Klement John D相关文献与解析，生知库 | 链接生命科学的每一步

Czabala, Patrick; Zhao, Yang; Klement, John D; Redd, Priscilla S; Poschel, Dakota; Carver, Kristen; Fick, Kendra; Tiamiyu, Zainab; Zoccheddu, Martina; Schoenlein, Patricia V; Waller, Jennifer; Shi, Huidong; Liu, Kebin

肿瘤

肠癌

肿瘤免疫

发表日期：2026

文献求助收藏

STAT5 Activation Enhances Adoptive Therapy Combined with Peptide Vaccination by Preventing PD-1 Inhibition.

STAT5 激活通过阻止 PD-1 抑制来增强过继疗法与肽疫苗联合应用的效果

期刊:Molecular Cancer Therapeutics

影响因子:5.5

doi:10.1158/1535-7163.MCT-24-0505

Fan Aaron E, Sultan Hussein, Kumai Takumi, Fesenkova Valentyna I, Wu Juan, Klement John D, Bernstock Joshua D, Friedman Gregory K, Celis Esteban

信号转导

发表日期：2025

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Osteopontin Blockade Immunotherapy Increases Cytotoxic T Lymphocyte Lytic Activity and Suppresses Colon Tumor Progression

骨桥蛋白阻断免疫疗法可增强细胞毒性T淋巴细胞的溶解活性并抑制结肠肿瘤进展

期刊:Cancers

影响因子:4.4

doi:10.3390/cancers13051006

Klement, John D; Poschel, Dakota B; Lu, Chunwan; Merting, Alyssa D; Yang, Dafeng; Redd, Priscilla S; Liu, Kebin

MS4A1 expression and function in T cells in the colorectal cancer tumor microenvironment

MS4A1在结直肠癌肿瘤微环境中T细胞中的表达和功能

期刊:Cellular Immunology

影响因子:2.9

doi:10.1016/j.cellimm.2020.104260

Mudd, T William Jr; Lu, Chunwan; Klement, John D; Liu, Kebin

Expression regulation and function of PD-1 and PD-L1 in T lymphoma cells

PD-1和PD-L1在T淋巴瘤细胞中的表达调控及功能

期刊:Cellular Immunology

影响因子:2.9

doi:10.1016/j.cellimm.2021.104397

Liu, Maria Y; Klement, John D; Langan, Candace J; van Riggelen, Jan; Liu, Kebin

SUV39H1 regulates human colon carcinoma apoptosis and cell cycle to promote tumor growth

SUV39H1通过调控人结肠癌细胞凋亡和细胞周期促进肿瘤生长

期刊:Cancer Letters

影响因子:10.1

doi:10.1016/j.canlet.2020.02.004

Lu, Chunwan; Klement, John D; Yang, Dafeng; Albers, Thomas; Lebedyeva, Iryna O; Waller, Jennifer L; Liu, Kebin

Osteopontin: A Key Regulator of Tumor Progression and Immunomodulation

骨桥蛋白：肿瘤进展和免疫调节的关键调控因子

期刊:Cancers

影响因子:4.4

doi:10.3390/cancers12113379

Moorman, Hannah R; Poschel, Dakota; Klement, John D; Lu, Chunwan; Redd, Priscilla S; Liu, Kebin

Loss of Fas Expression and Function Is Coupled with Colon Cancer Resistance to Immune Checkpoint Inhibitor Immunotherapy

Fas表达和功能的丧失与结肠癌对免疫检查点抑制剂免疫疗法的耐药性相关

期刊:Molecular Cancer Research

影响因子:4.7

doi:10.1158/1541-7786.MCR-18-0455

Xiao, Wei; Ibrahim, Mohammed L; Redd, Priscilla S; Klement, John D; Lu, Chunwan; Yang, Dafeng; Savage, Natasha M; Liu, Kebin

H3K4me3 mediates the NF-κB p50 homodimer binding to the pdcd1 promoter to activate PD-1 transcription in T cells

H3K4me3介导NF-κB p50同源二聚体与pdcd1启动子的结合，从而激活T细胞中的PD-1转录。

期刊:Oncoimmunology

影响因子:6.3

doi:10.1080/2162402X.2018.1483302

Redd, Priscilla S; Lu, Chunwan; Klement, John D; Ibrahim, Mohammed L; Zhou, Gang; Kumai, Takumi; Celis, Esteban; Liu, Kebin

IFNAR1 Controls Autocrine Type I IFN Regulation of PD-L1 Expression in Myeloid-Derived Suppressor Cells

IFNAR1 控制髓系来源抑制细胞中 I 型干扰素自分泌调节 PD-L1 表达

期刊:Journal of Immunology

影响因子:3.4

doi:10.4049/jimmunol.1800129

Xiao, Wei; Klement, John D; Lu, Chunwan; Ibrahim, Mohammed L; Liu, Kebin

Distinct and cooperative roles of host and tumor Osteopontin in colorectal cancer liver metastasis

宿主和肿瘤骨桥蛋白在结直肠癌肝转移中的独特和协作作用

STAT5 Activation Enhances Adoptive Therapy Combined with Peptide Vaccination by Preventing PD-1 Inhibition.

STAT5 激活通过阻止 PD-1 抑制来增强过继疗法与肽疫苗联合应用的效果

Osteopontin Blockade Immunotherapy Increases Cytotoxic T Lymphocyte Lytic Activity and Suppresses Colon Tumor Progression

骨桥蛋白阻断免疫疗法可增强细胞毒性T淋巴细胞的溶解活性并抑制结肠肿瘤进展

MS4A1 expression and function in T cells in the colorectal cancer tumor microenvironment

MS4A1在结直肠癌肿瘤微环境中T细胞中的表达和功能

Expression regulation and function of PD-1 and PD-L1 in T lymphoma cells

PD-1和PD-L1在T淋巴瘤细胞中的表达调控及功能

SUV39H1 regulates human colon carcinoma apoptosis and cell cycle to promote tumor growth

SUV39H1通过调控人结肠癌细胞凋亡和细胞周期促进肿瘤生长

Osteopontin: A Key Regulator of Tumor Progression and Immunomodulation

骨桥蛋白：肿瘤进展和免疫调节的关键调控因子

Loss of Fas Expression and Function Is Coupled with Colon Cancer Resistance to Immune Checkpoint Inhibitor Immunotherapy

Fas表达和功能的丧失与结肠癌对免疫检查点抑制剂免疫疗法的耐药性相关

H3K4me3 mediates the NF-κB p50 homodimer binding to the pdcd1 promoter to activate PD-1 transcription in T cells

H3K4me3介导NF-κB p50同源二聚体与pdcd1启动子的结合，从而激活T细胞中的PD-1转录。

IFNAR1 Controls Autocrine Type I IFN Regulation of PD-L1 Expression in Myeloid-Derived Suppressor Cells

IFNAR1 控制髓系来源抑制细胞中 I 型干扰素自分泌调节 PD-L1 表达