Vectorization in an oncolytic vaccinia virus of an antibody, a Fab and a scFv against programmed cell death -1 (PD-1) allows their intratumoral delivery and an improved tumor-growth inhibition
溶瘤痘苗病毒中针对程序性细胞死亡-1 (PD-1) 的抗体、Fab 和 scFv 的载体化可实现肿瘤内递送,从而改善肿瘤生长抑制
期刊:Oncoimmunology
影响因子:
doi:10.1080/2162402X.2016.1220467
Patricia Kleinpeter, Laetitia Fend, Christine Thioudellet, Michel Geist, Nathalie Sfrontato, Véronique Koerper, Catherine Fahrner, Doris Schmitt, Murielle Gantzer, Christelle Remy-Ziller, Renée Brandely, Dominique Villeval, Karola Rittner, Nathalie Silvestre, Philippe Erbs, Laurence Zitvogel, Eric Q