日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Evolving epigenomics of immune cells at single-nucleus resolution in children en route to type 1 diabetes

儿童发展为 1 型糖尿病过程中免疫细胞单核分辨率的表观基因组演变

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69923-x
Pastinen, Tomi; Grundberg, Elin; Bradley, Todd; Honkanen, Jarno; Cheung, Warren A; Vuorela, Arja; Johnston, Jeffrey J; Yoo, Byunggil; Khanal, Santosh; McLennan, Rebecca; Ilonen, Jorma; Vaarala, Outi; Krischer, Jeffrey P; Knip, Mikael
表观遗传
代谢
糖尿病
细胞生物学
免疫/内分泌
发表日期：2026
文献求助 收藏

Autoantibody Response Toward Chromatin in Patients With Juvenile Idiopathic Arthritis

幼年特发性关节炎患者针对染色质的自身抗体反应

期刊:Arthritis & Rheumatology
影响因子:10.9
doi:10.1002/art.43315
Pitkänen, Viola; Remes-Pakarinen, Terhi; Vähäsalo, Paula; Möttönen, Milja; Grönlund, Minna-Maija; Arvonen, Miika; Knip, Mikael; Veijola, Riitta; Toppari, Jorma; Ilonen, Jorma; Lempainen, Johanna; Schroderus, Anna-Mari; Kröger, Liisa; Kinnunen, Tuure
关节炎
免疫/内分泌
发表日期：2026
文献求助 收藏

Dietary intake of vitamins A, B, C, D and E and risk of islet autoimmunity and type 1 diabetes in genetically at-risk children: a prospective study from the DIPP birth cohort

维生素A、B、C、D和E的膳食摄入量与遗传高危儿童胰岛自身免疫和1型糖尿病风险的关系：一项来自DIPP出生队列的前瞻性研究

期刊:Diabetologia
影响因子:10.2
doi:10.1007/s00125-025-06635-9
Mattila, Markus; Haario, Peppi; Hakola, Leena; Takkinen, Hanna-Mari; Peltonen, Essi J; Korhonen, Tuuli E; Ahonen, Suvi; Ilonen, Jorma; Toppari, Jorma; Knip, Mikael; Veijola, Riitta; Niinistö, Sari; Virtanen, Suvi M
代谢
糖尿病
免疫/内分泌
发表日期：2026
文献求助 收藏

Early-life immunological and microbial differences between East African and North European children

东非儿童和北欧儿童早期免疫和微生物差异

期刊:
影响因子:
doi:10.1038/s43856-026-01482-0
Nurminen, Noora; Fan, Yue-Mei; Kortekangas, Emma; Lin, Jake; Hallamaa, Lotta; Maleta, Kenneth; Lehto, Kirsi-Maarit; Laitinen, Olli H; Sinkkonen, Aki; Lempainen, Johanna; Toppari, Jorma; Veijola, Riitta; Kurppa, Kalle; Knip, Mikael; Ashorn, Ulla; Oikarinen, Sami; Ashorn, Per; Hyöty, Heikki
微生物学
免疫/内分泌
发表日期：2026
文献求助 收藏

Microbiome-derived bile acid signatures in early life and their association with islet autoimmunity.

生命早期微生物组来源的胆汁酸特征及其与胰岛自身免疫的关系。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-66619-6
Lamichhane Santosh, Dickens Alex M, Buchacher Tanja, Lou Tianai, Charron-Lamoureux Vincent, Kattelus Roosa, Karmacharya Pragya, da Silva Lucas Pinto, Kråkström Matilda, Rasool Omid, Sen Partho, Walker Corinn, Patan Abubaker, Gentry Emily C, Zuffa Simone, Arzoomand Aron, Lakshmikanth Tadepally, Mikeš Jaromir, Mebrahtu Aman, Vatanen Tommi, Raffatellu Manuela, Zengler Karsten, Hyötyläinen Tuulia, Xavier Ramnik J, Brodin Petter, Lahesmaa Riitta, Dorrestein Pieter C, Knip Mikael, Orešič Matej
微生物学
免疫/内分泌
发表日期：2025
文献求助 收藏

