Interferon-gamma sensitizes resistant Ewing's sarcoma cells to tumor necrosis factor apoptosis-inducing ligand-induced apoptosis by up-regulation of caspase-8 without altering chemosensitivity
干扰素-γ通过上调caspase-8,使耐药的尤文氏肉瘤细胞对肿瘤坏死因子凋亡诱导配体诱导的细胞凋亡更加敏感,而不改变其化疗敏感性。
期刊:American Journal of Pathology
影响因子:3.6
doi:10.2353/ajpath.2007.060993
Lissat, Andrej; Vraetz, Thomas; Tsokos, Maria; Klein, Ruth; Braun, Matthias; Koutelia, Nino; Fisch, Paul; Romero, Maria E; Long, Lauren; Noellke, Peter; Mackall, Crystal L; Niemeyer, Charlotte M; Kontny, Udo