日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Divergent response to radio-immunotherapy is defined by intrinsic features of the tumor microenvironment

对放射免疫疗法的不同反应是由肿瘤微环境的内在特征决定的。

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2024-010405
Gadwa, Jacob; Yu, Justin; Piper, Miles; Knitz, Michael W; Darragh, Laurel B; Olimpo, Nicholas; Corbo, Sophia; Beynor, Jessica I; Neupert, Brooke; Nguyen, Alexander T; Hodgson, Chloe; Nguyen, Diemmy; Abdelazeem, Khalid Nm; Saviola, Anthony; Pousse, Laurene; Bransi, Ali; Pincha, Mudita; Klein, Christian; Amann, Maria; Karam, Sana D
肿瘤
肿瘤微环境
肿瘤免疫
免疫/内分泌
发表日期：2025
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Intraoperative CT evaluation of repositioning accuracy in zygomaticomaxillary complex fractures: 1-point versus multiple-point fixation

术中CT评估颧颌复合体骨折复位精度：单点固定与多点固定的比较

期刊:Head & Face Medicine
影响因子:2.6
doi:10.1186/s13005-025-00558-x
Sakkas, Andreas; Schulze, Johannes; Scheurer, Mario; Rana, Majeed; Kasper, Robin; Ebeling, Marcel; Schramm, Alexander; Wilde, Frank; Knitz, Marc
骨折
发表日期：2025
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Author Correction: Elective nodal irradiation mitigates local and systemic immunity generated by combination radiation and immunotherapy in head and neck tumors

作者更正：选择性淋巴结照射可减轻头颈部肿瘤中联合放疗和免疫疗法产生的局部和全身免疫反应。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-024-52861-x
Darragh, Laurel B; Gadwa, Jacob; Pham, Tiffany T; Van Court, Benjamin; Neupert, Brooke; Olimpo, Nicholas A; Nguyen, Khoa; Nguyen, Diemmy; Knitz, Michael W; Hoen, Maureen; Corbo, Sophia; Joshi, Molishree; Zhuang, Yonghua; Amann, Maria; Wang, Xiao-Jing; Dow, Steven; Kedl, Ross M; Samedi, Von; Boss, Mary-Keara; Karam, Sana D
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2024
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Sensory nerve release of CGRP increases tumor growth in HNSCC by suppressing TILs

感觉神经释放的CGRP通过抑制TILs促进头颈部鳞状细胞癌的肿瘤生长。

期刊:Med
影响因子:12.8
doi:10.1016/j.medj.2024.02.002
Laurel B Darragh ，Alexander Nguyen ，Tiffany T Pham ，Shaquia Idlett-Ali ，Michael W Knitz ，Jacob Gadwa ，Sanjana Bukkapatnam ，Sophia Corbo ，Nicholas A Olimpo ，Diemmy Nguyen ，Benjamin Van Court ，Brooke Neupert ，Justin Yu ，Richard B Ross ，Michaele Corbisiero ，Khalid N M Abdelazeem ，Sean P Maroney ，David C Galindo ，Laith Mukdad ，Anthony Saviola ，Molishree Joshi ，Ruth White ，Yazeed Alhiyari ，Von Samedi ，Adrie Van Bokhoven ，Maie St John ，Sana D Karam
神经科学
肿瘤
T细胞
GRP
肿瘤免疫
发表日期：2024
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PPARα Agonism Enhances Immune Response to Radiotherapy While Dietary Oleic Acid Results in Counteraction

PPARα激动剂可增强放射疗法的免疫反应，而膳食油酸则会产生拮抗作用。

期刊:Clinical Cancer Research
影响因子:10
doi:10.1158/1078-0432.CCR-23-3433
Richard Blake Ross ，Jacob Gadwa ，Justin Yu ，Laurel B Darragh ，Michael W Knitz ，Diemmy Nguyen ，Nicholas A Olimpo ，Khalid N M Abdelazeem ，Alexander Nguyen ，Sophia Corbo ，Benjamin Van Court ，Jessica Beynor ，Brooke Neupert ，Anthony J Saviola ，Angelo D'Alessandro ，Sana D Karam
免疫/内分泌
发表日期：2024
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IL7 in combination with radiotherapy stimulates a memory T-cell response to improve outcomes in HNSCC models

