日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Proximity-driven acceleration of challenging solid-phase peptide couplings

邻近效应驱动的固相肽偶联反应加速

Parker, Joshua; Farrell, Brooke A; Kohuth, Karlee A; Parker, Landon; Abboud, Skander A; Kodadek, Thomas

Exploiting Avidity Effects for the Discovery of Low Affinity Protein-Binding Fragments

利用亲和力效应发现低亲和力蛋白结合片段

Jayalath, Isuru M; Beckwith, Donella; Yoon, Jihyeon; Liu, Xingui; Kodadek, Thomas

Macrocyclic Peptides Containing an Imidazopyridinium (IP(+)) Unit Display Enhanced Passive Cell Permeability

含有咪唑并吡啶鎓 (IP(+)) 单元的大环肽表现出增强的被动细胞渗透性

Li, Bo; Parker, Joshua; Briggs, Skyler; Dong, Jiajun; Burke, James M; Kodadek, Thomas

Synthesis of Membrane-Permeable Macrocyclic Peptides via Imidazopyridinium Grafting

通过咪唑并吡啶鎓接枝合成膜渗透性大环肽

Li, Bo; Parker, Joshua; Tong, Joel; Kodadek, Thomas

Identification and characterization of a nonbiological small-molecular mimic of a Zika virus conformational neutralizing epitope

寨卡病毒构象中和表位的非生物小分子模拟物的鉴定和表征

Castanha, Priscila M S; McEnaney, Patrick J; Park, Yongseok; Bouwer, Anthea; Chaves, Elton J F; Lins, Roberto D; Paciaroni, Nicholas G; Dickson, Paige; Carlson, Graham; Cordeiro, Marli T; Magalhaes, Tereza; Craigo, Jodi; Marques, Ernesto T A; Kodadek, Thomas; Burke, Donald S

Solid-Phase Synthesis of Diverse Macrocycles by Regiospecific 2-Pyridone Formation: Scope and Applications

通过区域选择性2-吡啶酮形成固相合成多种大环化合物:范围和应用

Abboud, Skander A; Kodadek, Thomas

Recruitment to the Proteasome Is Necessary but Not Sufficient for Chemically Induced, Ubiquitin-Independent Degradation of Native Proteins

蛋白酶体的募集是化学诱导的、不依赖于泛素的天然蛋白质降解的必要条件,但并非充分条件。

Balzarini, Madeline; Tong, Joel; Gui, Weijun; Jayalath, Isuru M; Schell, Bin-Bin; Kodadek, Thomas

2-Pyridone Formation: An Efficient Method for the Solid-Phase Synthesis of Homodimers

2-吡啶酮的形成:一种高效的均二聚体固相合成方法

Abboud, Skander A; Kodadek, Thomas

Facile Synthesis of Homodimeric Protein Ligands

同源二聚体蛋白配体的简易合成

Gui, Weijun; Kodadek, Thomas

High-Throughput Quality Control Assay for the Solid-Phase Synthesis of DNA-Encoded Libraries of Macrocycles*

用于固相合成DNA编码大环化合物库的高通量质量控制检测方法*

Roy, Animesh; Koesema, Eric; Kodadek, Thomas