日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Unnatural Cytosine Analogs Potentiate a Customizable, Enzymatic Method for Integrated Epigenetic and Four-Base Genetic Sequencing

非天然胞嘧啶类似物增强了一种可定制的酶促方法,用于整合表观遗传学和四碱基基因测序

Loo, Christian E; Parker, Jared B; Barka, Aleksia; Zhu, Ruiyao; Schnell, Matthew R; Cuomo, Rosella G; Zhu, Heqiao; Liu, Laura; Chen, Ashley; Gill, Jasleen; Zhou, Wanding; Kohli, Rahul M

A ternary-code DNA methylome atlas of mouse tissues

小鼠组织三元编码DNA甲基化组图谱

Lee, Sol Moe; Goldberg, David C; Cloud, Cameron; Parker, Jared B; Krapp, Christopher; Loo, Christian E; Kim, Elliot; Zhao, Ivan; Jin, Chengcheng; Porecha, Rishi; Bartolomei, Marisa S; Kohli, Rahul M; Zhou, Wanding

Neomorphic leukemia-derived mutations in the TET2 enzyme induce genome instability via a substrate shift from 5-methylcytosine to thymine

白血病衍生的TET2酶新突变通过底物由5-甲基胞嘧啶转变为胸腺嘧啶,诱导基因组不稳定。

Jin, Guang-Bo; Rong, Shao-Qin; Yin, Dong-Rui; Deng, Zhou-Hao; Ding, Xiao; Sheng, Meng-Yao; Gao, Hai; Kohli, Rahul M; Xu, Guo-Liang; Zhou, Dan

Scalable screening of ternary-code DNA methylation dynamics associated with human traits

可扩展筛选与人类性状相关的三元编码DNA甲基化动态

Goldberg, David C; Cloud, Cameron; Lee, Sol Moe; Barnes, Bret; Gruber, Steven; Kim, Elliot; Pottekat, Anita; Westphal, Maximillian S; McAuliffe, Luana; Majounie, Elisa; Kalayil Manian, Manesh; Zhu, Qingdi; Tran, Christine; Hansen, Mark; Stojakovic, Jelena; Parker, Jared B; Kohli, Rahul M; Porecha, Rishi; Renke, Nicole; Zhou, Wanding

The bacterial stress response polymerase DinB tolerates sugar modifications and preferentially incorporates arabinosyl nucleotides

细菌应激反应聚合酶DinB能够耐受糖修饰,并优先掺入阿拉伯糖基核苷酸。

Hurley, Christina M; Kubiak, Jeffrey M; Cory, Michael B; Parker, Jared B; Loo, Christian E; Wang, Laura C; Kohli, Rahul M

IMG-01. Higher Cerebral Metabolic Rate of Oxygen derived from Dynamic Susceptibility Contrast MRI is an Independent Predictor of Poor Survival in IDH-Wildtype Glioblastoma

IMG-01. 动态磁敏感对比磁共振成像(DSC-MRI)显示的较高脑氧代谢率是IDH野生型胶质母细胞瘤患者预后不良的独立预测因子

Zhu, Ruiyao; Loo, Christian E; Hurley, Christina M; Parker, Jared B; Kohli, Rahul M; Park, Yae Won; Ahn, Sung Soo; Chang, Jong Hee; Kim, Se Hoon

The LexA-RecA* structure reveals a cryptic lock-and-key mechanism for SOS activation

LexA-RecA*结构揭示了一种用于SOS激活的隐秘锁钥机制。

Cory, Michael B; Li, Allen; Hurley, Christina M; Carman, Peter J; Pumroy, Ruth A; Hostetler, Zachary M; Perez, Ryann M; Venkatesh, Yarra; Li, Xinning; Gupta, Kushol; Petersson, E James; Kohli, Rahul M

Iterative oxidation by TET1 is required for reprogramming of imprinting control regions and patterning of mouse sperm hypomethylated regions.

TET1 的迭代氧化作用是重编程印记控制区和小鼠精子低甲基化区模式所必需的

Prasasya Rexxi D, Caldwell Blake A, Liu Zhengfeng, Wu Songze, Leu N Adrian, Fowler Johanna M, Cincotta Steven A, Laird Diana J, Kohli Rahul M, Bartolomei Marisa S

Critical assessment of nanopore sequencing for the detection of multiple forms of DNA modifications

对纳米孔测序技术在检测多种DNA修饰方面的批判性评估

Kong, Yimeng; Zhang, Yanchun; Mead, Edward A; Chen, Hao; Loo, Christian E; Fan, Yu; Ni, Mi; Zhang, Xue-Song; Kohli, Rahul M; Fang, Gang

FRETing about the details: Case studies in the use of a genetically encoded fluorescent amino acid for distance-dependent energy transfer

细节上的FRET:利用基因编码的荧光氨基酸进行距离依赖性能量转移的案例研究

Cory, Michael B; Jones, Chloe M; Shaffer, Kyle D; Venkatesh, Yarra; Giannakoulias, Sam; Perez, Ryann M; Lougee, Marshall G; Hummingbird, Eshe; Pagar, Vinayak V; Hurley, Christina M; Li, Allen; Mach, Robert H; Kohli, Rahul M; Petersson, E James