日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Expression of ubiquitin carboxyl-terminal hydrolase isozyme L1 and chromogranin A regulated via histone-modification through Rho/ERK/NFκB signaling in oxaliplatin-resistant colorectal cancer cells

在奥沙利铂耐药性结直肠癌细胞中，泛素羧基末端水解酶同工酶L1和嗜铬粒蛋白A的表达受Rho/ERK/NFκB信号通路介导的组蛋白修饰调控

期刊:International Journal of Medical Sciences
影响因子:3.2
doi:10.7150/ijms.126460
Lee, Ko-Chao; Cheng, Kung-Chuan; Huang, Cheng-Yi; Hsieh, Meng-Chiao; Tung, Shui-Yi; Hsieh, Yung-Yu; Lee, Kam-Fai; Teng, Chih-Chuan; Kuo, Hsing-Chun
肿瘤
肠癌
表观遗传
肿瘤免疫
信号转导
组蛋白修饰
MAPK/ERK
细胞生物学
发表日期：2026
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Survival impact of radiotherapy for patients with de novo metastatic rectal cancer

放射治疗对新发转移性直肠癌患者生存率的影响

期刊:Annals of Coloproctology
影响因子:2.1
doi:10.3393/ac.2025.00605.0086
Su, Harvey Yu-Li; Lin, Yun-Hsuan; Lee, Ko-Chao; Lin, Yueh-Ming; Huang, Chun-Chieh; Huang, Eng-Yen; Chiu, Tai-Jan; Huang, Shih-Yu; Wu, Chia-Che; Lin, Chang-Ting; Kuo, Ming-Chun; Tsai, Kai-Lung
肿瘤
肠癌
肿瘤免疫
发表日期：2026
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A Novel Erinacine S Derivative from Hericium erinaceus Overcomes Chemoresistance in Colorectal Cancer Cells by Enhancing TRAIL/TNFR1/DR5 Expression through Histone Acetylation

一种来自猴头菇的新型Erinacine S衍生物通过组蛋白乙酰化增强TRAIL/TNFR1/DR5的表达，从而克服结直肠癌细胞的化疗耐药性。

期刊:International Journal of Medical Sciences
影响因子:3.2
doi:10.7150/ijms.119894
Tung, Shui-Yi; Lee, Kam-Fai; Hsieh, Yung-Yu; Cheng, Kung-Chuan; Lee, Ko-Chao; Lee, Li-Ya; Chen, Wan-Ping; Chen, Chin-Chu; Teng, Chih-Chuan; Hsieh, Meng-Chiao; Huang, Cheng-Yi; Kuo, Hsing-Chun
肿瘤
肠癌
表观遗传
肿瘤免疫
TRAIL
乙酰化
细胞生物学
发表日期：2025
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Molecular mechanisms and biomarkers of total parenteral nutrition-induced hepatotoxicity revealed by iTRAQ proteomics analysis

iTRAQ蛋白质组学分析揭示全肠外营养诱导肝毒性的分子机制和生物标志物

期刊:International Journal of Medical Sciences
影响因子:3.2
doi:10.7150/ijms.122025
Hsieh, Yung-Yu; Tsai, Jai-Jen; Tung, Shui-Yi; Lee, Ko-Chao; Cheng, Kung-Chuan; Lee, Kam-Fai; Hsieh, Meng-Chiao; Huang, Cheng-Yi; Teng, Chih-Chuan; Shen, Chien-Heng; Kuo, Hsing-Chun
毒理研究
发表日期：2025
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Impact of iron-deficiency anemia on short-term outcomes after resection of colorectal cancer liver metastasis: a US National (Nationwide) Inpatient Sample (NIS) analysis

缺铁性贫血对结直肠癌肝转移切除术后短期预后的影响：一项基于美国全国住院患者样本（NIS）的分析

期刊:Annals of Coloproctology
影响因子:2.1
doi:10.3393/ac.2024.00591.0084
Lee, Ko-Chao; Su, Yu-Li; Wu, Kuen-Lin; Cheng, Kung-Chuan; Song, Ling-Chiao; Tang, Chien-En; Chen, Hong-Hwa; Chung, Kuan-Chih
肿瘤
肠癌
肿瘤免疫
代谢
贫血
发表日期：2025
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Muscle loss phenotype predicts poor postoperative outcomes of colorectal cancer in US inpatients: a population-based analysis

