The development of N-α-(2-carboxyl)benzoyl-N(5)-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-F-amidine) and N-α-(2-carboxyl)benzoyl-N(5)-(2-chloro-1-iminoethyl)-l-ornithine amide (o-Cl-amidine) as second generation protein arginine deiminase (PAD) inhibitors
N-α-(2-羧基)苯甲酰-N(5)-(2-氟-1-亚氨基乙基)-1-鸟氨酸酰胺 (oF-脒) 和 N-α-(2-羧基)苯甲酰-N(5)-(2-氯-1-亚氨基乙基)-1-鸟氨酸酰胺 (o-Cl-脒) 作为第二代蛋白质精氨酸脱亚氨酶 (PAD) 抑制剂的开发
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm2008985
Corey P Causey, Justin E Jones, Jessica L Slack, Daisuke Kamei, Larry E Jones, Venkataraman Subramanian, Bryan Knuckley, Pedram Ebrahimi, Alexander A Chumanevich, Yuan Luo, Hiroshi Hashimoto, Mamoru Sato, Lorne J Hofseth, Paul R Thompson
