日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Nutritional L-Citrulline and Tetrahydrobiopterin in Peripheral Artery Disease: A Phase II Randomized Trial (CIPER Study)

营养性 L-瓜氨酸和四氢生物蝶呤治疗外周动脉疾病：一项 II 期随机试验（CIPER 研究）

期刊:JACC Advances
影响因子:
doi:10.1016/j.jacadv.2025.101590
Sedding, Daniel; Schmidt, Tim M; Bähre, Heike; Bavendiek, Udo; Casas, Ana I; Chen, Suzi; Thao-Vi Dao, Vu; Elbatreek, Mahmoud H; Gutzki, Frank; Hahn, Andreas; Kleikers, Pamela; Krahn, Thomas; Macchiusi, Cecilia; Martin, Catherine; Mucke, Hermann; Nogales, Cristian; Schmidt, Beate M L; Seifert, Roland; Sonnenschein, Kristina; Tongers, Jörn; Thol, Jens; van der Arend, Inés; van Kuijk, Sander M J; Wingler, Kirstin; Wu, Michael; Bauersachs, Johann; McGrath, Barry; Schmidt, Harald H H W
发表日期：2025
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Un-biased housekeeping gene panel selection for high-validity gene expression analysis

无偏倚的管家基因面板选择，用于高有效性的基因表达分析

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-022-15989-8
Casas, Ana I; Hassan, Ahmed A; Manz, Quirin; Wiwie, Christian; Kleikers, Pamela; Egea, Javier; López, Manuela G; List, Markus; Baumbach, Jan; Schmidt, Harald H H W
发表日期：2022
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Endothelial reactive oxygen-forming NADPH oxidase 5 is a possible player in diabetic aortic aneurysm but not atherosclerosis

内皮活性氧形成 NADPH 氧化酶 5 可能是糖尿病主动脉瘤的诱因，但不是动脉粥样硬化的诱因

期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-022-15706-5
Florence Ho #, Anna M D Watson #, Mahmoud H Elbatreek #, Pamela W M Kleikers, Waheed Khan, Karly C Sourris, Aozhi Dai, Jay Jha, Harald H H W Schmidt, Karin A M Jandeleit-Dahm
代谢
心血管
动脉瘤
动脉粥样硬化
糖尿病
发表日期：2022
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NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype

NOX5 诱导的内皮 NO 合酶解偶联是年龄相关性高血压内型的致病机制和诊断靶点

期刊:PLoS Biology
影响因子:7.8
doi:10.1371/journal.pbio.3000885
Mahmoud H Elbatreek, Sepideh Sadegh, Elisa Anastasi, Emre Guney, Cristian Nogales, Tim Kacprowski, Ahmed A Hassan, Andreas Teubner, Po-Hsun Huang, Chien-Yi Hsu, Paul M H Schiffers, Ger M Janssen, Pamela W M Kleikers, Anil Wipat, Jan Baumbach, Jo G R De Mey, Harald H H W Schmidt
心血管
高血压
发表日期：2020
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From single drug targets to synergistic network pharmacology in ischemic stroke

从单一药物靶点到缺血性卒中的协同网络药理学

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1820799116
Casas, Ana I; Hassan, Ahmed A; Larsen, Simon J; Gomez-Rangel, Vanessa; Elbatreek, Mahmoud; Kleikers, Pamela W M; Guney, Emre; Egea, Javier; López, Manuela G; Baumbach, Jan; Schmidt, Harald H H W
发表日期：2019
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A diseasome cluster-based drug repurposing of soluble guanylate cyclase activators from smooth muscle relaxation to direct neuroprotection

基于疾病组簇的可溶性鸟苷酸环化酶激活剂药物再利用，从平滑肌松弛到直接神经保护

期刊:npj Systems Biology and Applications
影响因子:3.5
doi:10.1038/s41540-017-0039-7
Friederike Langhauser #, Ana I Casas #, Vu-Thao-Vi Dao, Emre Guney, Jörg Menche, Eva Geuss, Pamela W M Kleikers, Manuela G López, Albert-L Barabási, Christoph Kleinschnitz #, Harald H H W Schmidt #
神经
发表日期：2018
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NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage

NOX4依赖性神经元自毒性和血脑屏障破坏解释了大脑对缺血性损伤的超强敏感性。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1705034114
Casas, Ana I; Geuss, Eva; Kleikers, Pamela W M; Mencl, Stine; Herrmann, Alexander M; Buendia, Izaskun; Egea, Javier; Meuth, Sven G; Lopez, Manuela G; Kleinschnitz, Christoph; Schmidt, Harald H H W
血脑屏障
NOX4
毒理研究
神经科学
发表日期：2017
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NOS knockout or inhibition but not disrupting PSD-95-NOS interaction protect against ischemic brain damage

NOS 敲除或抑制但不破坏 PSD-95-NOS 相互作用可防止缺血性脑损伤

期刊:Journal of Cerebral Blood Flow and Metabolism
影响因子:4.9
doi:10.1177/0271678X16657094
Christoph Kleinschnitz, Stine Mencl, Pamela W M Kleikers, Michael K Schuhmann, Manuela G López, Ana I Casas, Bilge Sürün, Andreas Reif, Harald H H W Schmidt
神经科学
发表日期：2016
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Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

NADPH氧化酶抑制剂的演变：选择性和靶点结合机制

期刊:Antioxidants & Redox Signaling
影响因子:6.1
doi:10.1089/ars.2013.5814
Altenhöfer, Sebastian; Radermacher, Kim A; Kleikers, Pamela W M; Wingler, Kirstin; Schmidt, Harald H H W
发表日期：2015
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A combined pre-clinical meta-analysis and randomized confirmatory trial approach to improve data validity for therapeutic target validation

采用临床前荟萃分析和随机验证性试验相结合的方法，以提高治疗靶点验证的数据有效性

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/srep13428
Kleikers, Pamela W M; Hooijmans, Carlijn; Göb, Eva; Langhauser, Friederike; Rewell, Sarah S J; Radermacher, Kim; Ritskes-Hoitinga, Merel; Howells, David W; Kleinschnitz, Christoph; Schmidt, Harald H H W
发表日期：2015
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