日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Author Correction: Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons

作者更正：TDP-43 C端片段的凝胶状包涵体可隔离神经元中停滞的蛋白酶体。

期刊:EMBO Reports
影响因子:6.2
doi:10.1038/s44319-024-00163-0
Riemenschneider, Henrick; Guo, Qiang; Bader, Jakob; Frottin, Frédéric; Farny, Daniel; Kleinberger, Gernot; Haass, Christian; Mann, Matthias; Hartl, F Ulrich; Baumeister, Wolfgang; Hipp, Mark S; Meissner, Felix; Fernández-Busnadiego, Rubén; Edbauer, Dieter
神经科学
发表日期：2024
文献求助 收藏

Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study

脑脊液中可溶性TREM2及其与常染色体显性遗传阿尔茨海默病患者其他生物标志物和认知功能的关系：一项纵向观察研究

期刊:Lancet Neurology
影响因子:45.5
doi:10.1016/S1474-4422(22)00027-8
Morenas-Rodríguez, Estrella; Li, Yan; Nuscher, Brigitte; Franzmeier, Nicolai; Xiong, Chengjie; Suárez-Calvet, Marc; Fagan, Anne M; Schultz, Stephanie; Gordon, Brian A; Benzinger, Tammie L S; Hassenstab, Jason; McDade, Eric; Feederle, Regina; Karch, Celeste M; Schlepckow, Kai; Morris, John C; Kleinberger, Gernot; Nellgard, Bengt; Vöglein, Jonathan; Blennow, Kaj; Zetterberg, Henrik; Ewers, Michael; Jucker, Mathias; Levin, Johannes; Bateman, Randall J; Haass, Christian
阿尔茨海默症
神经科学
TREM2
发表日期：2022
文献求助 收藏

Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition

慢性PPARγ刺激使淀粉样变性向更高纤维化程度转变，但改善认知功能

期刊:Frontiers in Aging Neuroscience
影响因子:4.5
doi:10.3389/fnagi.2022.854031
Blume, Tanja; Deussing, Maximilian; Biechele, Gloria; Peters, Finn; Zott, Benedikt; Schmidt, Claudio; Franzmeier, Nicolai; Wind, Karin; Eckenweber, Florian; Sacher, Christian; Shi, Yuan; Ochs, Katharina; Kleinberger, Gernot; Xiang, Xianyuan; Focke, Carola; Lindner, Simon; Gildehaus, Franz-Josef; Beyer, Leonie; von Ungern-Sternberg, Barbara; Bartenstein, Peter; Baumann, Karlheinz; Adelsberger, Helmuth; Rominger, Axel; Cumming, Paul; Willem, Michael; Dorostkar, Mario M; Herms, Jochen; Brendel, Matthias
神经科学
发表日期：2022
文献求助 收藏

Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation

治疗前小胶质细胞活化和性别决定慢性免疫调节的治疗效果

期刊:Theranostics
影响因子:13.3
doi:10.7150/thno.64022
Biechele, Gloria; Blume, Tanja; Deussing, Maximilian; Zott, Benedikt; Shi, Yuan; Xiang, Xianyuan; Franzmeier, Nicolai; Kleinberger, Gernot; Peters, Finn; Ochs, Katharina; Focke, Carola; Sacher, Christian; Wind, Karin; Schmidt, Claudio; Lindner, Simon; Gildehaus, Franz-Josef; Eckenweber, Florian; Beyer, Leonie; von Ungern-Sternberg, Barbara; Bartenstein, Peter; Baumann, Karlheinz; Dorostkar, Mario M; Rominger, Axel; Cumming, Paul; Willem, Michael; Adelsberger, Helmuth; Herms, Jochen; Brendel, Matthias
胶质细胞
细胞生物学
免疫/内分泌
发表日期：2021
文献求助 收藏

Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration

脑脊液中sTREM2水平升高可降低ApoE4相关的认知衰退和神经退行性疾病风险。

期刊:Molecular Neurodegeneration
影响因子:17.5
doi:10.1186/s13024-020-00407-2
Franzmeier, Nicolai; Suárez-Calvet, M; Frontzkowski, Lukas; Moore, Annah; Hohman, Timothy J; Morenas-Rodriguez, Estrella; Nuscher, Brigitte; Shaw, Leslie; Trojanowski, John Q; Dichgans, Martin; Kleinberger, Gernot; Haass, Christian; Ewers, Michael
TREM2
神经科学
发表日期：2020
文献求助 收藏

Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation

脑脊液中sTREM2水平升高和微胶质细胞活化与β-淀粉样蛋白积累速度减慢相关。

期刊:EMBO Molecular Medicine
影响因子:8.3
doi:10.15252/emmm.202012308
Ewers, Michael; Biechele, Gloria; Suárez-Calvet, Marc; Sacher, Christian; Blume, Tanja; Morenas-Rodriguez, Estrella; Deming, Yuetiva; Piccio, Laura; Cruchaga, Carlos; Kleinberger, Gernot; Shaw, Leslie; Trojanowski, John Q; Herms, Jochen; Dichgans, Martin; Brendel, Matthias; Haass, Christian; Franzmeier, Nicolai
胶质细胞
细胞生物学
神经科学
TREM2
发表日期：2020
文献求助 收藏

Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid-β pathology.

阿尔茨海默病早期脑脊液 sTREM2 的增加与 tau 蛋白相关的神经退行性变有关，但与淀粉样蛋白-β 病理无关

期刊:Molecular Neurodegeneration
影响因子:17.5
doi:10.1186/s13024-018-0301-5
Suárez-Calvet Marc, Morenas-Rodríguez Estrella, Kleinberger Gernot, Schlepckow Kai, Araque Caballero Miguel Ángel, Franzmeier Nicolai, Capell Anja, Fellerer Katrin, Nuscher Brigitte, Eren Erden, Levin Johannes, Deming Yuetiva, Piccio Laura, Karch Celeste M, Cruchaga Carlos, Shaw Leslie M, Trojanowski John Q, Weiner Michael, Ewers Michael, Haass Christian
神经科学
发表日期：2019
文献求助 收藏

An Alzheimer-associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function

一种与阿尔茨海默病相关的TREM2变异发生在ADAM切割位点，并影响其脱落和吞噬功能。

期刊:EMBO Molecular Medicine
影响因子:8.3
doi:10.15252/emmm.201707672
Schlepckow, Kai; Kleinberger, Gernot; Fukumori, Akio; Feederle, Regina; Lichtenthaler, Stefan F; Steiner, Harald; Haass, Christian
阿尔茨海默症
TREM2
ADA
发表日期：2017
文献求助 收藏

The APOE ε4 genotype modulates CSF YKL-40 levels and their structural brain correlates in the continuum of Alzheimer's disease but not those of sTREM2

APOE ε4 基因型调节脑脊液 YKL-40 水平及其与阿尔茨海默病连续谱中脑结构相关性的变化，但与 sTREM2 无关。

期刊:Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring
影响因子:4.4
doi:10.1016/j.dadm.2016.12.002
Gispert, Juan Domingo; Monté, Gemma C; Suárez-Calvet, Marc; Falcon, Carles; Tucholka, Alan; Rojas, Santiago; Rami, Lorena; Sánchez-Valle, Raquel; Lladó, Albert; Kleinberger, Gernot; Haass, Christian; Molinuevo, José Luis
阿尔茨海默症
TREM2
神经科学
YKL-40
APOE
发表日期：2017
文献求助 收藏

Early changes in CSF sTREM2 in dominantly inherited Alzheimer's disease occur after amyloid deposition and neuronal injury

显性遗传性阿尔茨海默病中脑脊液 sTREM2 的早期变化发生在淀粉样蛋白沉积和神经元损伤之后。

期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.aag1767
Suárez-Calvet, Marc; Araque Caballero, Miguel Ángel; Kleinberger, Gernot; Bateman, Randall J; Fagan, Anne M; Morris, John C; Levin, Johannes; Danek, Adrian; Ewers, Michael; Haass, Christian
阿尔茨海默症
神经科学
TREM2
发表日期：2016
文献求助 收藏