日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Foundational Shift in Models for Enzyme Function

酶功能模型的基础性转变

Klinman, Judith P; Miller, Susan M; Richards, Nigel G J

Dynamically Interacting Protein Networks Provide a Mechanism to Overcome the Enormous Intrinsic Barrier to Orotidine 5'-Monophosphate Decarboxylation

动态相互作用的蛋白质网络提供了一种克服乳清酸5'-单磷酸脱羧反应巨大内在障碍的机制

Dubey, Pankaj; Somani, Anish; Lin, Jessica; Iavarone, Anthony T; Klinman, Judith P

Identification of Scaffold Specific Energy Transfer Networks in the Enthalpic Activation of Orotidine 5'-Monophosphate Decarboxylase

鉴定乳清酸5'-单磷酸脱羧酶焓活化过程中的骨架特异性能量转移网络

Dubey, Pankaj; Somani, Anish; Lin, Jessica; Iavarone, Anthony T; Klinman, Judith P

Correlated Motion-Based Residue Network Analysis Reveals the Distal Thermal Activation in Soybean Lipoxygenase

基于相关运动的残基网络分析揭示大豆脂氧合酶的远端热激活

Jiang, Yaoyukun; Cordova, Jaden P; Klinman, Judith P

Temporal Resolution of Activity-Related Solvation Dynamics in the TIM Barrel Enzyme Murine Adenosine Deaminase

小鼠腺苷脱氨酶TIM桶状酶活性相关溶剂化动力学的时间分辨率

Gao, Shuaihua; Wu, Xin Ting; Zhang, Wenju; Richardson, Tyre; Barrow, Samuel L; Thompson-Kucera, Christian A; Iavarone, Anthony T; Klinman, Judith P

Hydrogen-Deuterium Exchange Mass Spectrometry Identifies Local and Long-Distance Interactions within the Multicomponent Radical SAM Enzyme, PqqE

氢氘交换质谱法鉴定多组分自由基SAM酶PqqE内部的局部和长程相互作用

Zhu, Wen; Iavarone, Anthony T; Klinman, Judith P

Dynamical activation of function in metalloenzymes

金属酶功能的动态激活

Klinman, Judith P

Identification of Thermal Conduits That Link the Protein-Water Interface to the Active Site Loop and Catalytic Base in Enolase

烯醇化酶中连接蛋白质-水界面与活性位点环和催化碱基的热通道的鉴定

Thompson, Emily J; Paul, Adhayana; Iavarone, Anthony T; Klinman, Judith P

Structural Properties and Catalytic Implications of the SPASM Domain Iron-Sulfur Clusters in Methylorubrum extorquens PqqE

甲基红杆菌 PqqE 中 SPASM 结构域铁硫簇的结构特性及其催化意义

Zhu, Wen; Walker, Lindsey M; Tao, Lizhi; Iavarone, Anthony T; Wei, Xuetong; Britt, R David; Elliott, Sean J; Klinman, Judith P

Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments

关于氢氘交换质谱(HDX-MS)实验的执行、解释和报告的建议

Masson, Glenn R; Burke, John E; Ahn, Natalie G; Anand, Ganesh S; Borchers, Christoph; Brier, Sébastien; Bou-Assaf, George M; Engen, John R; Englander, S Walter; Faber, Johan; Garlish, Rachel; Griffin, Patrick R; Gross, Michael L; Guttman, Miklos; Hamuro, Yoshitomo; Heck, Albert J R; Houde, Damian; Iacob, Roxana E; Jørgensen, Thomas J D; Kaltashov, Igor A; Klinman, Judith P; Konermann, Lars; Man, Petr; Mayne, Leland; Pascal, Bruce D; Reichmann, Dana; Skehel, Mark; Snijder, Joost; Strutzenberg, Timothy S; Underbakke, Eric S; Wagner, Cornelia; Wales, Thomas E; Walters, Benjamin T; Weis, David D; Wilson, Derek J; Wintrode, Patrick L; Zhang, Zhongqi; Zheng, Jie; Schriemer, David C; Rand, Kasper D