日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Competition between a transmembrane helix on Scap and a membrane cholesterol regulates Scap-Insig interaction and SREBP activation

Scap 上的跨膜螺旋与膜胆固醇之间的竞争调节 Scap-Insig 相互作用和 SREBP 激活。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2525043123
Williams, Blake C; Kober, Daniel L; Bai, Xiao-Chen; Rosenbaum, Daniel M; Radhakrishnan, Arun
EBP
代谢
发表日期：2026
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Structural basis for substrate selectivity by site-one protease revealed by studies with a small-molecule inhibitor

利用小分子抑制剂的研究揭示了位点一蛋白酶底物选择性的结构基础

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2426931122
Bullington, Ashley V; Micallo, Ilaria; Bajaj, Bilkish; Kumar, Pankaj; Schlamowitz, Netanya; Silva, Aurora; Hendrix, Sebastian; Zelcer, Noam; Kober, Daniel L
发表日期：2025
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NPC1 trafficking via VPS41-dependent LAMP carriers regulates endosomal cholesterol homeostasis

NPC1通过VPS41依赖的LAMP载体进行运输，从而调节内体胆固醇稳态。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2521979122
Ndoj, Klevis; Tantucci, Matteo; Sanza, Paolo; Zubak, Kristian; Marodin, Giorgia; Kingma, Jenina; Snijder, Felix; Veenendaal, Tineke; Kober, Daniel L; Zelcer, Noam; Klumperman, Judith
NPC1
VPS41
代谢
发表日期：2025
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SPRINGing off the lock: the role of SPRING in S1P activity and SREBP-regulated lipid metabolism

挣脱束缚：SPRING 在 S1P 活性和 SREBP 调控的脂质代谢中的作用

期刊:
影响因子:
doi:10.1097/MOL.0000000000001003
Micallo, Ilaria; Bullington, Ashley V; Kober, Daniel L; Zelcer, Noam
信号转导
EBP
代谢
发表日期：2025
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Choreography of human mitochondrial leaderless mRNA translation initiation.

人类线粒体无前导序列mRNA翻译起始的编排

期刊:
影响因子:
doi:10.1101/2025.07.10.662049
Shen Shuangjie, Xu Yinghua, Kober Daniel L, Wang Jinfan
其它
Human
线粒体
发表日期：2025
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Structures of the multi-domain oxygen sensor DosP: remote control of a c-di-GMP phosphodiesterase by a regulatory PAS domain

多结构域氧传感器DosP的结构：通过调控性PAS结构域远程控制c-di-GMP磷酸二酯酶

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-024-53942-7
Wu, Wenbi; Kumar, Pankaj; Brautigam, Chad A; Tso, Shih-Chia; Baniasadi, Hamid R; Kober, Daniel L; Gilles-Gonzalez, Marie-Alda
信号转导
发表日期：2024
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SPRING is a Dedicated Licensing Factor for SREBP-Specific Activation by S1P.

SPRING 是 S1P 为 SREBP 特定激活而专门提供的许可因子

期刊:Molecular and Cellular Biology
影响因子:2.7
doi:10.1080/10985549.2024.2348711
Hendrix Sebastian, Tan Josephine M E, Ndoj Klevis, Kingma Jenina, Valiloo Masoud, Zijlstra Lobke F, Ottenhoff Roelof, Seidah Nabil G, Loregger Anke, Kober Daniel L, Zelcer Noam
其它
发表日期：2024
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Identification of a degradation signal at the carboxy terminus of SREBP2: A new role for this domain in cholesterol homeostasis

SREBP2羧基末端降解信号的鉴定：该结构域在胆固醇稳态中的新作用

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2018578117
Kober, Daniel L; Xu, Shimeng; Li, Shili; Bajaj, Bilkish; Liang, Guosheng; Rosenbaum, Daniel M; Radhakrishnan, Arun
信号转导
EBP
代谢
发表日期：2020
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YbtT is a low-specificity type II thioesterase that maintains production of the metallophore yersiniabactin in pathogenic enterobacteria

YbtT 是一种低特异性的 II 型硫酯酶，它维持致病性肠杆菌中金属载体耶尔森氏菌素的产生。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.RA118.005752
Ohlemacher, Shannon I; Xu, Yiquan; Kober, Daniel L; Malik, Mahnoor; Nix, Jay C; Brett, Tom J; Henderson, Jeffrey P
发表日期：2018
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