Koczan Dirk相关文献与解析，生知库 | 链接生命科学的每一步

CDK inhibitors promote neuroblastoma cell differentiation and increase sensitivity to retinoic acid-a promising combination strategy for therapeutic intervention.

CDK 抑制剂可促进神经母细胞瘤细胞分化，并提高对维甲酸的敏感性——这是一种有前景的联合治疗策略

Shokraie Fatemeh, Lechermeier Larissa, Bordihn Pia, Kaps Philipp, MÃ¶ller Steffen, Schulz Anna Sophie, Schneider BjÃ¶rn, Koczan Dirk, Roshan Samira Khanipour, Lode Holger N, Classen Carl-Friedrich, Hahn Olga, Troschke-Meurer Sascha, Maletzki Claudia

神经科学

发表日期：2025

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Tumor treating fields alter local coagulation dynamics in glioblastoma patients

肿瘤电场治疗会改变胶质母细胞瘤患者的局部凝血动力学

期刊:Neurotherapeutics

影响因子:6.9

doi:10.1016/j.neurot.2025.e00715

Maletzki, Claudia; Freitag, Thomas; Hempelmann, Adrian; Wolff, Annabell; Freiman, Thomas M; Won, Sae-Yeon; Koczan, Dirk; Sender, Sina; Valdes, Pablo A; Bernstock, Joshua D; Gessler, Florian; Dubinski, Daniel

A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impairments

一种独特的肥胖多基因小鼠模型表现出独特的免疫学特征，可能对全身炎症、糖尿病和行为障碍提供保护作用。

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2025.1601809

Gimsa, Ulrike; Koczan, Dirk; Kanitz, Ellen; Tuchscherer, Armin; Rebl, Alexander

Apheresis for the treatment of relapses in MS and NMOSD: reduced antibody reactivities, gene expression changes and potential clinical response indicators

血浆置换疗法治疗多发性硬化症和视神经脊髓炎谱系疾病复发：抗体反应性降低、基因表达改变及潜在临床反应指标

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2025.1531447

Hecker, Michael; Fitzner, Brit; Ludwig-Portugall, Isis; Bohne, Friederike; Heyland, Edmar; Klehmet, Juliane; Grothe, Matthias; Schwab, Matthias; Winkelmann, Alexander; Meister, Stefanie; Dudesek, Ales; Wurm, Hannah; Ayzenberg, Ilya; Kleiter, Ingo; Trebst, Corinna; Hümmert, Martin W; Neumann, Bernhard; Eulitz, Klaus; Koczan, Dirk; Zettl, Uwe K

Comparative analysis of PI3K-AKT and MEK-ERK1/2 signaling-driven molecular changes in granulosa cells.

PI3K-AKT 和 MEK-ERK1/2 信号通路驱动的颗粒细胞分子变化的比较分析

期刊:Reproduction

影响因子:3.7

doi:10.1530/REP-24-0317

Baddela Vijay Simha, Michaelis Marten, Tao Xuelian, Koczan Dirk, Brenmoehl Julia, Vanselow Jens

Transcriptome alterations in peripheral blood B cells of patients with multiple sclerosis receiving immune reconstitution therapy

接受免疫重建治疗的多发性硬化症患者外周血B细胞转录组改变

期刊:Journal of Neuroinflammation

影响因子:10.1

doi:10.1186/s12974-023-02859-x

Hecker, Michael; Fitzner, Brit; Boxberger, Nina; Putscher, Elena; Engelmann, Robby; Bergmann, Wendy; Müller, Michael; Ludwig-Portugall, Isis; Schwartz, Margit; Meister, Stefanie; Dudesek, Ales; Winkelmann, Alexander; Koczan, Dirk; Zettl, Uwe Klaus

Red blood cells in proliferative kidney disease-rainbow trout (Oncorhynchus mykiss) infected by Tetracapsuloides bryosalmonae harbor IgM(+) red blood cells

