日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lysosomal protease-mediated APP degradation is pH-dependent, mutation-sensitive, and facilitates tau proteolysis.

溶酶体蛋白酶介导的 APP 降解是 pH 依赖性的、对突变敏感的,并且促进 tau 蛋白水解。

Ackley Caroline, Liau Zoe, Arya Shruti, Antee Tara, Cheang Emily, Knudsen Giselle M, Lane-Donovan Courtney, Sampognaro Paul J, Kao Aimee W

Lysosomal Protease-Mediated APP Degradation is pH-Dependent, Mutation-Sensitive, and Facilitates Tau Proteolysis.

溶酶体蛋白酶介导的 APP 降解依赖于 pH 值,对突变敏感,并促进 Tau 蛋白水解

Ackley Caroline, Liau Zoe, Arya Shruti, Antee Tara, Knudsen Giselle M, Lane-Donovan Courtney, Sampognaro Paul J, Kao Aimee W

Correction: Mutations in α-synuclein, TDP-43 and tau prolong protein half-life through diminished degradation by lysosomal proteases

更正:α-突触核蛋白、TDP-43和tau蛋白的突变会通过减少溶酶体蛋白酶的降解来延长蛋白质的半衰期。

Sampognaro, Paul J; Arya, Shruti; Knudsen, Giselle M; Gunderson, Emma L; Sandoval-Perez, Angelica; Hodul, Molly; Bowles, Kathryn; Craik, Charles S; Jacobson, Matthew P; Kao, Aimee W

Exploratory proteomic analysis implicates the alternative complement cascade in primary CNS vasculitis.

探索性蛋白质组学分析表明,替代补体级联反应与原发性中枢神经系统血管炎有关

Mandel-Brehm Caleigh, Retallack Hanna, Knudsen Giselle M, Yamana Alex, Hajj-Ali Rula A, Calabrese Leonard H, Tihan Tarik, Sample Hannah A, Zorn Kelsey C, Gorman Mark P, Madan Cohen Jennifer, Sreih Antoine G, Marcus Jacqueline F, Josephson S Andrew, Douglas Vanja C, Gelfand Jeffrey M, Wilson Michael R, DeRisi Joseph L

Global substrate specificity profiling of post-translational modifying enzymes

翻译后修饰酶的全局底物特异性分析

Ivry, Sam L; Meyer, Nicole O; Winter, Michael B; Bohn, Markus F; Knudsen, Giselle M; O'Donoghue, Anthony J; Craik, Charles S

Comparative genomic, transcriptomic, and proteomic reannotation of human herpesvirus 6

人类疱疹病毒6的比较基因组学、转录组学和蛋白质组学重新注释

Greninger, Alexander L; Knudsen, Giselle M; Roychoudhury, Pavitra; Hanson, Derek J; Sedlak, Ruth Hall; Xie, Hong; Guan, Jon; Nguyen, Thuy; Peddu, Vikas; Boeckh, Michael; Huang, Meei-Li; Cook, Linda; Depledge, Daniel P; Zerr, Danielle M; Koelle, David M; Gantt, Soren; Yoshikawa, Tetsushi; Caserta, Mary; Hill, Joshua A; Jerome, Keith R

Affinity purification-mass spectrometry and network analysis to understand protein-protein interactions

利用亲和纯化-质谱和网络分析来理解蛋白质-蛋白质相互作用

Morris, John H; Knudsen, Giselle M; Verschueren, Erik; Johnson, Jeffrey R; Cimermancic, Peter; Greninger, Alexander L; Pico, Alexander R

Substrate specificity of MarP, a periplasmic protease required for resistance to acid and oxidative stress in Mycobacterium tuberculosis

结核分枝杆菌周质蛋白酶MarP的底物特异性,MarP是结核分枝杆菌抵抗酸和氧化应激所必需的。

Small, Jennifer L; O'Donoghue, Anthony J; Boritsch, Eva C; Tsodikov, Oleg V; Knudsen, Giselle M; Vandal, Omar; Craik, Charles S; Ehrt, Sabine

Examination of the mode of action of the almiramide family of natural products against the kinetoplastid parasite Trypanosoma brucei

研究天然产物阿米拉米德家族对动质体寄生虫布氏锥虫的作用机制

Sanchez, Laura M; Knudsen, Giselle M; Helbig, Claudia; De Muylder, Geraldine; Mascuch, Samantha M; Mackey, Zachary B; Gerwick, Lena; Clayton, Christine; McKerrow, James H; Linington, Roger G

A minimal anaphase promoting complex/cyclosome (APC/C) in Trypanosoma brucei.

布氏锥虫中的最小后期促进复合物/细胞周期体(APC/C)

Bessat Mohamed, Knudsen Giselle, Burlingame Alma L, Wang Ching C