日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The E3-ome gene-centric compendium reveals the human E3 ligase landscape.

以 E3 连接酶组为中心的基因汇编揭示了人类 E3 连接酶的全貌。

Chua Ngee Kiat, González-Robles Tania J, Reddington Cameron J, Dudley-Fraser Jane, Birkinshaw Richard W, Han Jiru, Solano Ashleigh, Wong Soon Wei, Kochańczyk Tomasz, Peter Joshua J, Nakasone Mark A, Aust Florian, Munro Jacob, Tong Yeh Huei, Iskander Julie, Abeysekera Waruni, Garnham Alex, Huckstep Hannah, Ritchie Matthew E, Wertz Ingrid, Hymowitz Sarah, Kumar Sharad, Conaway Ron C, Privé Gilbert G, Bullock Alex N, Babon Jeffrey J, Klevit Rachel E, Lorenz Sonja, Ciulli Alessio, Fischer Eric S, Thomä Nicolas H, Nowak Radosław P, Schulman Brenda A, Rapé Michael, Rittinger Katrin, Pagan Julia K, Bahlo Melanie, Mackay Joel P, Mace Peter D, Lima Christopher D, Hay Ronald T, Komander David, Lechtenberg Bernhard C, Joazeiro Claudio A P, Pagano Michele, Hofmann Kay, Feltham Rebecca

Correction: Toggle switch residues control allosteric transitions in bacterial adhesins by participating in a concerted repacking of the protein core

更正:切换开关残基通过参与蛋白质核心的协同重组来控制细菌粘附素的变构转变。

Kisiela, Dagmara I; Magala, Pearl; Interlandi, Gianluca; Carlucci, Laura A; Ramos, Angelo; Tchesnokova, Veronika; Basanta, Benjamin; Yarov-Yarovoy, Vladimir; Avagyan, Hovhannes; Hovhannisyan, Anahit; Thomas, Wendy E; Stenkamp, Ronald E; Klevit, Rachel E; Sokurenko, Evgeni V

Small heat shock protein HSPB5 uses disorder to bind zinc with high affinity

小热休克蛋白HSPB5利用其无序结构以高亲和力结合锌。

Janowska, Maria K; Racigh, Vanesa; Woods, Christoper N; Fornasari, María Silvina; Klevit, Rachel E

Function within Disorder: Small heat shock proteins use different functional regions to chaperone tau aggregation

紊乱中的功能:小热休克蛋白利用不同的功能区域来分子伴侣介导tau蛋白聚集

Cervantes, Mia; Janowska, Maria K; Tuttle, Lisa M; Nath, Abhinav; Klevit, Rachel E

Antibodies disrupt bacterial adhesion by ligand mimicry and allosteric interference

抗体通过配体模拟和变构干扰来破坏细菌黏附。

Hvorecny, Kelli L; Interlandi, Gianluca; Veth, Tim S; Aprikian, Pavel; Manchenko, Anna; Tchesnokova, Veronika L; Dickinson, Miles S; Quispe, Joel D; Riley, Nicholas M; Klevit, Rachel E; Magala, Pearl; Sokurenko, Evgeni V; Kollman, Justin M

Activation mechanism of small heat shock protein HSPB5 revealed by disease-associated mutants

疾病相关突变体揭示的小热休克蛋白HSPB5的激活机制

Woods, Christopher N; Janowska, Maria K; Ulmer, Lindsey D; Kaur Sidhu, Jasleen; Stone, Natalie L; James, Ellie I; Guttman, Miklos; Bush, Matthew F; Klevit, Rachel E

Force transmission through the inner kinetochore is enhanced by centromeric DNA sequences

着丝粒DNA序列增强了通过内动粒的力传递。

Elise Miedlar ,Grace E Hamilton ,Samuel R Witus ,Sara J Gonske ,Michael Riffle ,Alex Zelter ,Rachel E Klevit ,Charles L Asbury ,Yoana N Dimitrova ,Trisha N Davis

Mapping Hydrogen Migration Thresholds for Site-Specific HDX-MS

利用氢氘交换质谱法绘制位点特异性氢迁移阈值图谱

Mundorff, Charles C; Hadley, Sarah; Tuttle, Lisa M; Shi, Yuqi; McAlister, Graeme C; Viner, Rosa; Klevit, Rachel E; Guttman, Miklos

Rigorous Analysis of Multimodal HDX-MS Spectra

对多模态HDX-MS光谱进行严格分析

Tuttle, Lisa M; James, Ellie I; Georgescauld, Florian; Wales, Thomas E; Weis, David D; Engen, John R; Nath, Abhinav; Klevit, Rachel E; Guttman, Miklos

Disorder with consequence: Phosphorylation sites in HSPB5 yield distinct structural outcomes

紊乱及其后果:HSPB5 中的磷酸化位点导致不同的结构结果

Stone, Natalie L; Janowska, Maria K; Narisawa, Lucas; Tuttle, Lisa M; Ulmer, Lindsey D; Guttman, Miklos; Bush, Matthew F; Klevit, Rachel E