日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Decreased mitochondrial transcription factor A and mitochondrial DNA copy number promote cyclin-dependent kinase inhibitor 1A expression and reduce tumorigenic properties of colorectal cancer cells.

线粒体转录因子 A 和线粒体 DNA 拷贝数的减少促进细胞周期蛋白依赖性激酶抑制剂 1A 的表达,并降低结直肠癌细胞的致瘤性

Buchwaldt Jessika, Fritsch Tania, Hartmann Monika, Witzel Hagen Roland, Kloth Michael, Roth Wilfried, Tagscherer Katrin E, Hartmann Nils

A novel targeted NGS panel identifies numerous homologous recombination deficiency (HRD)-associated gene mutations in addition to known BRCA mutations

一种新型靶向NGS检测板除了能识别已知的BRCA突变外,还能识别出许多与同源重组缺陷(HRD)相关的基因突变。

Vogel, Anne; Haupts, Anna; Kloth, Michael; Roth, Wilfried; Hartmann, Nils

Cancer gene related characterization of patterns and point of recurrence after resection of colorectal liver metastases

结直肠癌肝转移切除术后复发模式及复发点的癌症基因相关特征

Lang, Hauke; Baumgart, Janine; Roth, Wilfried; Moehler, Markus; Kloth, Michael

Exome sequencing characterizes the somatic mutation spectrum of early serrated lesions in a patient with serrated polyposis syndrome (SPS)

外显子组测序表征了锯齿状息肉综合征(SPS)患者早期锯齿状病变的体细胞突变谱。

Horpaopan, Sukanya; Kirfel, Jutta; Peters, Sophia; Kloth, Michael; Hüneburg, Robert; Altmüller, Janine; Drichel, Dmitriy; Odenthal, Margarete; Kristiansen, Glen; Strassburg, Christian; Nattermann, Jacob; Hoffmann, Per; Nürnberg, Peter; Büttner, Reinhard; Thiele, Holger; Kahl, Philip; Spier, Isabel; Aretz, Stefan

Exome Sequencing Identifies Biallelic MSH3 Germline Mutations as a Recessive Subtype of Colorectal Adenomatous Polyposis.

外显子组测序发现双等位基因 MSH3 生殖系突变是结直肠腺瘤性息肉病的隐性亚型

Adam Ronja, Spier Isabel, Zhao Bixiao, Kloth Michael, Marquez Jonathan, Hinrichsen Inga, Kirfel Jutta, Tafazzoli Aylar, Horpaopan Sukanya, Uhlhaas Siegfried, Stienen Dietlinde, Friedrichs Nicolaus, Altmüller Janine, Laner Andreas, Holzapfel Stefanie, Peters Sophia, Kayser Katrin, Thiele Holger, Holinski-Feder Elke, Marra Giancarlo, Kristiansen Glen, Nöthen Markus M, Büttner Reinhard, Möslein Gabriela, Betz Regina C, Brieger Angela, Lifton Richard P, Aretz Stefan

Immune checkpoints programmed death 1 ligand 1 and cytotoxic T lymphocyte associated molecule 4 in gastric adenocarcinoma

胃腺癌中的免疫检查点:程序性死亡配体1和细胞毒性T淋巴细胞相关分子4

Schlößer, Hans A; Drebber, Uta; Kloth, Michael; Thelen, Martin; Rothschild, Sacha I; Haase, Simon; Garcia-Marquez, Maria; Wennhold, Kerstin; Berlth, Felix; Urbanski, Alexander; Alakus, Hakan; Schauss, Astrid; Shimabukuro-Vornhagen, Alexander; Theurich, Sebastian; Warnecke-Ebertz, Ute; Stippel, Dirk L; Zippelius, Alfred; Büttner, Reinhard; Hallek, Michael; Hölscher, Arnulf H; Zander, Thomas; Mönig, Stefan P; von Bergwelt-Baildon, Michael

Molecular and clinical evidence for an ARMC5 tumor syndrome: concurrent inactivating germline and somatic mutations are associated with both primary macronodular adrenal hyperplasia and meningioma

ARMC5肿瘤综合征的分子和临床证据:同时发生的失活种系突变和体细胞突变与原发性大结节性肾上腺增生和脑膜瘤均相关

Elbelt, Ulf; Trovato, Alessia; Kloth, Michael; Gentz, Enno; Finke, Reinhard; Spranger, Joachim; Galas, David; Weber, Susanne; Wolf, Cristina; König, Katharina; Arlt, Wiebke; Büttner, Reinhard; May, Patrick; Allolio, Bruno; Schneider, Jochen G

Changing histopathological diagnostics by genome-based tumor classification

基于基因组的肿瘤分类改变组织病理学诊断

Kloth, Michael; Buettner, Reinhard