Loss of Pol III repressor Maf1 in neurons promotes longevity by preventing the age-related decline in 5S rRNA and translation.
神经元中 Pol III 抑制因子 Maf1 的缺失可防止 5S rRNA 和翻译随年龄增长而下降,从而促进寿命延长
期刊:PLoS Biology
影响因子:7.2
doi:10.1371/journal.pbio.3003250
Xu Bowen, Hull Alexander, Hill Olivia N M, Kobal Naja, Ureña Enric, Partridge Linda, Alic Nazif