日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hematopoietic stem cell-derived adipocytes suppress leptin production, and attenuate ovariectomy-induced inhibition of physical activity and insulin sensitivity in female mice

造血干细胞来源的脂肪细胞抑制瘦素的产生,并减轻卵巢切除术引起的雌性小鼠运动能力下降和胰岛素敏感性降低。

Libby, Andrew E; Sullivan, Timothy M; Maltzahn, Joanne K; Jackman, Matthew R; Gavin, Kathleen M; MacLean, Paul S; Kohrt, Wendy M; Majka, Susan M; Klemm, Dwight J

Ablation of hematopoietic stem cell derived adipocytes reduces tumor burden in syngeneic mouse models of high-grade serous carcinoma

清除造血干细胞来源的脂肪细胞可降低同基因小鼠高级别浆液性癌模型中的肿瘤负荷

Woodruff, Elizabeth R; Bailey, Courtney A; To, Francis; Manda, Vyshnavi; Maltzahn, Joanne K; Sullivan, Timothy M; Boorgula, Meher P; Recouvreux, Maria Sol; Vianzon, Ruby; Conrad, Bogi; Gavin, Kathleen M; Jordan, Kimberly R; Klemm, Dwight J; Orsulic, Sandra; Bitler, Benjamin G; Watson, Zachary L

Adipogenic differentiation of hematopoietic lineage cells isolated from adipose tissue of humans

从人体脂肪组织中分离的造血谱系细胞的脂肪生成分化

Gavin, Kathleen M; Conrad, Bogdan; Sullivan, Timothy; Vianzon, Ruby; Acosta, Alistaire S; Kohrt, Wendy M; Klemm, Dwight J

Hematopoietic Stem Cell-Derived Adipocytes Modulate Adipose Tissue Cellularity, Leptin Production and Insulin Responsiveness in Female Mice

造血干细胞衍生的脂肪细胞调节雌性小鼠的脂肪组织细胞密度、瘦素生成和胰岛素反应性

Gavin, Kathleen M; Sullivan, Timothy M; Maltzahn, Joanne K; Jackman, Matthew R; Libby, Andrew E; MacLean, Paul S; Kohrt, Wendy M; Majka, Susan M; Klemm, Dwight J

Metabolite G-Protein Coupled Receptors in Cardio-Metabolic Diseases

代谢物G蛋白偶联受体在心血管代谢疾病中的作用

Strassheim, Derek; Sullivan, Timothy; Irwin, David C; Gerasimovskaya, Evgenia; Lahm, Tim; Klemm, Dwight J; Dempsey, Edward C; Stenmark, Kurt R; Karoor, Vijaya

Hematopoietic stem cells produce intermediate lineage adipocyte progenitors that simultaneously express both myeloid and mesenchymal lineage markers in adipose tissue

造血干细胞产生中间谱系脂肪细胞祖细胞,这些祖细胞在脂肪组织中同时表达髓系和间充质谱系标志物。

Gavin, Kathleen M; Sullivan, Timothy M; Maltzahn, Joanne K; Rahkola, Jeremy T; Acosta, Alistair S; Kohrt, Wendy M; Majka, Susan M; Klemm, Dwight J

CREB depletion in smooth muscle cells promotes medial thickening, adventitial fibrosis and elicits pulmonary hypertension

平滑肌细胞中 CREB 的缺失会促进血管中层增厚、外膜纤维化,并引发肺动脉高压。

Garat, Chrystelle V; Majka, Susan M; Sullivan, Timothy M; Crossno, Joseph T Jr; Reusch, Jane E B; Klemm, Dwight J

Inactivation of Tsc2 in Abcg2 lineage-derived cells drives the appearance of polycystic lesions and fibrosis in the adult kidney.

Abcg2 谱系衍生细胞中 Tsc2 的失活导致成年肾脏出现多囊性病变和纤维化

Gewin Leslie S, Summers Megan E, Harral Julie W, Gaskill Christa F, Khodo Stellor Nlandu, Neelisetty Surekha, Sullivan Timothy M, Hopp Katharina, Reese J Jeffrey, Klemm Dwight J, Kon Valentina, Ess Kevin C, Shi Wei, Majka Susan M

Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction

成人肺间充质祖细胞谱系分化紊乱会促进微血管功能障碍

Gaskill, Christa F; Carrier, Erica J; Kropski, Jonathan A; Bloodworth, Nathaniel C; Menon, Swapna; Foronjy, Robert F; Taketo, M Mark; Hong, Charles C; Austin, Eric D; West, James D; Means, Anna L; Loyd, James E; Merryman, W David; Hemnes, Anna R; De Langhe, Stijn; Blackwell, Timothy S; Klemm, Dwight J; Majka, Susan M

Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche

白血病干细胞通过代谢适应脂肪组织微环境来逃避化疗

Ye, Haobin; Adane, Biniam; Khan, Nabilah; Sullivan, Timothy; Minhajuddin, Mohammad; Gasparetto, Maura; Stevens, Brett; Pei, Shanshan; Balys, Marlene; Ashton, John M; Klemm, Dwight J; Woolthuis, Carolien M; Stranahan, Alec W; Park, Christopher Y; Jordan, Craig T