日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Harnessing NK Cell Checkpoint-Modulating Immunotherapies

利用NK细胞检查点调节免疫疗法

Chauhan, Sachin Kumar Singh; Koehl, Ulrike; Kloess, Stephan

CAR-Expressing Natural Killer Cells for Cancer Retargeting

表达CAR的自然杀伤细胞用于癌症靶向治疗

Kloess, Stephan; Kretschmer, Anna; Stahl, Lilly; Fricke, Stephan; Koehl, Ulrike

Development of Automated Separation, Expansion, and Quality Control Protocols for Clinical-Scale Manufacturing of Primary Human NK Cells and Alpharetroviral Chimeric Antigen Receptor Engineering.

开发用于临床规模生产原代人NK细胞和α逆转录病毒嵌合抗原受体工程的自动化分离、扩增和质量控制方案

Oberschmidt Olaf, Morgan Michael, Huppert Volker, Kessler Joerg, Gardlowski Tanja, Matthies Nadine, Aleksandrova Krasimira, Arseniev Lubomir, Schambach Axel, Koehl Ulrike, Kloess Stephan

Triplebody Mediates Increased Anti-Leukemic Reactivity of IL-2 Activated Donor Natural Killer (NK) Cells and Impairs Viability of Their CD33-Expressing NK Subset

三体介导IL-2激活的供体自然杀伤(NK)细胞抗白血病反应性增强,并损害其表达CD33的NK细胞亚群的活力。

Kloess, Stephan; Ede Valverde da Silva, Alessa; Oberschmidt, Olaf; Gardlowski, Tanja; Matthies, Nadine; Vyas, Maulik; Arseniev, Lubomir; Heuser, Michael; Pogge von Strandmann, Elke; Köhl, Ulrike

Redirected Primary Human Chimeric Antigen Receptor Natural Killer Cells As an "Off-the-Shelf Immunotherapy" for Improvement in Cancer Treatment

重定向的人类嵌合抗原受体自然杀伤细胞作为一种“现成的免疫疗法”用于改善癌症治疗

Oberschmidt, Olaf; Kloess, Stephan; Koehl, Ulrike

Advantages and applications of CAR-expressing natural killer cells

表达CAR的自然杀伤细胞的优势和应用

Glienke, Wolfgang; Esser, Ruth; Priesner, Christoph; Suerth, Julia D; Schambach, Axel; Wels, Winfried S; Grez, Manuel; Kloess, Stephan; Arseniev, Lubomir; Koehl, Ulrike

Clinical grade purification and expansion of NK cell products for an optimized manufacturing protocol

临床级NK细胞产品的纯化和扩增,以优化生产方案

Koehl, Ulrike; Brehm, Claudia; Huenecke, Sabine; Zimmermann, Stefanie-Yvonne; Kloess, Stephan; Bremm, Melanie; Ullrich, Evelyn; Soerensen, Jan; Quaiser, Andrea; Erben, Stephanie; Wunram, Claudia; Gardlowski, Tanja; Auth, Eileen; Tonn, Torsten; Seidl, Christian; Meyer-Monard, Sandrine; Stern, Martin; Passweg, Jakob; Klingebiel, Thomas; Bader, Peter; Schwabe, Dirk; Esser, Ruth

NK cells engineered to express a GD2 -specific antigen receptor display built-in ADCC-like activity against tumour cells of neuroectodermal origin

经基因工程改造表达GD2特异性抗原受体的NK细胞,对神经外胚层来源的肿瘤细胞表现出内在的ADCC样活性。

Esser, Ruth; Müller, Tina; Stefes, Dörthe; Kloess, Stephan; Seidel, Diana; Gillies, Stephen D; Aperlo-Iffland, Christel; Huston, James S; Uherek, Christoph; Schönfeld, Kurt; Tonn, Torsten; Huebener, Nicole; Lode, Holger N; Koehl, Ulrike; Wels, Winfried S