日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A Dynamic Stress Model Explains the Delayed Drug Effect in Artemisinin Treatment of Plasmodium falciparum

动态应激模型解释了青蒿素治疗恶性疟原虫的延迟药物效应

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00618-17
Cao, Pengxing; Klonis, Nectarios; Zaloumis, Sophie; Dogovski, Con; Xie, Stanley C; Saralamba, Sompob; White, Lisa J; Fowkes, Freya J I; Tilley, Leann; Simpson, Julie A; McCaw, James M
发表日期：2017
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Reversible host cell remodeling underpins deformability changes in malaria parasite sexual blood stages

可逆的宿主细胞重塑是疟原虫有性血液期变形能力变化的基础。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1520194113
Dearnley, Megan; Chu, Trang; Zhang, Yao; Looker, Oliver; Huang, Changjin; Klonis, Nectarios; Yeoman, Jeff; Kenny, Shannon; Arora, Mohit; Osborne, James M; Chandramohanadas, Rajesh; Zhang, Sulin; Dixon, Matthew W A; Tilley, Leann
细胞生物学
发表日期：2016
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Comparison of the Exposure Time Dependence of the Activities of Synthetic Ozonide Antimalarials and Dihydroartemisinin against K13 Wild-Type and Mutant Plasmodium falciparum Strains

合成臭氧化物抗疟药和双氢青蒿素对K13野生型和突变型恶性疟原虫株活性的暴露时间依赖性比较

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00574-16
Yang, Tuo; Xie, Stanley C; Cao, Pengxing; Giannangelo, Carlo; McCaw, James; Creek, Darren J; Charman, Susan A; Klonis, Nectarios; Tilley, Leann
发表日期：2016
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Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisinins

血红蛋白降解是早期环状疟原虫对青蒿素敏感的根本原因。

期刊:Journal of Cell Science
影响因子:3.6
doi:10.1242/jcs.178830
Xie, Stanley C; Dogovski, Con; Hanssen, Eric; Chiu, Francis; Yang, Tuo; Crespo, Maria P; Stafford, Che; Batinovic, Steven; Teguh, Silvia; Charman, Susan; Klonis, Nectarios; Tilley, Leann
蛋白降解
发表日期：2016
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Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance

靶向恶性疟原虫的细胞应激反应以克服青蒿素耐药性

期刊:PLoS Biology
影响因子:7.2
doi:10.1371/journal.pbio.1002132
Dogovski, Con; Xie, Stanley C; Burgio, Gaetan; Bridgford, Jess; Mok, Sachel; McCaw, James M; Chotivanich, Kesinee; Kenny, Shannon; Gnädig, Nina; Straimer, Judith; Bozdech, Zbynek; Fidock, David A; Simpson, Julie A; Dondorp, Arjen M; Foote, Simon; Klonis, Nectarios; Tilley, Leann
细胞生物学
发表日期：2015
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Altered temporal response of malaria parasites determines differential sensitivity to artemisinin

疟原虫时间反应的改变决定了其对青蒿素的敏感性差异

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1217452110
Klonis, Nectarios; Xie, Stanley C; McCaw, James M; Crespo-Ortiz, Maria P; Zaloumis, Sophie G; Simpson, Julie A; Tilley, Leann
发表日期：2013
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Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion

青蒿素对抗恶性疟原虫的活性需要血红蛋白的吸收和消化。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1104063108
Klonis, Nectarios; Crespo-Ortiz, Maria P; Bottova, Iveta; Abu-Bakar, Nurhidanatasha; Kenny, Shannon; Rosenthal, Philip J; Tilley, Leann
发表日期：2011
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Cryo transmission X-ray imaging of the malaria parasite, P. falciparum

利用低温透射X射线成像技术对疟原虫（恶性疟原虫）进行成像

期刊:Journal of Structural Biology
影响因子:2.7
doi:10.1016/j.jsb.2010.08.013
Hanssen, Eric; Knoechel, Christian; Klonis, Nectarios; Abu-Bakar, Nurhidanatasha; Deed, Samantha; LeGros, Mark; Larabell, Carolyn; Tilley, Leann
发表日期：2011
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Evaluation of pH during cytostomal endocytosis and vacuolar catabolism of haemoglobin in Plasmodium falciparum

恶性疟原虫胞质内吞作用和血红蛋白液泡分解代谢过程中pH值的评估

期刊:Biochemical Journal
影响因子:4.3
doi:10.1042/BJ20070934
Klonis, Nectarios; Tan, Olivia; Jackson, Katherine; Goldberg, Daniel; Klemba, Michael; Tilley, Leann
代谢
发表日期：2007
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A cluster of ring stage-specific genes linked to a locus implicated in cytoadherence in Plasmodium falciparum codes for PEXEL-negative and PEXEL-positive proteins exported into the host cell

在恶性疟原虫中，一组与细胞黏附相关的环状体期特异性基因簇编码PEXEL阴性和PEXEL阳性蛋白，这些蛋白被输出到宿主细胞中。

期刊:Molecular Biology of the Cell
影响因子:2.7
doi:10.1091/mbc.e06-04-0291
Spielmann, Tobias; Hawthorne, Paula L; Dixon, Matthew W A; Hannemann, Mandy; Klotz, Kathleen; Kemp, David J; Klonis, Nectarios; Tilley, Leann; Trenholme, Katharine R; Gardiner, Donald L
细胞生物学
Adhesion/ECM
发表日期：2006
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