日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Computational design of potent and selective binders of BAK and BAX.

利用计算机设计高效选择性 BAK 和 BAX 结合剂

Berger Stephanie, Lee Erinna F, Harris Tiffany J, Tran Sharon, Bera Asim K, Arguinchona Lauren, Kang Alex, Sankaran Banumathi, Kasapgil Sila, Miller Michelle S, Smyth Sean, Lutfi Mariam, Uren Rachel T, Kluck Ruth M, Colman Peter M, Fairlie Walter D, Czabotar Peter E, Baker David, Birkinshaw Richard W

A lipid signature of BAK-driven apoptotic pore formation

BAK驱动的细胞凋亡孔形成的脂质特征

Uren, Rachel T; Ritchie, Matthew E; Wong, Agnes W; Ludeman, Justin P; Uno, Etsuko; Narayana, Vinod K; De Souza, David P; Sviridov, Dmitri; Kluck, Ruth M

Avoiding adsorption of Bcl-2 proteins to plasticware is important for accurate quantitation

避免Bcl-2蛋白吸附到塑料器皿上对于准确定量至关重要。

Hockings, Colin; Iyer, Sweta; Uren, Rachel T; Kluck, Ruth M

MCMV-mediated inhibition of the pro-apoptotic Bak protein is required for optimal in vivo replication

MCMV介导的促凋亡蛋白Bak的抑制是体内最佳复制所必需的。

Fleming, Peter; Kvansakul, Marc; Voigt, Valentina; Kile, Benjamin T; Kluck, Ruth M; Huang, David C S; Degli-Esposti, Mariapia A; Andoniou, Christopher E

Assembly of the Bak apoptotic pore: a critical role for the Bak protein α6 helix in the multimerization of homodimers during apoptosis.

Bak凋亡孔的组装:Bak蛋白α6螺旋在细胞凋亡过程中同源二聚体多聚化中的关键作用

Ma Stephen, Hockings Colin, Anwari Khatira, Kratina Tobias, Fennell Stephanie, Lazarou Michael, Ryan Michael T, Kluck Ruth M, Dewson Grant

Inhibition of Bak activation by VDAC2 is dependent on the Bak transmembrane anchor

VDAC2对Bak活化的抑制作用依赖于Bak的跨膜锚定结构。

Lazarou, Michael; Stojanovski, Diana; Frazier, Ann E; Kotevski, Aneta; Dewson, Grant; Craigen, William J; Kluck, Ruth M; Vaux, David L; Ryan, Michael T

Mechanisms by which Bak and Bax permeabilise mitochondria during apoptosis

Bak和Bax在细胞凋亡过程中使线粒体通透性的机制

Dewson, Grant; Kluck, Ruth M

Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak

线粒体通透性改变依赖于BH3配体与多种促生存Bcl-2家族成员的结合,而非Bak蛋白。

Uren, Rachel T; Dewson, Grant; Chen, Lin; Coyne, Stephanie C; Huang, David C S; Adams, Jerry M; Kluck, Ruth M