增生性肾病——感染了四囊藻（Tetracapsuloides bryosalmonae）的虹鳟（Oncorhynchus mykiss）的红细胞中含有IgM(+)红细胞

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2023.1041325

Chan, Justin T H; Picard-Sánchez, Amparo; Majstorović, Jovana; Rebl, Alexander; Koczan, Dirk; Dyčka, Filip; Holzer, Astrid S; Korytář, Tomáš

Exploring Thiazolopyridine AV25R: Unraveling of Biological Activities, Selective Anti-Cancer Properties and In Silico Target and Binding Prediction in Hematological Neoplasms

探索噻唑并吡啶类化合物AV25R：揭示其在血液肿瘤中的生物活性、选择性抗癌特性以及计算机靶点和结合预测

期刊:Molecules

影响因子:4.6

doi:10.3390/molecules28248120

Ladwig, Annika; Gupta, Shailendra; Ehlers, Peter; Sekora, Anett; Alammar, Moosheer; Koczan, Dirk; Wolkenhauer, Olaf; Junghanss, Christian; Langer, Peter; Murua Escobar, Hugo

Early milk-feeding regimes in calves exert long-term effects on the development of ovarian granulosa cells

犊牛早期哺乳方式对卵巢颗粒细胞的发育具有长期影响。

期刊:BMC Genomics

影响因子:3.7

doi:10.1186/s12864-023-09589-7

Röttgen, Volker; Tümmler, Lisa-Maria; Koczan, Dirk; Rebl, Alexander; Kuhla, Björn; Vanselow, Jens; Baufeld, Anja

PDK4 is critical for metabolic regulation and progesterone production in bovine granulosa cells†

PDK4 对牛颗粒细胞的代谢调控和孕酮生成至关重要†

CDK inhibitors promote neuroblastoma cell differentiation and increase sensitivity to retinoic acid-a promising combination strategy for therapeutic intervention.

CDK 抑制剂可促进神经母细胞瘤细胞分化，并提高对维甲酸的敏感性——这是一种有前景的联合治疗策略

Tumor treating fields alter local coagulation dynamics in glioblastoma patients

肿瘤电场治疗会改变胶质母细胞瘤患者的局部凝血动力学

A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impairments

一种独特的肥胖多基因小鼠模型表现出独特的免疫学特征，可能对全身炎症、糖尿病和行为障碍提供保护作用。

Apheresis for the treatment of relapses in MS and NMOSD: reduced antibody reactivities, gene expression changes and potential clinical response indicators

血浆置换疗法治疗多发性硬化症和视神经脊髓炎谱系疾病复发：抗体反应性降低、基因表达改变及潜在临床反应指标

Comparative analysis of PI3K-AKT and MEK-ERK1/2 signaling-driven molecular changes in granulosa cells.

PI3K-AKT 和 MEK-ERK1/2 信号通路驱动的颗粒细胞分子变化的比较分析

Transcriptome alterations in peripheral blood B cells of patients with multiple sclerosis receiving immune reconstitution therapy

接受免疫重建治疗的多发性硬化症患者外周血B细胞转录组改变

Red blood cells in proliferative kidney disease-rainbow trout (Oncorhynchus mykiss) infected by Tetracapsuloides bryosalmonae harbor IgM(+) red blood cells

增生性肾病——感染了四囊藻（Tetracapsuloides bryosalmonae）的虹鳟（Oncorhynchus mykiss）的红细胞中含有IgM(+)红细胞

Exploring Thiazolopyridine AV25R: Unraveling of Biological Activities, Selective Anti-Cancer Properties and In Silico Target and Binding Prediction in Hematological Neoplasms

探索噻唑并吡啶类化合物AV25R：揭示其在血液肿瘤中的生物活性、选择性抗癌特性以及计算机靶点和结合预测

Early milk-feeding regimes in calves exert long-term effects on the development of ovarian granulosa cells

犊牛早期哺乳方式对卵巢颗粒细胞的发育具有长期影响。