IL7 与放射疗法联合使用可刺激记忆 T 细胞反应，从而改善 HNSCC 模型的预后

期刊:Cancer Immunology Immunotherapy
影响因子:8.1
doi:10.1007/s00262-024-03664-y
Justin Yu, Jacob Gadwa, Richard B Ross, Michael Knitz, Laurel B Darragh, Khalid N M Abdelazeem, Jessica Beynor, Brooke Neupert, Alexander Nguyen, Diemmy Nguyen, Nicholas Olimpo, Sophia Corbo, Benjamin Van Court, Angelo D'Alessandro, Anthony Saviola, Sana D Karam
细胞生物学
T细胞
发表日期：2024
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IL15/IL15Rα complex induces an anti-tumor immune response following radiation therapy only in the absence of Tregs and fails to induce expansion of progenitor TCF1+ CD8 T cells

IL15/IL15Rα复合物仅在缺乏调节性T细胞（Tregs）的情况下才能在放射治疗后诱导抗肿瘤免疫反应，并且不能诱导祖细胞TCF1+ CD8 T细胞的扩增。

期刊:
影响因子:
doi:10.1101/2024.09.18.613691
Piper, Miles; Gadwa, Jacob; Hodgson, Chloe; Knitz, Michael; Yee, Elliott; Zhu, Yuwen; Larson, Keira Y; Klein, Christian; Amann, Maria; Saviola, Anthony; Karam, Sana D
肿瘤
T细胞
肿瘤免疫
CD8
Treg
T细胞
细胞生物学
免疫/内分泌
发表日期：2024
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Simultaneous targeting of PD-1 and IL-2Rβγ with radiation therapy inhibits pancreatic cancer growth and metastasis

放射疗法同时靶向PD-1和IL-2Rβγ可抑制胰腺癌的生长和转移。

期刊:Cancer Cell
影响因子:48.8
doi:10.1016/j.ccell.2023.04.001
Miles Piper ，Maureen Hoen ，Laurel B Darragh ，Michael W Knitz ，Diemmy Nguyen ，Jacob Gadwa ，Greta Durini ，Idil Karakoc ，Abby Grier ，Brooke Neupert ，Benjamin Van Court ，Khalid N M Abdelazeem ，Justin Yu ，Nicholas A Olimpo ，Sophia Corbo ，Richard Blake Ross ，Tiffany T Pham ，Molishree Joshi ，Ross M Kedl ，Anthony J Saviola ，Maria Amann ，Pablo Umaña ，Laura Codarri Deak ，Christian Klein ，Angelo D'Alessandro ，Sana D Karam
胰腺癌
IL-2
肿瘤
肿瘤免疫
PD-1
发表日期：2023
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Selective targeting of IL2Rβγ combined with radiotherapy triggers CD8- and NK-mediated immunity, abrogating metastasis in HNSCC

选择性靶向IL2Rβγ联合放射疗法可激活CD8和NK细胞介导的免疫反应，从而抑制头颈部鳞状细胞癌的转移。

期刊:Cell Reports Medicine
影响因子:11.7
doi:10.1016/j.xcrm.2023.101150
Jacob Gadwa ，Maria Amann ，Thomas E Bickett ，Michael W Knitz ，Laurel B Darragh ，Miles Piper ，Benjamin Van Court ，Sanjana Bukkapatnam ，Tiffany T Pham ，Xiao-Jing Wang ，Anthony J Saviola ，Laura Codarri Deak ，Pablo Umaña ，Christian Klein ，Angelo D'Alessandro ，Sana D Karam
免疫/内分泌
T细胞
肿瘤免疫
细胞生物学
IL2
肿瘤
CD8
发表日期：2023
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Vasculitis, CA19-9, and Perineural Invasion Differentially Predict Response and Surgical Outcome in Pancreatic Ductal Adenocarcinoma

血管炎、CA19-9 和神经周围浸润对胰腺导管腺癌的治疗反应和手术结果具有不同的预测价值

期刊:International Journal of Radiation Oncology Biology Physics
影响因子:6.5
doi:10.1016/j.ijrobp.2022.12.039
Piper, Miles; Ross, Richard Blake; Hu, Junxiao; Watanabe, Shuichi; Knitz, Michael; Mehrotra, Sanjana; Shulick, Richard; Chiaro, Marco Del; Karam, Sana D
肿瘤
肿瘤免疫
发表日期：2023
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