Single-cell RNA-seq analysis of longitudinal CD4(+) T cell samples reveals cell-type-specific changes during early stages of type 1 diabetes

对纵向 CD4(+) T 细胞样本进行单细胞 RNA 测序分析，揭示了 1 型糖尿病早期阶段细胞类型特异性变化

期刊:Genome Medicine
影响因子:11.2
doi:10.1186/s13073-025-01574-x
Biradar, Rahul; Kalim, Ubaid Ullah; Lönnberg, Tapio; Junttila, Sini; Suomi, Tomi; Norman, Sebastián Zúñiga; Starskaia, Inna; Paulin, Niklas; Mikkola, Lea; Vaarala, Outi; Rasool, Omid; Knip, Mikael; Elo, Laura L; Lahesmaa, Riitta
T细胞
代谢
糖尿病
细胞生物学
CD4
单细胞
发表日期：2025
文献求助 收藏

Targeted serum proteomics of longitudinal samples from newly diagnosed youth with type 1 diabetes affirms markers of disease

对新诊断的1型糖尿病青少年纵向样本进行靶向血清蛋白质组学分析，证实了疾病标志物的存在。

期刊:Diabetologia
影响因子:10.2
doi:10.1007/s00125-025-06394-7
Moulder, Robert; Hirvonen, M Karoliina; Välikangas, Tommi; Suomi, Tomi; Overbergh, Lut; Peakman, Mark; Brunak, Søren; Mathieu, Chantal; Knip, Mikael; Elo, Laura L; Lahesmaa, Riitta
糖尿病
代谢
发表日期：2025
文献求助 收藏

Islet autoimmunity and progression to type 1 diabetes in the Finnish DIPP study: comparison between genetically susceptible children with and without an affected first-degree relative

芬兰DIPP研究中胰岛自身免疫与1型糖尿病进展：有无一级亲属患病的遗传易感儿童的比较

期刊:Diabetologia
影响因子:10.2
doi:10.1007/s00125-025-06573-6
Kuusela, Salla; Koskenniemi, Jaakko J; Valtanen, Toni; Pokka, Tytti; Härkönen, Taina; Ilonen, Jorma; Lempainen, Johanna; Kyrönniemi, Anni; Toppari, Jorma; Knip, Mikael; Keskinen, Päivi; Veijola, Riitta
代谢
糖尿病
免疫/内分泌
发表日期：2025
文献求助 收藏

Associations between dietary fibers and gut microbiome composition in the EDIA longitudinal infant cohort

EDIA纵向婴儿队列研究中膳食纤维与肠道微生物群组成之间的关联

期刊:American Journal of Clinical Nutrition
影响因子:6.9
doi:10.1016/j.ajcnut.2024.11.011
Lalli, Marianne K; Salo, Tuuli Ei; Hakola, Leena; Knip, Mikael; Virtanen, Suvi M; Vatanen, Tommi
微生物学
发表日期：2025
文献求助 收藏

Increased Risk of Type 1 Diabetes in Boys Under the Age of 5 Years During COVID-19 Lockdowns in Finland, Sweden and Stanford, CA, USA-An Observational Multicenter Study

芬兰、瑞典和美国加州斯坦福市 COVID-19 封锁期间 5 岁以下男孩患 1 型糖尿病风险增加——一项观察性多中心研究

期刊:Diabetes-Metabolism Research and Reviews
影响因子:6
doi:10.1002/dmrr.70084
Tall, Susanna; Prahalad, Priya; Adiels, Martin; Rosengren, Annika; Virtanen, Suvi M; Maahs, David M; Knip, Mikael
糖尿病
代谢
发表日期：2025
文献求助 收藏