肌肉萎缩表型可预测美国住院结直肠癌患者术后不良预后：一项基于人群的分析

期刊:Annals of Coloproctology
影响因子:2.1
doi:10.3393/ac.2025.00129.0018
Lee, Ko-Chao; Juang, Sin-Ei; Wu, Kuen-Lin; Cheng, Kung-Chuan; Song, Ling-Chiao; Tang, Chien-En; Chen, Hong-Hwa; Chung, Kuan-Chih
肿瘤
肠癌
肿瘤免疫
发表日期：2025
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The Cerebral Protective Effect of Novel Erinacines from Hericium erinaceus Mycelium on In Vivo Mild Traumatic Brain Injury Animal Model and Primary Mixed Glial Cells via Nrf2-Dependent Pathways

猴头菇菌丝体中新型猴头菇素通过Nrf2依赖性通路对体内轻度创伤性脑损伤动物模型和原代混合胶质细胞的脑保护作用

期刊:Antioxidants
影响因子:6.6
doi:10.3390/antiox13030371
Lee, Kam-Fai; Hsieh, Yung-Yu; Tung, Shui-Yi; Teng, Chih-Chuan; Cheng, Kung-Chuan; Hsieh, Meng-Chiao; Huang, Cheng-Yi; Lee, Ko-Chao; Lee, Li-Ya; Chen, Wan-Ping; Chen, Chin-Chu; Kuo, Hsing-Chun
胶质细胞
信号转导
细胞生物学
神经科学
发表日期：2024
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Amphiregulin Upregulation in Visfatin-Stimulated Colorectal Cancer Cells Reduces Sensitivity to 5-Fluororacil Cytotoxicity.

在内脏脂肪素刺激的结直肠癌细胞中，双调蛋白的上调降低了对 5-氟尿嘧啶细胞毒性的敏感性

期刊:Biology-Basel
影响因子:3.5
doi:10.3390/biology13100821
Huang Wen-Shih, Wu Kuen-Lin, Chen Cheng-Nan, Chang Shun-Fu, Lee Ding-Yu, Lee Ko-Chao
细胞生物学
肠癌
发表日期：2024
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Prognostic value of neutrophil-to-lymphocyte ratios pre- and post-surgery in stage III CRC: a study of 2,742 patients

中性粒细胞与淋巴细胞比值在III期结直肠癌术前术后的预后价值：一项纳入2742例患者的研究

期刊:International Journal of Colorectal Disease
影响因子:2.3
doi:10.1007/s00384-024-04789-3
Lee, Yun; Cheng, Kung-Chuan; Lin, Yueh-Ming; Lu, Chien-Chang; Lee, Ko-Chao
肿瘤
肠癌
中性粒细胞
肿瘤免疫
粒细胞
细胞生物学
发表日期：2024
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Antrodin C Isolated from Antrodia Cinnamomea Induced Apoptosis through ROS/AKT/ERK/P38 Signaling Pathway and Epigenetic Histone Acetylation of TNFα in Colorectal Cancer Cells

从牛樟芝中分离得到的牛樟芝素C通过ROS/AKT/ERK/P38信号通路和TNFα的表观遗传组蛋白乙酰化诱导结直肠癌细胞凋亡

期刊:Antioxidants
影响因子:6.6
doi:10.3390/antiox12030764
Hsieh, Yung-Yu; Lee, Ko-Chao; Cheng, Kung-Chuan; Lee, Kam-Fai; Yang, Ya-Ling; Chu, Hsin-Tung; Lin, Ting-Wei; Chen, Chin-Chu; Hsieh, Meng-Chiao; Huang, Cheng-Yi; Kuo, Hsing-Chun; Teng, Chih-Chuan
肿瘤
肠癌
表观遗传
肿瘤免疫
凋亡
Apoptosis
信号转导
MAPK/ERK
乙酰化
细胞生物学
AKT
TNFα
发表日期：2023
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