Scoping Review

从多方利益相关者的角度探讨启动药物研发后期临床试验的决策标准和方法:一项范围界定综述

Jiang, Ce; Beji, Céline; Zebachi, Sonia; Hayek, Ghinwa Y; Cetinyurek-Yavuz, Aysun; Fayyad, Muhammad Bergas N; Rodwell, Laura; Roes, Kit C B; Amzal, Billy; Gerlinger, Christoph; Porcher, Raphaël; Tanniou, Julien

Optimizing Patient Registries for Regulatory Decision Making - Key Learnings From an HMA/EMA Multistakeholder Workshop

优化患者登记系统以辅助监管决策——HMA/EMA多方利益相关者研讨会的主要经验总结

Plueschke, Kelly; Jonker, Carla; Kankanen, Hanna; Vetter, Thorsten; Sepodes, Bruno; Naehrlich, Lutz; Hillert, Jan; Crane, Gracy; Straus, Sabine; Foggi, Paolo; Martin, Simona; Kyriakopoulou, Christina; Mol, Peter; Day, Francesca; Breen, Kieran; Bennett, Neil; de Lemus Belmonte, Mencia; Bennett, Simon; Verpillat, Patrice; Roes, Kit C B; Cochino, Ana; Schaefer, Franz; Hernández-Rivas, Jesús María; McGettigan, Patricia; Arlett, Peter

On the Two-Step Hybrid Design for Augmenting Randomized Trials Using Real-World Data

利用真实世界数据增强随机试验的两步混合设计

Xu, Jiapeng; van Eijk, Ruben P A; Ellis, Alicia; Pan, Tianyu; Nelson, Lorene M; Roes, Kit C B; van Dijk, Marc; Sarno, Maria; van den Berg, Leonard H; Tian, Lu; Lu, Ying

Estimation of the Restricted Mean Duration of Response (RMDoR) in Oncology

肿瘤学中限制性平均反应持续时间 (RMDoR) 的估计

Daletzakis, Antonios; Roes, Kit C B; Jonker, Marianne A

Revisiting the impact of Schistosoma mansoni regulating mechanisms on transmission dynamics using SchiSTOP, a novel modelling framework

利用新型建模框架 SchiSTOP,重新审视曼氏血吸虫调控机制对传播动力学的影响

Malizia, Veronica; de Vlas, Sake J; Roes, Kit C B; Giardina, Federica

In silico cancer immunotherapy trials uncover the consequences of therapy-specific response patterns for clinical trial design and outcome

计算机模拟癌症免疫疗法试验揭示了治疗特异性反应模式对临床试验设计和结果的影响。

Creemers, Jeroen H A; Ankan, Ankur; Roes, Kit C B; Schröder, Gijs; Mehra, Niven; Figdor, Carl G; de Vries, I Jolanda M; Textor, Johannes

TUBectomy with delayed oophorectomy as an alternative to risk-reducing salpingo-oophorectomy in high-risk women to assess the safety of prevention: the TUBA-WISP II study protocol

对于高危女性,以输卵管切除术联合延迟卵巢切除术替代风险降低型输卵管卵巢切除术,以评估预防安全性:TUBA-WISP II 研究方案

Steenbeek, Miranda P; van Bommel, Majke H D; intHout, Joanna; Peterson, Christine B; Simons, Michiel; Roes, Kit C B; Kets, Marleen; Norquist, Barbara M; Swisher, Elizabeth M; Hermens, Rosella P M G; Lu, Karen H; de Hullu, Joanne A

Randomized double-blind placebo-controlled crossover trial with pyridostigmine in spinal muscular atrophy types 2-4

吡啶斯的明治疗脊髓性肌萎缩症2-4型的随机双盲安慰剂对照交叉试验

Stam, Marloes; Wijngaarde, Camiel A; Bartels, Bart; Asselman, Fay-Lynn; Otto, Louise A M; Habets, Laura E; van Eijk, Ruben P A; Middelkoop, Bas M; Goedee, H Stephan; de Groot, Janke F; Roes, Kit C B; Schoenmakers, Marja A G C; Nieuwenhuis, Edward E S; Cuppen, Inge; van den Berg, Leonard H; Wadman, Renske I; van der Pol, W Ludo

The Trial within Cohorts (TwiCs) study design in oncology: experience and methodological reflections

肿瘤学中的队列内试验(TwiCs)研究设计:经验和方法论反思

Kessels, Rob; May, Anne M; Koopman, Miriam; Roes, Kit C B

The STEPWISE study: study protocol for a smartphone-based exercise solution for people with Parkinson's Disease (randomized controlled trial)

STEPWISE 研究:针对帕金森病患者的基于智能手机的运动解决方案的研究方案(随机对照试验)

Schootemeijer, Sabine; de Vries, Nienke M; Macklin, Eric A; Roes, Kit C B; Joosten, Hilde; Omberg, Larsson; Ascherio, Alberto; Schwarzschild, Michael A; Bloem, Bastiaan R